Author results

1MW8
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN H365R MUTANT OF 67 KDA N-TERMINAL FRAGMENT OF E. COLI DNA TOPOISOMERASE I AND 5'-ACTTCGGGATG-3'
Descriptor:5'-D(*AP*CP*TP*TP*CP*GP*GP*GP*AP*TP*G)-3', DNA Topoisomerase I, SULFATE ION, ...
Authors:Perry, K., Mondragon, A.
Deposit date:2002-09-27
Release date:2003-10-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Complex between E. coli DNA Topoisomerase I and Single-Stranded DNA.
Structure, 11, 2003
1MW9
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CRYSTAL STRUCTURE OF H365R MUTANT OF 67 KDA N-TERMINAL FRAGMENT OF E. COLI DNA TOPOISOMERASE I
Descriptor:DNA Topoisomerase I, SULFATE ION
Authors:Perry, K., Mondragon, A.
Deposit date:2002-09-27
Release date:2003-10-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structure of a Complex between E. coli DNA Topoisomerase I and Single-Stranded DNA.
Structure, 11, 2003
2H7F
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STRUCTURE OF VARIOLA TOPOISOMERASE COVALENTLY BOUND TO DNA
Descriptor:5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', DNA topoisomerase 1
Authors:Perry, K., Hwang, Y., Bushman, F.D., Van Duyne, G.D.
Deposit date:2006-06-02
Release date:2006-08-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
2H7G
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STRUCTURE OF VARIOLA TOPOISOMERASE NON-COVALENTLY BOUND TO DNA
Descriptor:5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', DNA topoisomerase 1
Authors:Perry, K., Hwang, Y., Bushman, F.D., Van Duyne, G.D.
Deposit date:2006-06-02
Release date:2006-08-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
3IGC
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SMALLPOX VIRUS TOPOISOMERASE-DNA TRANSITION STATE
Descriptor:DNA topoisomerase 1, 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', 5'-D(*AP*TP*TP*CP*C)-3', ...
Authors:Perry, K., Hwang, Y., Bushman, F.D., Van Duyne, G.D.
Deposit date:2009-07-27
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic.
Structure, 18, 2010
5JLV
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH HUMAN GLYCOSYLATED SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C, ACETATE ION, ...
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JMC
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH RAT SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
3V64
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CRYSTAL STRUCTURE OF AGRIN AND LRP4
Descriptor:Low-density lipoprotein receptor-related protein 4, agrin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zong, Y., Zhang, B., Gu, S., Lee, K., Zhou, J., Yao, G., Figueiedo, D., Perry, K., Mei, L., Jin, R.
Deposit date:2011-12-18
Release date:2012-04-25
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of agrin-LRP4-MuSK signaling.
Genes Dev., 26, 2012
4KIS
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CRYSTAL STRUCTURE OF A LSR-DNA COMPLEX
Descriptor:Putative integrase [Bacteriophage A118], DNA (26-MER), ZINC ION, ...
Authors:Rutherford, K., Yuan, P., Perry, K., Van Duyne, G.D.
Deposit date:2013-05-02
Release date:2013-07-10
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Attachment site recognition and regulation of directionality by the serine integrases.
Nucleic Acids Res., 41, 2013
4LO0
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APO HA17-HA33
Descriptor:HA-33, HA-17
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.055 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO1
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HA17-HA33-GAL
Descriptor:HA-33, HA-17, BETA-D-GALACTOSE
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO2
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HA17-HA33-LAC
Descriptor:HA-33, HA-17, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO3
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HA17-HA33-LACNAC
Descriptor:HA-33, HA-17, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO4
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APO HA-70
Descriptor:HA-70, CHLORIDE ION
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.871 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO5
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HA70-ALPHA2,3-SIALC
Descriptor:HA-70, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO6
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HA70-ALPHA2,6-SIALC
Descriptor:HA-70, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO7
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HA70(D3)-HA17-HA33
Descriptor:HA-70, HA-33, HA-17
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.73 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO8
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HA70(D3)-HA17
Descriptor:HA-70, HA-17
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4OUJ
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CRYSTAL STRUCTURE OF HA33B-LAC
Descriptor:Hemagglutinin component HA33, ALPHA-LACTOSE
Authors:Lee, K., Lam, K.-H., Perry, K., Rummel, A., Jin, R.
Deposit date:2014-02-17
Release date:2014-06-04
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex.
Biochem.Biophys.Res.Commun., 446, 2014
4QD2
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MOLECULAR BASIS FOR DISRUPTION OF E-CADHERIN ADHESION BY BOTULINUM NEUROTOXIN A COMPLEX
Descriptor:Hemagglutinin component HA33, Hemagglutinin component HA17, Hemagglutinin component HA70, ...
Authors:Lee, K., Zhong, X., Gu, S., Kruel, A., Dorner, M.B., Perry, K., Rummel, A., Dong, M., Jin, R.
Deposit date:2014-05-13
Release date:2014-06-25
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex.
Science, 344, 2014
4GLI
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CRYSTAL STRUCTURE OF HUMAN SMN YG-DIMER
Descriptor:Maltose-binding periplasmic protein, Survival motor neuron protein chimera
Authors:Martin, R.S., Perry, K., Van Duyne, G.D.
Deposit date:2012-08-14
Release date:2012-10-17
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:The survival motor neuron protein forms soluble glycine zipper oligomers.
Structure, 20, 2012
3IX1
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PERIPLASMIC N-FORMYL-4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE BINDING PROTEIN FROM BACILLUS HALODURANS
Descriptor:N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein, N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamide
Authors:Bale, S., Rajashankar, K.R., Perry, K., Begley, T.P., Ealick, S.E.
Deposit date:2009-09-03
Release date:2010-10-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:HMP Binding Protein ThiY and HMP-P Synthase THI5 Are Structural Homologues.
Biochemistry, 49, 2010
3V0A
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2.7 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA
Descriptor:BoNT/A, NTNH, Llama antibody F12, ...
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0B
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3.9 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA
Descriptor:BoNT/A, NTNH, ZINC ION, ...
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0C
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4.3 ANGSTROM CRYSTAL STRUCTURE OF AN INACTIVE BONT/A (E224Q/R363A/Y366F)
Descriptor:BoNT/A, ZINC ION
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
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