Author results

1YE3
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HORSE LIVER ALCOHOL DEHYDROGENASE APOENZYME
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Plapp, B.V., Savarimuthu, B.R., Ramaswamy, S.
Deposit date:2004-12-27
Release date:2005-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Horse Liver Alcohol Dehydrogenase Apoenzyme
To be Published
5VN1
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HORSE LIVER ALCOHOL DEHYDROGENAE COMPLEXED WITH NADH (R,S)-N-1-METHYLHEXYLFORMAMIDE
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Plapp, B.V., Ramaswamy, S., Ferraro, D.J., Baskar Raj, S.
Deposit date:2017-04-28
Release date:2017-05-10
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
6O91
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HORSE LIVER L57F ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2019-03-12
Release date:2019-04-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
6OA7
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HORSE LIVER L57F ALCOHOL DEHYDROGENASE E COMPLEXED WITH NAD AND TRIFLUOROETHANOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2019-03-15
Release date:2019-04-03
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
6OWM
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HORSE LIVER F93W ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2019-05-10
Release date:2019-05-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
6OWP
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HORSE LIVER F93W ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND TRIFLUOROETHANOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2019-05-10
Release date:2019-05-22
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
4DWV
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HORSE ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD+ AND 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Ramaswamy, S.
Deposit date:2012-02-26
Release date:2012-04-11
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes.
Biochemistry, 51, 2012
4DXH
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD+ AND 2,2,2-TRIFLUOROETHANOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Ramaswamy, S.
Deposit date:2012-02-27
Release date:2012-04-11
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes.
Biochemistry, 51, 2012
5ENV
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YEAST ALCOHOL DEHYDROGENASE WITH BOUND COENZYME
Descriptor:Alcohol dehydrogenase 1, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Plapp, B.V., Charlier Jr., H.A., Ramaswamy, S.
Deposit date:2015-11-09
Release date:2015-11-25
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanistic implications from structures of yeast alcohol dehydrogenase complexed with coenzyme and an alcohol.
Arch.Biochem.Biophys., 591, 2015
5VL0
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH NADH AND N-BENZYFORMAMIDE
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Plapp, B.V., Brown, E.N., Ramaswamy, S., Baskar Raj, S.
Deposit date:2017-04-24
Release date:2017-05-03
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
4XD2
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HORSE LIVER ALCOHOL DEHYDROGENASE-NADH COMPLEX
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Plapp, B.V., Baskar Raj, S., Ferraro, D.J.
Deposit date:2014-12-18
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of Horse liver alcohol dehydrogenase complexed with NADH
To Be Published
5VJ5
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH 1,10-PHENANTHROLINE
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, 1,10-PHENANTHROLINE
Authors:Plapp, B.V., Baskar Raj, S., Ramaswamy, S.
Deposit date:2017-04-18
Release date:2017-05-03
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
5VJG
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH 2,2'BIPYRIDINE
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, 2,2'-bipyridine
Authors:Plapp, B.V., Baskar Raj, S.
Deposit date:2017-04-19
Release date:2017-05-03
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
5VKR
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH ADENOSINE-5-DIPHOSPHORIBOSE
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Plapp, B.V., Rubach, J.K., Ramaswamy, S.
Deposit date:2017-04-22
Release date:2017-05-03
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
4W6Z
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YEAST ALCOHOL DEHYDROGENASE I, SACCHAROMYCES CEREVISIAE FERMENTATIVE ENZYME
Descriptor:Alcohol dehydrogenase 1, ZINC ION, NICOTINAMIDE-8-IODO-ADENINE-DINUCLEOTIDE, ...
Authors:plapp, B.v., savarimuthu, b.r., ramaswamy, s.
Deposit date:2014-08-21
Release date:2014-09-03
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Yeast alcohol dehydrogenase structure and catalysis.
Biochemistry, 53, 2014
3OQ6
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HORSE LIVER ALCOHOL DEHYDROGENASE A317C MUTANT COMPLEXED WITH NAD+ AND 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Herdendorf, T.J.
Deposit date:2010-09-02
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Origins of the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver A317C alcohol dehydrogenase.
Chem.Biol.Interact, 191, 2011
4NFH
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V207A HORSE LIVER ALCOHOL DEHYDROGENASE E COMPLEXED WITH NAD AND 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2013-10-31
Release date:2013-11-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis.
Biochemistry, 53, 2014
4NFS
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V203A HORSE LIVER ALCOHOL DEHYDROGENASE E COMPLEXED WITH NAD AND 2,2,2-TRIFLUOROETHANOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2013-10-31
Release date:2013-11-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis.
Biochemistry, 53, 2014
4NG5
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V203A HORSE LIVER ALCOHOL DEHYDROGENASE E COMPLEXED WITH NAD+ AND 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2013-11-01
Release date:2013-11-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis.
Biochemistry, 53, 2014
5CDG
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I220F HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Shanmuganatham, K.
Deposit date:2015-07-03
Release date:2015-07-15
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Contribution of Buried Distal Amino Acid Residues in Horse Liver Alcohol Dehydrogenase to Structure and Catalysis.
Protein Sci., 2017
5CDS
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I220L HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Shanmuganatham, K.
Deposit date:2015-07-04
Release date:2015-07-15
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Contribution of Buried Distal Amino Acid Residues in Horse Liver Alcohol Dehydrogenase to Structure and Catalysis.
Protein Sci., 2017
5CDT
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I220V HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Shanmuganatham, K.
Deposit date:2015-07-04
Release date:2015-07-15
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contribution of Buried Distal Amino Acid Residues in Horse Liver Alcohol Dehydrogenase to Structure and Catalysis.
Protein Sci., 2017
5CDU
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I220V HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PYRAZOLE
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V., Shanmuganatham, K.
Deposit date:2015-07-04
Release date:2015-07-15
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Contribution of Buried Distal Amino Acid Residues in Horse Liver Alcohol Dehydrogenase to Structure and Catalysis.
Protein Sci., 2017
5KCP
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HORSE LIVER S48T ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2016-06-06
Release date:2016-06-29
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93.
Chem. Biol. Interact., 276, 2017
5KCZ
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HORSE LIVER S48T ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND TRIFLUOROETHANOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2016-06-07
Release date:2016-06-29
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93.
Chem. Biol. Interact., 276, 2017
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