Author results

4ABX
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CRYSTAL STRUCTURE OF DEINOCOCCUS RADIODURANS RECN COILED-COIL DOMAIN
Descriptor:DNA REPAIR PROTEIN RECN
Authors:Pellegrino, S., Radzimanowski, J., de Sanctis, D., McSweeney, S., Timmins, J.
Deposit date:2011-12-12
Release date:2012-12-12
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair.
Structure, 20, 2012
4ABY
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CRYSTAL STRUCTURE OF DEINOCOCCUS RADIODURANS RECN HEAD DOMAIN
Descriptor:DNA REPAIR PROTEIN RECN
Authors:Pellegrino, S., Radzimanowski, J., de Sanctis, D., McSweeney, S., Timmins, J.
Deposit date:2011-12-12
Release date:2012-12-12
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair.
Structure, 20, 2012
4AD8
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CRYSTAL STRUCTURE OF A DELETION MUTANT OF DEINOCOCCUS RADIODURANS RECN
Descriptor:DNA REPAIR PROTEIN RECN
Authors:Pellegrino, S., Radzimanowski, J., de Sanctis, D., McSweeney, S., Timmins, J.
Deposit date:2011-12-22
Release date:2012-12-12
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (3.998 Å)
Cite:Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair.
Structure, 20, 2012
6GQ1
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CRYO-EM RECONSTRUCTION OF YEAST 80S RIBOSOME IN COMPLEX WITH MRNA, TRNA AND EEF2 (GMPPCP/SORDARIN)
Descriptor:Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 5.8S ribosomal RNA, ...
Authors:Pellegrino, S., Demeshkina, N., Mancera-Martinez, E., Melnikov, S., Simonetti, A., Myasnikov, A., Yusupov, M., Yusupova, G., Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6GQB
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CRYO-EM RECONSTRUCTION OF YEAST 80S RIBOSOME IN COMPLEX WITH MRNA, TRNA AND EEF2 (GDP+ALF4/SORDARIN)
Descriptor:Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 5S ribosomal RNA, ...
Authors:Pellegrino, S., Yusupov, M., Yusupova, G., Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6GQV
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CRYO-EM RECOSNTRUCTION OF YEAST 80S RIBOSOME IN COMPLEX WITH MRNA, TRNA AND EEF2 (GMPPCP)
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Pellegrino, S., Yusupov, M., Yusupova, G., Hashem, Y.
Deposit date:2018-06-08
Release date:2018-07-11
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
5ON6
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CRYSTAL STRUCTURE OF HAEMANTHAMINE BOUND TO THE 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Pellegrino, S., Meyer, M., Yusupova, G., Yusupov, M.
Deposit date:2017-08-03
Release date:2018-02-28
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3.100002 Å)
Cite:The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth.
Structure, 26, 2018
6HHQ
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CRYSTAL STRUCTURE OF COMPOUND C45 BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Pellegrino, S., Vanderwal, C.D., Yusupov, M.
Deposit date:2018-08-28
Release date:2019-02-20
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 2019
5MEI
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CRYSTAL STRUCTURE OF AGELASTATIN A BOUND TO THE 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, J.C.P., Lu, J., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R., Liu, J.O.
Deposit date:2016-11-15
Release date:2017-06-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
5TBW
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CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
4L29
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STRUCTURE OF WTMHC CLASS I WITH NY-ESO1 DOUBLE MUTANT
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Halabelian, L., Giorgetti, S., Bellotti, V., Bolognesi, M., Ricagno, S.
Deposit date:2013-06-04
Release date:2013-12-25
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4L3C
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STRUCTURE OF HLA-A2 IN COMPLEX WITH D76N B2M MUTANT AND NY-ESO1 DOUBLE MUTANT
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Halabelian, L., Giorgetti, S., Bellotti, V., Bolognesi, M., Ricagno, S.
Deposit date:2013-06-05
Release date:2013-12-25
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4OJ3
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THE CRYSTAL STRUCTURE OF V84P MUTANT OF S. SOLFATARICUS ACYLPHOSPHATASE
Descriptor:Acylphosphatase, SULFATE ION, GLYCEROL
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-01-20
Release date:2014-06-04
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase.
Febs J., 281, 2014
4OJG
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THE CRYSTAL STRUCTURE OF V84D MUTANT OF S. SOLFATARICUS ACYLPHOSPHATASE
Descriptor:Acylphosphatase, PHOSPHATE ION, GLYCEROL
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-01-21
Release date:2014-06-04
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.377 Å)
Cite:Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase.
Febs J., 281, 2014
4OJH
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THE CRYSTAL STRUCTURE OF TRUNCATED, Y86E MUTANT OF S. SOLFATARICUS ACYLPHOSPHATASE
Descriptor:Acylphosphatase, SULFATE ION
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-01-21
Release date:2014-06-04
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Edge strand engineering prevents native-like aggregation in Sulfolobus solfataricus acylphosphatase.
Febs J., 281, 2014
6GB5
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STRUCTURE OF H-2DB WITH TRUNCATED SEV PEPTIDE AND GL
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Sandalova, T., Achour, A.
Deposit date:2018-04-13
Release date:2019-03-06
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc. Natl. Acad. Sci. U.S.A., 2019
6GB6
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STRUCTURE OF H-2KB WITH DIPEPTIDE GL
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Sandalova, T., Achour, A.
Deposit date:2018-04-13
Release date:2019-03-06
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc. Natl. Acad. Sci. U.S.A., 2019
6GB7
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STRUCTURE OF H-2DB WITH SCOOP LOOP FROM TAPASIN
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Sandalova, T., Achour, A.
Deposit date:2018-04-13
Release date:2019-03-06
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc. Natl. Acad. Sci. U.S.A., 2019
5JWD
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CRYSTAL STRUCTURE OF H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP392-401 PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Buratto, J., Badia-Martinez, D., Norstrom, M., Sandalova, T., Achour, A.
Deposit date:2016-05-12
Release date:2017-05-24
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
PLoS ONE, 12, 2017
5JWE
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CRYSTAL STRUCTURE OF H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP92-101 PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Buratto, J., Badia-Martinez, D., Norstrom, M., Sandalova, T., Achour, A.
Deposit date:2016-05-12
Release date:2017-05-24
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
PLoS ONE, 12, 2017
5MZM
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STRUCTURE OF H-2DB IN COMPLEX WITH TEIPP APL TRH4 P3P
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Hafstrand, I., Achour, A., Sandalova, T.
Deposit date:2017-02-01
Release date:2018-03-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.
J. Immunol., 200, 2018
5NI9
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CRYSTAL STRUCTURE OF HLA-DRB1*04:01 WITH THE ALPHA-ENOLASE PEPTIDE 326-340
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Gerstner, C., Dubnovitsky, A.
Deposit date:2017-03-23
Release date:2018-06-13
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint.
J. Autoimmun., 92, 2018
5NIG
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CRYSTAL STRUCTURE OF HLA-DRB1*04:01 WITH MODIFIED ALPHA-ENOLASE PEPTIDE 326-340 (ARGININE 327 TO CITRULLINE)
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Gerstner, C., Dubnovitsky, A.
Deposit date:2017-03-24
Release date:2018-06-13
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint.
J. Autoimmun., 92, 2018