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2VL1
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CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH A GLY-GLY PEPTIDE
Descriptor:BETA-ALANINE SYNTHASE, GLYCINE, ZINC ION
Authors:Andersen, B., Lundgren, S., Dobritzsch, D., Piskur, J.
Deposit date:2008-01-07
Release date:2008-05-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A Recruited Protease is Involved in Catabolism of Pyrimidines.
J.Mol.Biol., 379, 2008
2V8D
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CRYSTAL STRUCTURE OF MUTANT E159A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI
Descriptor:BETA-ALANINE SYNTHASE, ZINC ION
Authors:Lundgren, S., Andersen, B., Piskur, J., Dobritzsch, D.
Deposit date:2007-08-07
Release date:2007-10-02
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8G
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CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE PRODUCT BETA-ALANINE
Descriptor:BETA-ALANINE SYNTHASE, ZINC ION, BETA-ALANINE, ...
Authors:Lundgren, S., Andersen, B., Piskur, J., Dobritzsch, D.
Deposit date:2007-08-07
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8H
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CRYSTAL STRUCTURE OF MUTANT E159A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH ITS SUBSTRATE N-CARBAMYL-BETA- ALANINE
Descriptor:BETA-ALANINE SYNTHASE, ZINC ION, N-(AMINOCARBONYL)-BETA-ALANINE, ...
Authors:Lundgren, S., Andersen, B., Piskur, J., Dobritzsch, D.
Deposit date:2007-08-08
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8V
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CRYSTAL STRUCTURE OF MUTANT R322A OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI
Descriptor:BETA-ALANINE SYNTHASE, ZINC ION, N-(AMINOCARBONYL)-BETA-ALANINE, ...
Authors:Lundgren, S., Andersen, B., Piskur, J., Dobritzsch, D.
Deposit date:2007-08-15
Release date:2007-10-02
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
1R3N
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CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI
Descriptor:beta-alanine synthase, ZINC ION, BETA-AMINO ISOBUTYRATE
Authors:Lundgren, S., Gojkovic, Z., Piskur, J., Dobritzsch, D.
Deposit date:2003-10-02
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278, 2003
1R43
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CRYSTAL STRUCTURE OF BETA-ALANINE SYNTHASE FROM SACCHAROMYCES KLUYVERI (SELENOMETHIONINE SUBSTITUTED PROTEIN)
Descriptor:beta-alanine synthase, ZINC ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
Authors:Lundgren, S., Gojkovic, Z., Piskur, J., Dobritzsch, D.
Deposit date:2003-10-03
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278
1J90
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CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE
Descriptor:Deoxyribonucleoside kinase, SULFATE ION, 2'-DEOXYCYTIDINE
Authors:Johansson, K., Ramaswamy, S., Ljungkrantz, C., Knecht, W., Piskur, J., Munch-Petersen, B., Eriksson, S., Eklund, H.
Deposit date:2001-05-23
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.
Nat.Struct.Biol., 8, 2001
1OE0
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CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP
Descriptor:DEOXYRIBONUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Mikkelsen, N.E., Johansson, K., Karlsson, A., Knecht, W., Andersen, G., Piskur, J., Munch-Petersen, B., Eklund, H.
Deposit date:2003-03-17
Release date:2003-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway:Studies of the Drosophila Deoxyribonucleoside Kinase
Biochemistry, 42, 2003
1OT3
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CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOTIDE KINASE COMPLEXED WITH THE SUBSTRATE DEOXYTHYMIDINE
Descriptor:Deoxyribonucleoside Kinase, SULFATE ION, THYMIDINE
Authors:Mikkelsen, N.E., Johansson, K., Karlsson, A., Knecht, W., Andersen, G., Piskur, J., Munch-Petersen, B., Eklund, H.
Deposit date:2003-03-21
Release date:2003-05-27
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway: Studies of the Drosophila Deoxyribonucleoside Kinase.
Biochemistry, 42, 2003
1ZM7
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CRYSTAL STRUCTURE OF D. MELANOGASTER DEOXYRIBONUCLEOSIDE KINASE MUTANT N64D IN COMPLEX WITH DTTP
Descriptor:Deoxynucleoside kinase, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Welin, M., Skovgaard, T., Knecht, W., Berenstein, D., Munch-Petersen, B., Piskur, J., Eklund, H.
Deposit date:2005-05-10
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
1ZMX
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CRYSTAL STRUCTURE OF D. MELANOGASTER DEOXYRIBONUCLEOSIDE KINASE N64D MUTANT IN COMPLEX WITH THYMIDINE
Descriptor:Deoxynucleoside kinase, SULFATE ION, THYMIDINE
Authors:Welin, M., Skovgaard, T., Knecht, W., Berenstein, D., Munch-Petersen, B., Piskur, J., Eklund, H.
Deposit date:2005-05-11
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
2J9R
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THYMIDINE KINASE FROM B. ANTHRACIS IN COMPLEX WITH DT.
Descriptor:THYMIDINE KINASE, ZINC ION, THYMIDINE, ...
Authors:Kosinska, U., Carnrot, C., Sandrini, M.P.B., Clausen, A.R., Wang, L., Piskur, J., Eriksson, S., Eklund, H.
Deposit date:2006-11-15
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2JA1
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THYMIDINE KINASE FROM B. CEREUS WITH TTP BOUND AS PHOSPHATE DONOR.
Descriptor:THYMIDINE KINASE, ZINC ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Kosinska, U., Carnrot, C., Sandrini, M.P.B., Clausen, A.R., Wang, L., Piskur, J., Eriksson, S., Eklund, H.
Deposit date:2006-11-17
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2OCP
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CRYSTAL STRUCTURE OF HUMAN DEOXYGUANOSINE KINASE
Descriptor:Deoxyguanosine kinase, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
Authors:Johansson, K., Ramaswamy, S., Ljungkrantz, C., Knecht, W., Piskur, J., Munch-Petersen, B., Eriksson, S., Eklund, H.
Deposit date:2006-12-21
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Substrate Specificities of Cellular Deoxyribonucleoside Kinases.
Nat.Struct.Biol., 8, 2001
2VHH
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CRYSTAL STRUCTURE OF A PYRIMIDINE DEGRADING ENZYME FROM DROSOPHILA MELANOGASTER
Descriptor:CG3027-PA
Authors:Lundgren, S., Lohkamp, B., Andersen, B., Piskur, J., Dobritzsch, D.
Deposit date:2007-11-21
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of Beta-Alanine Synthase from Drosophila Melanogaster Reveals a Homooctameric Helical Turn-Like Assembly.
J.Mol.Biol., 377, 2008
2VHI
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CRYSTAL STRUCTURE OF A PYRIMIDINE DEGRADING ENZYME FROM DROSOPHILA MELANOGASTER
Descriptor:CG3027-PA
Authors:Lundgren, S., Lohkamp, B., Andersen, B., Piskur, J., Dobritzsch, D.
Deposit date:2007-11-21
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of Beta-Alanine Synthase from Drosophila Melanogaster Reveals a Homooctameric Helical Turn-Like Assembly.
J.Mol.Biol., 377, 2008
2VPP
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DROSOPHILA MELANOGASTER DEOXYRIBONUCLEOSIDE KINASE SUCCESSFULLY ACTIVATES GEMCITABINE IN TRANSDUCED CANCER CELL LINES
Descriptor:DEOXYNUCLEOSIDE KINASE, GEMCITABINE, SULFATE ION
Authors:Knecht, W., Mikkelsen, N.E., Clausen, A., Willer, M., Gojkovic, Z., Piskur, J.
Deposit date:2008-03-03
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Drosophila Melanogaster Deoxyribonucleoside Kinase Activates Gemcitabine.
Biochem.Biophys.Res.Commun., 382, 2009
2FTY
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CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI
Descriptor:dihydropyrimidinase, ZINC ION
Authors:Dobritzsch, D., Lohkamp, B.
Deposit date:2006-01-25
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2FVK
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CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE SUBSTRATE DIHYDROURACIL
Descriptor:dihydropyrimidinase, ZINC ION, DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE
Authors:Dobritzsch, D., Lohkamp, B.
Deposit date:2006-01-31
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2FVM
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CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM SACCHAROMYCES KLUYVERI IN COMPLEX WITH THE REACTION PRODUCT N-CARBAMYL-BETA-ALANINE
Descriptor:dihydropyrimidinase, ZINC ION, N-(AMINOCARBONYL)-BETA-ALANINE
Authors:Dobritzsch, D., Lohkamp, B.
Deposit date:2006-01-31
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2FTW
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CRYSTAL STRUCTURE OF DIHYDROPYRIMIDINASE FROM DICTYOSTELIUM DISCOIDEUM
Descriptor:dihydropyrimidine amidohydrolase, ZINC ION, MALONATE ION
Authors:Lohkamp, B., Dobritzsch, D.
Deposit date:2006-01-25
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
3QPB
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES URIDINE PHOSPHORYLASE REVEALS A SUBCLASS OF THE NP-I SUPERFAMILY
Descriptor:Uridine phosphorylase, RIBOSE-1-PHOSPHATE, URACIL
Authors:Tran, T.H., Christoffersen, S., Parker, W.B., Piskur, J., Serra, I., Terreni, M., Ealick, S.E.
Deposit date:2011-02-11
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011