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1C8M
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REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS
Descriptor:HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION, 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE
Authors:Chakravarty, S., Bator, C.M., Pevear, D.C., Diana, G.D., Rossmann, M.G.
Deposit date:2000-05-26
Release date:2000-11-22
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:THE REFINED STRUCTURE OF A PICORNAVIRUS INHIBITOR CURRENTLY IN CLINICAL TRIALS, WHEN COMPLEXED WITH HUMAN RHINOVIRUS 16
to be published
1S48
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CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 1 (RESIDUES 71-679) FROM BVDV
Descriptor:RNA-dependent RNA polymerase
Authors:Choi, K.H., Groarke, J.M., Young, D.C., Kuhn, R.J., Smith, J.L., Pevear, D.C., Rossmann, M.G.
Deposit date:2004-01-15
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1S49
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CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 1 (RESIDUES 71-679) FROM BOVINE VIRAL DIARRHEA VIRUS COMPLEXED WITH GTP
Descriptor:RNA-dependent RNA polymerase, GUANOSINE-5'-TRIPHOSPHATE
Authors:Choi, K.H., Groarke, J.M., Young, D.C., Kuhn, R.J., Smith, J.L., Pevear, D.C., Rossmann, M.G.
Deposit date:2004-01-15
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1S4F
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CRYSTAL STRUCTURE OF RNA-DEPENDENT RNA POLYMERASE CONSTRUCT 2 FROM BOVINE VIRAL DIARRHEA VIRUS (BVDV)
Descriptor:RNA-dependent RNA polymerase
Authors:Choi, K.H., Groarke, J.M., Young, D.C., Kuhn, R.J., Smith, J.L., Pevear, D.C., Rossmann, M.G.
Deposit date:2004-01-16
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1NA1
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THE STRUCTURE OF HRV14 WHEN COMPLEXED WITH PLECONARIL
Descriptor:Coat protein VP1, Coat protein VP2, Coat protein VP3, ...
Authors:Zhang, Y., Simpson, A.A., Bator, C.M., Chakravarty, S., Pevear, D.C., Skochko, G.A., Tull, T.M., Diana, G., Rossmann, M.G.
Deposit date:2002-11-26
Release date:2003-12-16
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
1NCQ
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THE STRUCTURE OF HRV14 WHEN COMPLEXED WITH PLECONARIL, AN ANTIVIRAL COMPOUND
Descriptor:COAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ...
Authors:Zhang, Y., Simpson, A.A., Bator, C.M., Chakravarty, S., Pevear, D.C., Skochko, G.A., Tull, T.M., Diana, G., Rossmann, M.G.
Deposit date:2002-12-05
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
1NCR
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THE STRUCTURE OF RHINOVIRUS 16 WHEN COMPLEXED WITH PLECONARIL, AN ANTIVIRAL COMPOUND
Descriptor:coat protein VP1, coat protein VP2, coat protein VP3, ...
Authors:Zhang, Y., Simpson, A.A., Bator, C.M., Chakravarty, S., Pevear, D.C., Skochko, G.A., Tull, T.M., Diana, G., Rossmann, M.G.
Deposit date:2002-12-05
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
1ND2
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THE STRUCTURE OF RHINOVIRUS 16
Descriptor:coat protein VP1, coat protein VP2, coat protein VP3, ...
Authors:Zhang, Y., Simpson, A.A., Bator, C.M., Chakravarty, S., Pevear, D.C., Skochko, G.A., Tull, T.M., Diana, G., Rossmann, M.G.
Deposit date:2002-12-06
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
1ND3
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THE STRUCTURE OF HRV16, WHEN COMPLEXED WITH PLECONARIL, AN ANTIVIRAL COMPOUND
Descriptor:coat protein VP1, coat protein VP2, coat protein VP3, ...
Authors:Zhang, Y., Simpson, A.A., Bator, C.M., Chakravarty, S., Pevear, D.C., Skochko, G.A., Tull, T.M., Diana, G., Rossmann, M.G.
Deposit date:2002-12-06
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
J.Virol., 78, 2004
1RUC
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RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
Descriptor:RHINOVIRUS 14, 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUD
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RHINOVIRUS 14 MUTANT N1105S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
Descriptor:RHINOVIRUS 14, 5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUE
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RHINOVIRUS 14 SITE DIRECTED MUTANT N1219A COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
Descriptor:RHINOVIRUS 14, 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUF
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RHINOVIRUS 14 (HRV14) (MUTANT WITH ASN 1 219 REPLACED BY ALA (N219A IN CHAIN 1)
Descriptor:RHINOVIRUS 14
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUG
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RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52035
Descriptor:RHINOVIRUS 14, 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUH
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RHINOVIRUS 14 MUTANT N1219S COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
Descriptor:RHINOVIRUS 14, 5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUI
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RHINOVIRUS 14 MUTANT S1223G COMPLEXED WITH ANTIVIRAL COMPOUND WIN 52084
Descriptor:RHINOVIRUS 14, 5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1RUJ
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RHINOVIRUS 14 MUTANT WITH SER 1 223 REPLACED BY GLY (S1223G)
Descriptor:RHINOVIRUS 14
Authors:Hadfield, A., Oliveira, M.A., Kim, K.H., Minor, I., Kremer, M.J., Heinz, B.A., Shepard, D., Pevear, D.C., Rueckert, R.R., Rossmann, M.G.
Deposit date:1995-06-09
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
J.Mol.Biol., 253, 1995
1AYN
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HUMAN RHINOVIRUS 16 COAT PROTEIN
Descriptor:HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION, LAURIC ACID, ...
Authors:Hadfield, A.T., Oliveira, M.A., Zhao, R., Rossmann, M.G.
Deposit date:1997-11-06
Release date:1998-01-21
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of human rhinovirus 16.
Structure, 1, 1993
1RHI
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HUMAN RHINOVIRUS 3 COAT PROTEIN
Descriptor:HUMAN RHINOVIRUS 3 COAT PROTEIN, CALCIUM ION
Authors:Zhao, R., Rossmann, M.G.
Deposit date:1996-06-17
Release date:1997-03-12
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human rhinovirus 3 at 3.0 A resolution.
Structure, 4, 1996
1AYM
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HUMAN RHINOVIRUS 16 COAT PROTEIN AT HIGH RESOLUTION
Descriptor:HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION, LAURIC ACID, ...
Authors:Hadfield, A.T., Rossmann, M.G.
Deposit date:1997-11-06
Release date:1998-01-21
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The refined structure of human rhinovirus 16 at 2.15 A resolution: implications for the viral life cycle.
Structure, 5, 1997
1QJU
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HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND VP61209
Descriptor:PROTEIN VP1, PROTEIN VP2, PROTEIN VP3, ...
Authors:Hadfield, A.T., Minor, I., Diana, G.D., Rossmann, M.G.
Deposit date:1999-07-05
Release date:1999-07-20
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of Three Structurally Related Antiviral Compounds in Complex with Human Rhinovirus 16
Proc.Natl.Acad.Sci.USA, 96, 1999
1QJX
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HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND WIN68934
Descriptor:PROTEIN VP1, PROTEIN VP2, PROTEIN VP3, ...
Authors:Hadfield, A.T., Diana, G.D., Rossmann, M.G.
Deposit date:1999-07-06
Release date:1999-07-20
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of Three Structurally Related Antiviral Compounds in Complex with Human Rhinovirus 16
Proc.Natl.Acad.Sci.USA, 96, 1999
1QJY
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HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND VP65099
Descriptor:PROTEIN VP1, PROTEIN VP2, PROTEIN VP3, ...
Authors:Hadfield, A.T., Diana, G.D., Rossmann, M.G.
Deposit date:1999-07-06
Release date:1999-07-20
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of Three Structurally Related Antiviral Compounds in Complex with Human Rhinovirus 16
Proc.Natl.Acad.Sci.USA, 96, 1999
2HWB
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Kim, K.H., Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
2HWC
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A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
Descriptor:HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3), ...
Authors:Kim, K.H., Rossmann, M.G.
Deposit date:1994-01-25
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993
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