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1EL2
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SOLUTION STRUCTURE OF A MODIFIED HUMAN TELOMERE FRAGMENT (STRUCTURE "A")
Descriptor:5'-D(*CP*CP*CP*TP*AP*AP*(5CM)P*CP*CP*TP*AP*AP*CP*CP*CP*UP*AP*AP*CP*CP*CP*T)-3'
Authors:Phan, A.T., Gueron, M., Leroy, J.-L.
Deposit date:2000-03-13
Release date:2000-03-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure and internal motions of a fragment of the cytidine-rich strand of the human telomere.
J.Mol.Biol., 299, 2000
1ELN
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SOLUTION STRUCTURE OF A MODIFIED HUMAN TELOMERE FRAGMENT (STRUCTURE "S")
Descriptor:5'-D(*CP*CP*CP*TP*AP*AP*(5CM)P*CP*CP*TP*AP*AP*CP*CP*CP*UP*AP*AP*CP*CP*CP*T)-3'
Authors:Phan, A.T., Gueron, M., Leroy, J.-L.
Deposit date:2000-03-14
Release date:2000-03-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure and internal motions of a fragment of the cytidine-rich strand of the human telomere.
J.Mol.Biol., 299, 2000
1Y8D
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DIMERIC PARALLEL-STRANDED TETRAPLEX WITH 3+1 5' G-TETRAD INTERFACE, SINGLE-RESIDUE CHAIN REVERSAL LOOPS AND GAG TRIAD IN THE CONTEXT OF A(GGGG) PENTAD
Descriptor:5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*GP*T)-3'
Authors:Phan, A.T., Kuryavyi, V.V., Ma, J.-B., Faure, A., Andreola, M.-L., Patel, D.J.
Deposit date:2004-12-11
Release date:2005-02-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:An interlocked dimeric parallel-stranded DNA quadruplex: A potent inhibitor of HIV-1 integrase
Proc.Natl.Acad.Sci.USA, 102, 2005
2A5P
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MONOMERIC PARALLEL-STRANDED DNA TETRAPLEX WITH SNAP-BACK 3+1 3' G-TETRAD, SINGLE-RESIDUE CHAIN REVERSAL LOOPS, GAG TRIAD IN THE CONTEXT OF GAAG DIAGONAL LOOP, NMR, 8 STRUCT.
Descriptor:5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'
Authors:Phan, A.T., Kuryavyi, V.V., Gaw, H.Y., Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2A5R
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COMPLEX OF TETRA-(4-N-METHYLPYRIDYL) PORPHIN WITH MONOMERIC PARALLEL-STRANDED DNA TETRAPLEX, SNAP-BACK 3+1 3' G-TETRAD, SINGLE-RESIDUE CHAIN REVERSAL LOOPS, GAG TRIAD IN THE CONTEXT OF GAAG DIAGONAL LOOP, C-MYC PROMOTER, NMR, 6 STRUCT.
Descriptor:5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3', (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin
Authors:Phan, A.T., Kuryavyi, V.V., Gaw, H.Y., Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2O3M
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MONOMERIC G-DNA TETRAPLEX FROM HUMAN C-KIT PROMOTER
Descriptor:5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'
Authors:Phan, A.T., Kuryavyi, V.V., Burge, S., Neidle, S., Patel, D.J.
Deposit date:2006-12-01
Release date:2007-05-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
J.Am.Chem.Soc., 129, 2007
2JSK
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, 16 G FORM 1, NMR, 10 STRUCTURES
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-07
Release date:2008-07-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2JSL
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, FORM 2 NATURAL, NMR, 10 STRUCTURES
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-08
Release date:2008-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2JSM
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, FORM 1 NATURAL
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-09
Release date:2008-07-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution
Nucleic Acids Res., 35, 2007
2JSQ
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, FORM 2 15BRG, NMR, 10 STRUCTURES
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-11
Release date:2008-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2KBP
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SOLUTION STRUCTURE OF A G-QUADRUPLEX OF HUMAN TELOMERIC RNA
Descriptor:5'-R(*UP*AP*GP*GP*GP*UP*UP*AP*GP*GP*GP*U)-3'
Authors:Phan, A.T., Martadinata, H.
Deposit date:2008-12-05
Release date:2009-03-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution.
J.Am.Chem.Soc., 131, 2009
6H1K
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THE MAJOR G-QUADRUPLEX FORM OF HIV-1 LTR
Descriptor:DNA (28-MER)
Authors:Phan, A.T., Heddi, B., Butovskaya, E., Bakalar, B., Richter, S.N.
Deposit date:2018-07-11
Release date:2018-10-17
Last modified:2018-11-07
Method:SOLUTION NMR
Cite:Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop.
J. Am. Chem. Soc., 140, 2018
1YKQ
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CRYSTAL STRUCTURE OF DIELS-ALDER RIBOZYME
Descriptor:Diels-Alder ribozyme, CADMIUM ION, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKV
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CRYSTAL STRUCTURE OF THE DIELS-ALDER RIBOZYME COMPLEXED WITH THE PRODUCT OF THE REACTION BETWEEN N-PENTYLMALEIMIDE AND COVALENTLY ATTACHED 9-HYDROXYMETHYLANTHRACENE
Descriptor:Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YLS
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CRYSTAL STRUCTURE OF SELENIUM-MODIFIED DIELS-ALDER RIBOZYME COMPLEXED WITH THE PRODUCT OF THE REACTION BETWEEN N-PENTYLMALEIMIDE AND COVALENTLY ATTACHED 9-HYDROXYMETHYLANTHRACENE
Descriptor:RNA Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-19
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YTY
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STRUCTURAL BASIS FOR RECOGNITION OF UUUOH 3'-TERMINII OF NASCENT RNA POL III TRANSCRIPTS BY LA AUTOANTIGEN
Descriptor:5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein
Authors:Teplova, M., Yuan, Y.R., Ilin, S., Malinina, L., Phan, A.T., Teplov, A., Patel, D.J.
Deposit date:2005-02-11
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Mol.Cell, 21, 2006
1ZH5
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STRUCTURAL BASIS FOR RECOGNITION OF UUUOH 3'-TERMINII OF NASCENT RNA POL III TRANSCRIPTS BY LA AUTOANTIGEN
Descriptor:5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein, SULFATE ION
Authors:Teplova, M., Yuan, Y.R., Ilin, S., Malinina, L., Phan, A.T., Teplov, A., Patel, D.J.
Deposit date:2005-04-22
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Mol.Cell, 21, 2006
2AQY
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(3+1) ASSEMBLY OF THREE HUMAN TELOMERIC DNA REPEATS INTO AN ASYMMETRICAL DIMERIC G-QUADRUPLEX
Descriptor:5'-D(*GP*(OIP)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3', 5'-D(*TP*AP*GP*GP*GP*(DU))-3'
Authors:Zhang, N., Phan, A.T., Patel, D.J.
Deposit date:2005-08-18
Release date:2006-03-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex
J.Am.Chem.Soc., 127, 2005
2GKU
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 12 STRUCTURES
Descriptor:Human telomere DNA
Authors:Luu, K.N., Phan, A.T., Kuryavyi, V.V., Lacroix, L., Patel, D.J.
Deposit date:2006-04-03
Release date:2006-08-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold.
J.Am.Chem.Soc., 128, 2006
2KF7
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STRUCTURE OF A TWO-G-TETRAD BASKET-TYPE INTRAMOLECULAR G-QUADRUPLEX FORMED BY HUMAN TELOMERIC REPEATS IN K+ SOLUTION (WITH G7-TO-BRG SUBSTITUTION)
Descriptor:HUMAN TELOMERE DNA
Authors:Lim, K.W., Amrane, S., Bouaziz, S., Xu, W., Mu, Y., Patel, D.J., Luu, K.N., Phan, A.T.
Deposit date:2009-02-12
Release date:2009-03-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
2KF8
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STRUCTURE OF A TWO-G-TETRAD BASKET-TYPE INTRAMOLECULAR G-QUADRUPLEX FORMED BY HUMAN TELOMERIC REPEATS IN K+ SOLUTION
Descriptor:HUMAN TELOMERE DNA
Authors:Lim, K.W., Amrane, S., Bouaziz, S., Xu, W., Mu, Y., Patel, D.J., Luu, K.N., Phan, A.T.
Deposit date:2009-02-12
Release date:2009-03-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
2KM3
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STRUCTURE OF AN INTRAMOLECULAR G-QUADRUPLEX CONTAINING A G.C.G.C TETRAD FORMED BY HUMAN TELOMERIC VARIANT CTAGGG REPEATS
Descriptor:DNA (5'-D(*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*GP*CP*TP*AP*GP*GP*G)-3')
Authors:Lim, K.W., Alberti, P., Guedin, A., Lacroix, L., Riou, J.F., Royle, N.J., Mergny, J.L., Phan, A.T.
Deposit date:2009-07-17
Release date:2009-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad
Nucleic Acids Res., 37, 2009
2KOW
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STRUCTURE OF A TWO-G-TETRAD BASKET-TYPE INTRAMOLECULAR G-QUADRUPLEX FORMED BY GIARDIA TELOMERIC REPEAT D(TAGGG)4 IN K+ SOLUTION (WITH G18-TO-INO SUBSTITUTION)
Descriptor:DNA (5'-D(*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*IP*GP*G)-3')
Authors:Hu, L., Lim, K.W., Bouaziz, S., Phan, A.T.
Deposit date:2009-10-02
Release date:2009-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Giardia Telomeric Sequence d(TAGGG)(4) Forms Two Intramolecular G-Quadruplexes in K(+) Solution: Effect of Loop Length and Sequence on the Folding Topology.
J.Am.Chem.Soc., 131, 2009
2KYO
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DIMERIC HUMAN CKIT-2 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA NMR, 10 STRUCTURES
Descriptor:5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
Authors:Kuryavyi, V., Phan, A.T., Patel, D.J.
Deposit date:2010-06-05
Release date:2010-06-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
2KYP
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MONOMERIC HUMAN CKIT-2 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA NMR, 12 STRUCTURES
Descriptor:5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
Authors:Kuryavyi, V., Phan, A.T., Patel, D.J.
Deposit date:2010-06-06
Release date:2010-06-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
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