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1DVQ
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
Descriptor:TRANSTHYRETIN
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-22
Release date:2001-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVS
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH RESVERATROL
Descriptor:TRANSTHYRETIN, RESVERATROL
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-22
Release date:2001-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVT
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH FLURBIPROFEN
Descriptor:TRANSTHYRETIN, FLURBIPROFEN
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-22
Release date:2001-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVU
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DIBENZOFURAN-4,6-DICARBOXYLIC ACID
Descriptor:TRANSTHYRETIN, DIBENZOFURAN-4,6-DICARBOXYLIC ACID
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-22
Release date:2001-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVX
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DICLOFENAC
Descriptor:TRANSTHYRETIN, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-23
Release date:2001-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVY
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CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH N-(M-TRIFLUOROMETHYLPHENYL) PHENOXAZINE-4,6-DICARBOXYLIC ACID
Descriptor:TRANSTHYRETIN, N-(M-TRIFLUOROMETHYLPHENYL) PHENOXAZINE-4,6-DICARBOXYLIC ACID
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-23
Release date:2001-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVZ
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID
Descriptor:TRANSTHYRETIN, O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID
Authors:Klabunde, T., Petrassi, H.M., Oza, V.B., Kelly, J.W., Sacchettini, J.C.
Deposit date:2000-01-23
Release date:2001-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1GKO
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AN ENGINEERED TRANSTHYRETIN MONOMER THAT IS NON-AMYLOIDOGENIC - UNLESS PARTIALLY DENATURED
Descriptor:TRANSTHYRETIN
Authors:Jiang, X., Smith, C.S., Petrassi, H.M., Hammarstrom, P., White, J.T., Sacchettini, J.C., Kelly, J.W.
Deposit date:2001-08-17
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An Engineered Transthyretin Monomer that is Nonamyloidogenic, Unless It is Partially Denatured
Biochemistry, 40, 2001
3E0P
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THE X-RAY STRUCTURE OF HUMAN PROSTASIN IN COMPLEX WITH A COVALENT BENZOXAZOLE INHIBITOR
Descriptor:Prostasin, benzyl [(1R)-1-({(2S,4R)-2-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-4-[(4-methylbenzyl)oxy]pyrrolidin-1-yl}carbonyl)-3-phenylpropyl]carbamate, GLYCEROL
Authors:Spraggon, G., Hornsby, M., Shipway, A., Harris, J.L., Lesley, S.A.
Deposit date:2008-07-31
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.
Bioorg.Med.Chem.Lett., 18, 2008
3E16
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X-RAY STRUCTURE OF HUMAN PROSTASIN IN COMPLEX WITH BENZOXAZOLE WARHEAD PEPTIDOMIMIC, LYSINE IN P3
Descriptor:Prostasin, GLYCEROL, benzyl [(1S)-5-amino-1-{[(1S)-1-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-3-phenylpropyl]carbamoyl}pentyl]carbamate, ...
Authors:Spraggon, G., Hornsby, M., Shipway, A., Harris, J.L., Lesley, S.A.
Deposit date:2008-08-01
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.
Bioorg.Med.Chem.Lett., 18, 2008