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3D5K
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BU of 3d5k by Molmil
Crystal structure of the OprM channel in a non-symmetrical space group
Descriptor: CHLORIDE ION, Outer membrane protein oprM, SODIUM ION
Authors:Phan, G, Broutin, I, Ducruix, A.
Deposit date:2008-05-16
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and dynamical insights into the opening mechanism of P. aeruginosa OprM channel.
Structure, 18, 2010
3RFZ
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BU of 3rfz by Molmil
Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate
Descriptor: Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ...
Authors:Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G.
Deposit date:2011-04-07
Release date:2011-06-01
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
5NSW
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BU of 5nsw by Molmil
Xenon for tunnelling analysis of the efflux pump component OprN.
Descriptor: Multidrug efflux outer membrane protein OprN, NICKEL (II) ION, PALMITIC ACID, ...
Authors:Phan, G, Prange, T, Enguene Ntsogo, Y.V, Garnier, C, Ducruix, A, Broutin, I.
Deposit date:2017-04-27
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Xenon for tunnelling analysis of the efflux pump component OprN.
PLoS ONE, 12, 2017
2XG4
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BU of 2xg4 by Molmil
E. coli P pilus chaperone-subunit complex PapD-PapH bound to pilus biogenesis inhibitor, pilicide 2c
Descriptor: (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, CHAPERONE PROTEIN PAPD, COBALT (II) ION, ...
Authors:Remaut, H, Phan, G, Buelens, F, Chorell, E, Pinkner, J.S, Edvinsson, S, Almqvist, F, Hultgren, S.J, Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
2XG5
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BU of 2xg5 by Molmil
E. coli P pilus chaperone-subunit complex PapD-PapH bound to pilus biogenesis inhibitor, pilicide 5d
Descriptor: (2R)-2-[5-CYCLOPROPYL-6-(HYDROXYSULFANYL)-4-(NAPHTHALEN-1-YLMETHYL)-2-OXOPYRIDIN-1(2H)-YL]-3-PHENYLPROPANOIC ACID, (2R,3R)-8-CYCLOPROPYL-7-(NAPHTHALEN-1-YLMETHYL)-5-OXO-2-PHENYL-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, CHAPERONE PROTEIN PAPD, ...
Authors:Remaut, H, Phan, G, Buelens, F, Chorell, E, Pinkner, J.S, Edvinsson, S, Almqvist, F, Hultgren, S.J, Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
5IUY
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BU of 5iuy by Molmil
Structural insights of the outer-membrane channel OprN
Descriptor: CHLORIDE ION, FORMIC ACID, Multidrug efflux outer membrane protein OprN, ...
Authors:Ntsogo, Y, Garnier, C, Phan, G, Monlezun, L, Benas, P, Broutin, I.
Deposit date:2016-03-18
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Xenon for tunnelling analysis of the efflux pump component OprN.
PLoS ONE, 12, 2017
6ZRE
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BU of 6zre by Molmil
Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
Descriptor: Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ...
Authors:Ntsogo Enguene, Y.V, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I.
Deposit date:2020-07-13
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa.
To Be Published
7AKZ
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BU of 7akz by Molmil
Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
Descriptor: Outer membrane protein OprM, PALMITIC ACID, octyl beta-D-glucopyranoside
Authors:Ntsogo Enguene, V.Y, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I.
Deposit date:2020-10-02
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa
To Be Published
4Y1K
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BU of 4y1k by Molmil
PALMITOYLATED OPRM OUTER MEMBRANE FACTOR
Descriptor: Outer membrane protein OprM, PALMITIC ACID
Authors:Monlezun, L, Phan, G, Broutin, I.
Deposit date:2015-02-07
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:New OprM structure highlighting the nature of the N-terminal anchor.
Front Microbiol, 6, 2015
6T7S
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BU of 6t7s by Molmil
MexB structure solved by cryo-EM in nanodisc in absence of its protein partners
Descriptor: Efflux pump membrane transporter
Authors:Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I.
Deposit date:2019-10-23
Release date:2020-09-16
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
6TA6
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BU of 6ta6 by Molmil
MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs
Descriptor: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM
Authors:Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I.
Deposit date:2019-10-29
Release date:2020-09-16
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
6TA5
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BU of 6ta5 by Molmil
OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs
Descriptor: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM
Authors:Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I.
Deposit date:2019-10-29
Release date:2020-09-16
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
8Q8O
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BU of 8q8o by Molmil
PA14_16140 protein: the regulator of an operon involved in the biofilm formation in PA14 P. aeruginosa
Descriptor: DUF2170 family protein, GLYCEROL, Tb-Xo4
Authors:Broutin, I, Phan, G, Girard, E.
Deposit date:2023-08-18
Release date:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:BacA: a possible regulator that contributes to the biofilm formation of Pseudomonas aeruginosa
Front Microbiol, 2024
3OHN
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BU of 3ohn by Molmil
Crystal structure of the FimD translocation domain
Descriptor: Outer membrane usher protein FimD
Authors:Wang, T, Li, H.
Deposit date:2010-08-17
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.011 Å)
Cite:Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011

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