6XZC
 
 | | CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis | | Descriptor: | ESX-1 secretion-associated protein EspB | | Authors: | Piton, J, Pojer, F, Wakatsuki, S, Gati, C, Cole, S.T. | | Deposit date: | 2020-02-03 | | Release date: | 2020-06-17 | | Last modified: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | High resolution CryoEM structure of the ring-shaped virulence factor EspB fromMycobacterium tuberculosis.
J Struct Biol X, 4, 2020
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6G83
 | | Crystal structure of M. tuberculosis DprE1 in complex with sPBTZ169 (sulfonylPBTZ) | | Descriptor: | Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, [2-(4-cyclohexylsulfonylpiperazin-1-yl)-4-oxidanylidene-6-(trifluoromethyl)-1,3-benzothiazin-8-yl]-oxidanylidene-azanium | | Authors: | Piton, J, Makarov, V, Cole, S.T. | | Deposit date: | 2018-04-07 | | Release date: | 2018-08-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis.
Antimicrob. Agents Chemother., 62, 2018
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3M4I
 | | Crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 1.95 A resolution | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit B | | Authors: | Piton, J, Petrella, S, Aubry, A, Mayer, C. | | Deposit date: | 2010-03-11 | | Release date: | 2010-09-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.
Plos One, 5, 2010
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3IG0
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3IFZ
 | | crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit A, SODIUM ION | | Authors: | Piton, J, Aubry, A, Delarue, M, Mayer, C. | | Deposit date: | 2009-07-27 | | Release date: | 2010-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.
Plos One, 5, 2010
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4JZT
 | | Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) bound to GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, dGTP pyrophosphohydrolase | | Authors: | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | | Deposit date: | 2013-04-03 | | Release date: | 2013-05-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JZV
 | | Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - second guanosine residue in guanosine binding pocket | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, RNA (5'-R(*(GCP)P*G)-3'), ... | | Authors: | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | | Deposit date: | 2013-04-03 | | Release date: | 2013-05-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JZU
 | | Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - first guanosine residue in guanosine binding pocket | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA (5'-R(*(GCP)P*G)-3'), RNA PYROPHOSPHOHYDROLASE | | Authors: | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | | Deposit date: | 2013-04-03 | | Release date: | 2013-05-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JZS
 | | Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, dGTP pyrophosphohydrolase | | Authors: | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | | Deposit date: | 2013-04-03 | | Release date: | 2013-05-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5MQ8
 | | Crystal structure of Rae1 (YacP) from Bacillus subtilis | | Descriptor: | GLYCEROL, Uncharacterized protein YacP | | Authors: | Piton, J, Gilet, L, Pellegrini, O, Leroy, M, Figaro, S, Condon, C. | | Deposit date: | 2016-12-20 | | Release date: | 2017-04-19 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis.
EMBO J., 36, 2017
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5MQ9
 | | Crystal structure of Rae1 (YacP) from Bacillus subtilis (W164L mutant) | | Descriptor: | SULFATE ION, Uncharacterized protein YacP | | Authors: | Piton, J, Gilet, L, Pellegrini, O, Leroy, M, Figaro, S, Condon, C. | | Deposit date: | 2016-12-20 | | Release date: | 2017-04-19 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (3.174 Å) | | Cite: | Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis.
EMBO J., 36, 2017
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4XXX
 | | Structure of PE-PPE domains of ESX-1 secreted protein EspB, C2221 | | Descriptor: | CHLORIDE ION, ESX-1 secretion-associated protein EspB, GLYCEROL | | Authors: | Piton, J, Pojer, F, Korotkov, K.V. | | Deposit date: | 2015-01-30 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
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3T3N
 | | Molecular basis for the recognition and cleavage of RNA (UUCCGU) by the bifunctional 5'-3' exo/endoribonuclease RNase J | | Descriptor: | Metal dependent hydrolase, O2'methyl-RNA, ZINC ION | | Authors: | Dorleans, A, Li de la Sierra-Gallay, I, Piton, J, Zig, L, Gilet, L, Putzer, H, Condon, C. | | Deposit date: | 2011-07-25 | | Release date: | 2011-10-19 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Molecular Basis for the Recognition and Cleavage of RNA by the Bifunctional 5'-3' Exo/Endoribonuclease RNase J.
Structure, 19, 2011
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3T3O
 | | Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J | | Descriptor: | GLYCEROL, Metal dependent hydrolase, O2'methyl-RNA, ... | | Authors: | Dorleans, A, Li de la Sierra-Gallay, I, Piton, J, Zig, L, Gilet, L, Putzer, H, Condon, C. | | Deposit date: | 2011-07-25 | | Release date: | 2011-10-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular Basis for the Recognition and Cleavage of RNA by the Bifunctional 5'-3' Exo/Endoribonuclease RNase J.
Structure, 19, 2011
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3GKR
 | | Crystal Structure of Weissella viridescens FemX:UDP-MurNAc-hexapeptide complex | | Descriptor: | ALANINE, FemX, GLYCEROL, ... | | Authors: | Delfosse, V, Piton, J, Villet, R, Lecerf, M, Arthur, M, Mayer, C. | | Deposit date: | 2009-03-11 | | Release date: | 2010-03-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of Weissella viridescens FemX with the UDP-MurNAc-hexapeptide product of the alanine transfer reaction
To be Published
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4GCW
 | | Crystal structure of RNase Z in complex with precursor tRNA(Thr) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ribonuclease Z, TRNA(THR), ... | | Authors: | Pellegrini, O, Li de la Sierra-Gallay, I, Piton, J, Gilet, L, Condon, C. | | Deposit date: | 2012-07-31 | | Release date: | 2012-10-31 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Activation of tRNA Maturation by Downstream Uracil Residues in B. subtilis
Structure, 20, 2012
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4G3N
 | | Mycobacterium tuberculosis gyrase type IIA topoisomerase C-terminal domain at 1.4 A resolution | | Descriptor: | DNA gyrase subunit A | | Authors: | Darmon, A, Piton, J, Petrella, S, Aubry, A, Mayer, C. | | Deposit date: | 2012-07-15 | | Release date: | 2013-08-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes.
Biochem.J., 455, 2013
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6TOB
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4XWP
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4XY3
 | | Structure of ESX-1 secreted protein EspB | | Descriptor: | ESX-1 secretion-associated protein EspB | | Authors: | Wagner, J.M, Korotkov, K.V. | | Deposit date: | 2015-02-01 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.04 Å) | | Cite: | Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
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4XXN
 | | Structure of PE-PPE domains of ESX-1 secreted protein EspB, I222 | | Descriptor: | CHLORIDE ION, ESX-1 secretion-associated protein EspB, SODIUM ION | | Authors: | Korotkov, K.V. | | Deposit date: | 2015-01-30 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
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