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1D7Q
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BU of 1d7q by Molmil
HUMAN TRANSLATION INITIATION FACTOR EIF1A
Descriptor: PROTEIN (N-TERMINAL HISTIDINE TAG), TRANSLATION INITIATION FACTOR 1A
Authors:Battiste, J.L, Pestova, T.V, Hellen, C.U.T, Wagner, G.
Deposit date:1999-10-19
Release date:2000-03-17
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The eIF1A solution structure reveals a large RNA-binding surface important for scanning function.
Mol.Cell, 5, 2000
1HU3
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BU of 1hu3 by Molmil
MIDDLE DOMAIN OF HUMAN EIF4GII
Descriptor: EIF4GII
Authors:Marcotrigiano, J, Lomakin, I, Pestova, T.V, Hellen, C.U.T, Sonenberg, N, Burley, S.K.
Deposit date:2001-01-03
Release date:2001-02-21
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.
Mol.Cell, 7, 2001
2IF1
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BU of 2if1 by Molmil
HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES
Descriptor: EIF1
Authors:Fletcher, C.M, Hellen, C.U.T, Pestova, T.V, Wagner, G.
Deposit date:1998-08-04
Release date:1999-05-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure and interactions of the translation initiation factor eIF1.
EMBO J., 18, 1999
7A01
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BU of 7a01 by Molmil
The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ...
Authors:Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-08-05
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
5A5U
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BU of 5a5u by Molmil
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
Descriptor: EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I
Authors:des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y.
Deposit date:2015-06-21
Release date:2015-09-09
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
5A5T
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BU of 5a5t by Molmil
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E, ...
Authors:des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y.
Deposit date:2015-06-21
Release date:2015-09-09
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
3J5Y
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BU of 3j5y by Molmil
Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
Descriptor: 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ...
Authors:des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2013-11-21
Release date:2013-12-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
4C4Q
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BU of 4c4q by Molmil
Cryo-EM map of the CSFV IRES in complex with the small ribosomal 40S subunit and DHX29
Descriptor: INTERNAL RIBOSOMAL ENTRY SITE
Authors:Hashem, Y, desGeorges, A, Dhote, V, Langlois, R, Liao, H.Y, Grassucci, R.A, Pestova, T.V, Hellen, C.U.T, Frank, J.
Deposit date:2013-09-07
Release date:2013-10-30
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Hepatitis-C-Virus-Like Internal Ribosome Entry Sites Displace Eif3 to Gain Access to the 40S Subunit
Nature, 503, 2013
4D61
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BU of 4d61 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D67
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BU of 4d67 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 28S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-10
Release date:2015-03-04
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
4D5N
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BU of 4d5n by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: CRICKET PARALYSIS VIRUS IRES RNA, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-06
Release date:2015-02-04
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5L
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BU of 4d5l by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-05
Release date:2015-02-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5Y
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BU of 4d5y by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
7SYP
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BU of 7syp by Molmil
Structure of the wt IRES and 40S ribosome binary complex, open conformation. Structure 10(wt)
Descriptor: 18S rRNA, HCV IRES, HCV IRES partially loaded mRNA portion, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYQ
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BU of 7syq by Molmil
Structure of the wt IRES and 40S ribosome ternary complex, open conformation. Structure 11(wt)
Descriptor: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYV
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BU of 7syv by Molmil
Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)
Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-20
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYO
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BU of 7syo by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYS
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BU of 7sys by Molmil
Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII).
Descriptor: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYR
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BU of 7syr by Molmil
Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt).
Descriptor: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-27
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYL
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BU of 7syl by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYH
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BU of 7syh by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 2(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYX
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BU of 7syx by Molmil
Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYU
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BU of 7syu by Molmil
Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYI
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BU of 7syi by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYJ
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BU of 7syj by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII)
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
Authors:Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2021-11-25
Release date:2022-07-13
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022

 

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