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1ZMX
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Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine
Descriptor: Deoxynucleoside kinase, SULFATE ION, THYMIDINE
Authors:Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H.
Deposit date:2005-05-11
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
1ZM7
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BU of 1zm7 by Molmil
Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP
Descriptor: Deoxynucleoside kinase, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
Authors:Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H.
Deposit date:2005-05-10
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
2OCP
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BU of 2ocp by Molmil
Crystal Structure of Human Deoxyguanosine Kinase
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxyguanosine kinase
Authors:Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H.
Deposit date:2006-12-21
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Substrate Specificities of Cellular Deoxyribonucleoside Kinases.
Nat.Struct.Biol., 8, 2001
2VL1
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BU of 2vl1 by Molmil
Crystal structure of beta-alanine synthase from Saccharomyces kluyveri in complex with a gly-gly peptide
Descriptor: BETA-ALANINE SYNTHASE, GLYCINE, ZINC ION
Authors:Andersen, B, Lundgren, S, Dobritzsch, D, Piskur, J.
Deposit date:2008-01-07
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A Recruited Protease is Involved in Catabolism of Pyrimidines.
J.Mol.Biol., 379, 2008
1J90
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BU of 1j90 by Molmil
Crystal Structure of Drosophila Deoxyribonucleoside Kinase
Descriptor: 2'-DEOXYCYTIDINE, Deoxyribonucleoside kinase, SULFATE ION
Authors:Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H.
Deposit date:2001-05-23
Release date:2001-11-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.
Nat.Struct.Biol., 8, 2001
2V8D
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Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri
Descriptor: BETA-ALANINE SYNTHASE, ZINC ION
Authors:Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D.
Deposit date:2007-08-07
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8G
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Crystal structure of beta-alanine synthase from Saccharomyces kluyveri in complex with the product beta-alanine
Descriptor: BETA-ALANINE, BETA-ALANINE SYNTHASE, BICINE, ...
Authors:Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D.
Deposit date:2007-08-07
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8H
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Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri in complex with its substrate N-carbamyl-beta- alanine
Descriptor: BETA-ALANINE SYNTHASE, BICINE, N-(AMINOCARBONYL)-BETA-ALANINE, ...
Authors:Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D.
Deposit date:2007-08-08
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8V
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Crystal structure of mutant R322A of beta-alanine synthase from Saccharomyces kluyveri
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-ALANINE SYNTHASE, N-(AMINOCARBONYL)-BETA-ALANINE, ...
Authors:Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D.
Deposit date:2007-08-15
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
1R3N
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BU of 1r3n by Molmil
Crystal structure of beta-alanine synthase from Saccharomyces kluyveri
Descriptor: BETA-AMINO ISOBUTYRATE, ZINC ION, beta-alanine synthase
Authors:Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D.
Deposit date:2003-10-02
Release date:2003-11-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278, 2003
1R43
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BU of 1r43 by Molmil
Crystal structure of beta-alanine synthase from Saccharomyces kluyveri (selenomethionine substituted protein)
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-AMINO ISOBUTYRATE, ...
Authors:Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D.
Deposit date:2003-10-03
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278
2JA1
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Thymidine kinase from B. cereus with TTP bound as phosphate donor.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H.
Deposit date:2006-11-17
Release date:2007-01-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
2J9R
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BU of 2j9r by Molmil
Thymidine kinase from B. anthracis in complex with dT.
Descriptor: PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ...
Authors:Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H.
Deposit date:2006-11-15
Release date:2007-01-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
1OE0
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BU of 1oe0 by Molmil
CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP
Descriptor: DEOXYRIBONUCLEOSIDE KINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
Authors:Mikkelsen, N.E, Johansson, K, Karlsson, A, Knecht, W, Andersen, G, Piskur, J, Munch-Petersen, B, Eklund, H.
Deposit date:2003-03-17
Release date:2003-10-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway:Studies of the Drosophila Deoxyribonucleoside Kinase
Biochemistry, 42, 2003
1OT3
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BU of 1ot3 by Molmil
Crystal structure of Drosophila deoxyribonucleotide kinase complexed with the substrate deoxythymidine
Descriptor: Deoxyribonucleoside Kinase, SULFATE ION, THYMIDINE
Authors:Mikkelsen, N.E, Johansson, K, Karlsson, A, Knecht, W, Andersen, G, Piskur, J, Munch-Petersen, B, Eklund, H.
Deposit date:2003-03-21
Release date:2003-05-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway: Studies of the Drosophila Deoxyribonucleoside Kinase.
Biochemistry, 42, 2003
2VHH
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BU of 2vhh by Molmil
Crystal structure of a pyrimidine degrading enzyme from Drosophila melanogaster
Descriptor: CG3027-PA
Authors:Lundgren, S, Lohkamp, B, Andersen, B, Piskur, J, Dobritzsch, D.
Deposit date:2007-11-21
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of Beta-Alanine Synthase from Drosophila Melanogaster Reveals a Homooctameric Helical Turn-Like Assembly.
J.Mol.Biol., 377, 2008
2VHI
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BU of 2vhi by Molmil
Crystal structure of a pyrimidine degrading enzyme from Drosophila melanogaster
Descriptor: CG3027-PA
Authors:Lundgren, S, Lohkamp, B, Andersen, B, Piskur, J, Dobritzsch, D.
Deposit date:2007-11-21
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of Beta-Alanine Synthase from Drosophila Melanogaster Reveals a Homooctameric Helical Turn-Like Assembly.
J.Mol.Biol., 377, 2008
2VPP
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Drosophila melanogaster deoxyribonucleoside kinase successfully activates gemcitabine in transduced cancer cell lines
Descriptor: DEOXYNUCLEOSIDE KINASE, GEMCITABINE, SULFATE ION
Authors:Knecht, W, Mikkelsen, N.E, Clausen, A, Willer, M, Gojkovic, Z, Piskur, J.
Deposit date:2008-03-03
Release date:2009-03-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Drosophila Melanogaster Deoxyribonucleoside Kinase Activates Gemcitabine.
Biochem.Biophys.Res.Commun., 382, 2009
2FTY
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BU of 2fty by Molmil
Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri
Descriptor: ZINC ION, dihydropyrimidinase
Authors:Dobritzsch, D, Lohkamp, B.
Deposit date:2006-01-25
Release date:2006-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2FVK
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Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the substrate dihydrouracil
Descriptor: DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, ZINC ION, dihydropyrimidinase
Authors:Dobritzsch, D, Lohkamp, B.
Deposit date:2006-01-31
Release date:2006-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2FVM
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Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the reaction product N-carbamyl-beta-alanine
Descriptor: N-(AMINOCARBONYL)-BETA-ALANINE, ZINC ION, dihydropyrimidinase
Authors:Dobritzsch, D, Lohkamp, B.
Deposit date:2006-01-31
Release date:2006-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2FTW
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Crystal structure of dihydropyrimidinase from dictyostelium discoideum
Descriptor: MALONATE ION, ZINC ION, dihydropyrimidine amidohydrolase
Authors:Lohkamp, B, Dobritzsch, D.
Deposit date:2006-01-25
Release date:2006-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
3QPB
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Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily
Descriptor: 1-O-phosphono-alpha-D-ribofuranose, URACIL, Uridine phosphorylase
Authors:Tran, T.H, Christoffersen, S, Parker, W.B, Piskur, J, Serra, I, Terreni, M, Ealick, S.E.
Deposit date:2011-02-11
Release date:2011-08-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011

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