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1C12
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BU of 1c12 by Molmil
INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE
Descriptor: PROTEIN (ANTIBODY FRAGMENT FAB), TRAZEOLIDE
Authors:Langedijk, A.C, Spinelli, S, Anguille, C, Hermans, P, Nederlof, J, Butenandt, J, Honegger, A, Cambillau, C, Pluckthun, A.
Deposit date:1999-07-20
Release date:1999-08-14
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insight into odorant perception: the crystal structure and binding characteristics of antibody fragments directed against the musk odorant traseolide.
J.Mol.Biol., 292, 1999
1C5E
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BU of 1c5e by Molmil
BACTERIOPHAGE LAMBDA HEAD PROTEIN D
Descriptor: GLYCEROL, HEAD DECORATION PROTEIN
Authors:Yang, F, Forrer, P, Dauter, Z, Pluckthun, A, Wlodawer, A.
Deposit date:1999-11-18
Release date:2000-03-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Novel fold and capsid-binding properties of the lambda-phage display platform protein gpD.
Nat.Struct.Biol., 7, 2000
6YJ1
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BU of 6yj1 by Molmil
The M23 peptidase domain of the Staphylococcal phage 2638A endolysin
Descriptor: ORF007, ZINC ION
Authors:Dunne, M, Ernst, P, Sobieraj, A, Pluckthun, A, Loessner, M.J.
Deposit date:2020-04-02
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(CASP target) Crystal structure of the M23 peptidase domain of Staphylococcal phage 2638A endolysin
To Be Published
1G3P
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BU of 1g3p by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAINS OF BACTERIOPHAGE MINOR COAT PROTEIN G3P
Descriptor: MINOR COAT PROTEIN, SULFATE ION
Authors:Lubkowski, J, Hennecke, F, Pluckthun, A, Wlodawer, A.
Deposit date:1997-12-22
Release date:1998-01-28
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:The structural basis of phage display elucidated by the crystal structure of the N-terminal domains of g3p.
Nat.Struct.Biol., 5, 1998
4V3Q
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BU of 4v3q by Molmil
Designed armadillo repeat protein with 4 internal repeats, 2nd generation C-cap and 3rd generation N-cap.
Descriptor: CALCIUM ION, GLYCEROL, YIII_M4_AII
Authors:Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P.
Deposit date:2014-10-20
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects.
Acta Crystallogr D Struct Biol, 72, 2016
4V3O
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BU of 4v3o by Molmil
Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap.
Descriptor: ACETATE ION, CALCIUM ION, YIII_M5_AII
Authors:Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P.
Deposit date:2014-10-20
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects
Acta Crystallogr.,Sect.D, 72, 2016
4V3R
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BU of 4v3r by Molmil
Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap.
Descriptor: MAGNESIUM ION, YIII_M5_AII
Authors:Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P.
Deposit date:2014-10-20
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects
Acta Crystallogr.,Sect.D, 72, 2016
3HG0
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BU of 3hg0 by Molmil
Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1
Descriptor: Baseplate protein, Designed Ankyrin Repeat Protein (DARPin) 20
Authors:Veesler, D, Dreier, B, Blangy, S, Lichiere, J, Tremblay, D, Moineau, S, Spinelli, S, Tegoni, M, Pluckthun, A, Campanacci, V, Cambillau, C.
Deposit date:2009-05-13
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode.
J.Biol.Chem., 284, 2009
1VD0
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BU of 1vd0 by Molmil
Capsid stabilizing protein GPD, NMR, 20 Structures
Descriptor: Head decoration protein
Authors:Iwai, H, Forrer, P, Pluckthun, A, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-17
Release date:2005-03-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR solution structure of the monomeric form of the bacteriophage lambda capsid stabilizing protein gpD.
J.Biomol.Nmr, 31, 2005
7L0R
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BU of 7l0r by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0P
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BU of 7l0p by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0S
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BU of 7l0s by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0Q
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BU of 7l0q by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-31
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
2A9M
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BU of 2a9m by Molmil
Structural Analysis of a Tight-binding Fluorescein-scFv; apo form
Descriptor: fluorescein-scfv heavy chain, fluorescein-scfv light chain
Authors:Cambillau, C, Spinelli, S, Honegger, A, Pluckthun, A.
Deposit date:2005-07-12
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex.
Protein Sci., 14, 2005
2A9N
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BU of 2a9n by Molmil
A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex
Descriptor: 4-(2,7-DIFLUORO-6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)ISOPHTHALIC ACID, fluorescein-scfv heavy chain, fluorescein-scfv light chain
Authors:Cambillau, C, Spinelli, S, Honegger, A, Pluckthun, A.
Deposit date:2005-07-12
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex.
Protein Sci., 14, 2005
2BKG
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BU of 2bkg by Molmil
Crystal structure of E3_19 a designed ankyrin repeat protein
Descriptor: SYNTHETIC CONSTRUCT ANKYRIN REPEAT PROTEIN E3_19
Authors:Binz, H.K, Kohl, A, Pluckthun, A, Grutter, M.G.
Deposit date:2005-02-16
Release date:2006-06-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a Consensus-Designed Ankyrin Repeat Protein: Implications for Stability
Proteins: Struct., Funct., Bioinf., 65, 2006
2BKK
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BU of 2bkk by Molmil
Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ...
Authors:Kohl, A, Amstutz, P, Parizek, P, Binz, H.K, Briand, C, Capitani, G, Forrer, P, Pluckthun, A, Grutter, M.G.
Deposit date:2005-02-16
Release date:2005-08-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein
Structure, 13, 2005
2XEH
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BU of 2xeh by Molmil
Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.
Descriptor: NI3C MUT6, SULFATE ION
Authors:Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M.
Deposit date:2010-05-14
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module.
J.Mol.Biol., 404, 2010
2XEN
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BU of 2xen by Molmil
Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.
Descriptor: 1,2-ETHANEDIOL, METHANOL, NI1C MUT4, ...
Authors:Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M.
Deposit date:2010-05-17
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module.
J.Mol.Biol., 404, 2010
2XEE
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BU of 2xee by Molmil
Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.
Descriptor: NI3C DARPIN MUTANT5
Authors:Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M.
Deposit date:2010-05-14
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module.
J.Mol.Biol., 404, 2010
4PLQ
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BU of 4plq by Molmil
Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure.
Descriptor: Arm00011
Authors:Mittl, P.R, Reichen, C, Madhurantakam, C, Pluckthun, A.
Deposit date:2014-05-19
Release date:2014-08-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure.
Protein Sci., 23, 2014
6QEV
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BU of 6qev by Molmil
EngBF DARPin Fusion 4b B6
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, MANGANESE (II) ION, PEGA domain-containing protein,PEGA domain-containing protein,EngBF DARPin fusion B6 complex, ...
Authors:Ernst, P, Pluckthun, A, Mittl, P.R.E.
Deposit date:2019-01-08
Release date:2019-11-06
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of biological targets by host:guest crystal lattice engineering.
Sci Rep, 9, 2019
6QFK
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BU of 6qfk by Molmil
EngBF DARPin Fusion 4b G10
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Ernst, P, Pluckthun, A, Mittl, P.R.E.
Deposit date:2019-01-10
Release date:2019-11-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of biological targets by host:guest crystal lattice engineering.
Sci Rep, 9, 2019
6QEP
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BU of 6qep by Molmil
EngBF DARPin Fusion 4b H14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MANGANESE (II) ION, ...
Authors:Ernst, P, Pluckthun, A, Mittl, P.R.E.
Deposit date:2019-01-08
Release date:2019-11-06
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of biological targets by host:guest crystal lattice engineering.
Sci Rep, 9, 2019
6QFO
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BU of 6qfo by Molmil
EngBF DARPin Fusion 9b 3G124
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MANGANESE (II) ION, ...
Authors:Ernst, P, Pluckthun, A, Mittl, P.R.E.
Deposit date:2019-01-10
Release date:2019-11-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of biological targets by host:guest crystal lattice engineering.
Sci Rep, 9, 2019

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