4FVM
 
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4FXD
 | | Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA | | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*CP*GP*CP*TP*GP*CP*CP*CP*GP*CP*CP*T)-3'), DNA polymerase alpha catalytic subunit A, RNA (5'-R(*AP*GP*GP*CP*GP*GP*GP*CP*AP*G)-3') | | Authors: | Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. | | Deposit date: | 2012-07-03 | | Release date: | 2013-02-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
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4B08
 | | Yeast DNA polymerase alpha, Selenomethionine protein | | Descriptor: | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A | | Authors: | Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. | | Deposit date: | 2012-06-29 | | Release date: | 2013-02-27 | | Last modified: | 2013-05-01 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha
Elife, 2, 2013
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4FYD
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2XKJ
 | | CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE) | | Descriptor: | GLYCEROL, SULFATE ION, TOPOISOMERASE IV | | Authors: | Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D. | | Deposit date: | 2010-07-08 | | Release date: | 2010-09-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
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2XKK
 | | CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE) | | Descriptor: | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA, MAGNESIUM ION, ... | | Authors: | Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D. | | Deposit date: | 2010-07-08 | | Release date: | 2010-09-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
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4BPW
 | | Crystal structure of human primase bound to UTP | | Descriptor: | DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ... | | Authors: | Kilkenny, M.L, Perera, R.L, Pellegrini, L. | | Deposit date: | 2013-05-28 | | Release date: | 2013-09-25 | | Last modified: | 2013-10-16 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
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4BPU
 | | Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain. | | Descriptor: | DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, GLYCEROL, ... | | Authors: | Kilkenny, M.L, Perera, R.L, Pellegrini, L. | | Deposit date: | 2013-05-28 | | Release date: | 2013-09-25 | | Last modified: | 2013-10-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
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4BPX
 | | Crystal structure of human primase in complex with the primase- binding motif of DNA polymerase alpha | | Descriptor: | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT, DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, ... | | Authors: | Kilkenny, M.L, Perera, R.L, Pellegrini, L. | | Deposit date: | 2013-05-28 | | Release date: | 2013-09-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
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3LGB
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6I52
 | | Yeast RPA bound to ssDNA | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ... | | Authors: | Yates, L.A, Aramayo, R.J, Zhang, X. | | Deposit date: | 2018-11-12 | | Release date: | 2018-12-19 | | Last modified: | 2019-01-02 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
Nat Commun, 9, 2018
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5NXQ
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4C8H
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4C95
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4C93
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4C8S
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5HOI
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5HOG
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