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1D7Q
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HUMAN TRANSLATION INITIATION FACTOR EIF1A
Descriptor:PROTEIN (N-TERMINAL HISTIDINE TAG), TRANSLATION INITIATION FACTOR 1A
Authors:Battiste, J.L., Pestova, T.V., Hellen, C.U.T., Wagner, G.
Deposit date:1999-10-19
Release date:2000-03-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The eIF1A solution structure reveals a large RNA-binding surface important for scanning function.
Mol.Cell, 5, 2000
1HU3
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MIDDLE DOMAIN OF HUMAN EIF4GII
Descriptor:EIF4GII
Authors:Marcotrigiano, J., Lomakin, I., Pestova, T.V., Hellen, C.U.T., Sonenberg, N., Burley, S.K.
Deposit date:2001-01-03
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.
Mol.Cell, 7, 2001
2IF1
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HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
Descriptor:EIF1
Authors:Fletcher, C.M., Hellen, C.U.T., Pestova, T.V., Wagner, G.
Deposit date:1998-08-04
Release date:1999-05-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and interactions of the translation initiation factor eIF1.
EMBO J., 18, 1999
3J5Y
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STRUCTURE OF THE MAMMALIAN RIBOSOMAL PRE-TERMINATION COMPLEX ASSOCIATED WITH ERF1-ERF3-GDPNP
Descriptor:Eukaryotic peptide chain release factor subunit 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', ...
Authors:des Georges, A., Hashem, Y., Unbehaun, A., Grassucci, R.A., Taylor, D., Hellen, C.U.T., Pestova, T.V., Frank, J.
Deposit date:2013-11-21
Release date:2013-12-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
4C4Q
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CRYO-EM MAP OF THE CSFV IRES IN COMPLEX WITH THE SMALL RIBOSOMAL 40S SUBUNIT AND DHX29
Descriptor:INTERNAL RIBOSOMAL ENTRY SITE
Authors:Hashem, Y., desGeorges, A., Dhote, V., Langlois, R., Liao, H.Y., Grassucci, R.A., Pestova, T.V., Hellen, C.U.T., Frank, J.
Deposit date:2013-09-07
Release date:2013-10-30
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Hepatitis-C-Virus-Like Internal Ribosome Entry Sites Displace Eif3 to Gain Access to the 40S Subunit
Nature, 503, 2013
4D5L
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CRYO-EM STRUCTURES OF RIBOSOMAL 80S COMPLEXES WITH TERMINATION FACTORS AND CRICKET PARALYSIS VIRUS IRES REVEAL THE IRES IN THE TRANSLOCATED STATE
Descriptor:18S RRNA 2, 40S RIBOSOMAL PROTEIN ES26, 40S RIBOSOMAL PROTEIN ES27, ...
Authors:Muhs, M., Hilal, T., Mielke, T., Skabkin, M.A., Sanbonmatsu, K.Y., Pestova, T.V., Spahn, C.M.T.
Deposit date:2014-11-05
Release date:2015-02-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5N
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CRYO-EM STRUCTURES OF RIBOSOMAL 80S COMPLEXES WITH TERMINATION FACTORS AND CRICKET PARALYSIS VIRUS IRES REVEAL THE IRES IN THE TRANSLOCATED STATE
Descriptor:EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1, CRICKET PARALYSIS VIRUS IRES RNA
Authors:Muhs, M., Hilal, T., Mielke, T., Skabkin, M.A., Sanbonmatsu, K.Y., Pestova, T.V., Spahn, C.M.T.
Deposit date:2014-11-06
Release date:2015-02-04
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5Y
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CRYO-EM STRUCTURES OF RIBOSOMAL 80S COMPLEXES WITH TERMINATION FACTORS AND CRICKET PARALYSIS VIRUS IRES REVEAL THE IRES IN THE TRANSLOCATED STATE
Descriptor:60S RIBOSOMAL PROTEIN UL2, 60S RIBOSOMAL PROTEIN UL3, 60S RIBOSOMAL PROTEIN UL4, ...
Authors:Muhs, M., Hilal, T., Mielke, T., Skabkin, M.A., Sanbonmatsu, K.Y., Pestova, T.V., Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
4D61
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CRYO-EM STRUCTURES OF RIBOSOMAL 80S COMPLEXES WITH TERMINATION FACTORS AND CRICKET PARALYSIS VIRUS IRES REVEAL THE IRES IN THE TRANSLOCATED STATE
Descriptor:18S RRNA, 40S RIBOSOMAL PROTEIN SA, 40S RIBOSOMAL PROTEIN S3A, ...
Authors:Muhs, M., Hilal, T., Mielke, T., Skabkin, M.A., Sanbonmatsu, K.Y., Pestova, T.V., Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D67
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CRYO-EM STRUCTURES OF RIBOSOMAL 80S COMPLEXES WITH TERMINATION FACTORS AND CRICKET PARALYSIS VIRUS IRES REVEAL THE IRES IN THE TRANSLOCATED STATE
Descriptor:60S RIBOSOMAL PROTEIN L8, 60S RIBOSOMAL PROTEIN L3, 60S RIBOSOMAL PROTEIN L4, ...
Authors:Muhs, M., Hilal, T., Mielke, T., Skabkin, M.A., Sanbonmatsu, K.Y., Pestova, T.V., Spahn, C.M.T.
Deposit date:2014-11-10
Release date:2015-03-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
5A5T
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STRUCTURE OF MAMMALIAN EIF3 IN THE CONTEXT OF THE 43S PREINITIATION COMPLEX
Descriptor:EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E, ...
Authors:des-Georges, A., Dhote, V., Kuhn, L., Hellen, C.U.T., Pestova, T.V., Frank, J., Hashem, Y.
Deposit date:2015-06-21
Release date:2015-09-09
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
5A5U
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STRUCTURE OF MAMMALIAN EIF3 IN THE CONTEXT OF THE 43S PREINITIATION COMPLEX
Descriptor:EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I
Authors:des-Georges, A., Dhote, V., Kuhn, L., Hellen, C.U.T., Pestova, T.V., Frank, J., Hashem, Y.
Deposit date:2015-06-21
Release date:2015-09-09
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
3E1Y
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CRYSTAL STRUCTURE OF HUMAN ERF1/ERF3 COMPLEX
Descriptor:Eukaryotic peptide chain release factor subunit 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ADENOSINE-5'-TRIPHOSPHATE
Authors:Cheng, Z., Lim, M., Kong, C., Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
3E20
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CRYSTAL STRUCTURE OF S.POMBE ERF1/ERF3 COMPLEX
Descriptor:Eukaryotic peptide chain release factor GTP-binding subunit, Eukaryotic peptide chain release factor subunit 1
Authors:Cheng, Z., Lim, M., Kong, C., Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
3J8B
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MODEL OF THE HUMAN EIF3 PCI-MPN OCTAMER DOCKED INTO THE 43S-HCV IRES EM MAP
Descriptor:Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit E, ...
Authors:Erzberger, J.P., Ban, N.
Deposit date:2014-10-08
Release date:2014-10-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex.
Cell(Cambridge,Mass.), 158, 2014
3J8C
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MODEL OF THE HUMAN EIF3 PCI-MPN OCTAMER DOCKED INTO THE 43S EM MAP
Descriptor:Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit E, ...
Authors:Erzberger, J.P., Ban, N.
Deposit date:2014-10-08
Release date:2014-10-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11.6 Å)
Cite:Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex.
Cell(Cambridge,Mass.), 158, 2014