Author results

1AY9
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WILD-TYPE UMUD' FROM E. COLI
Descriptor:UMUD PROTEIN
Authors:Peat, T.S., Frank, E.G., Mcdonald, J.P., Levine, A.S., Woodgate, R., Hendrickson, W.A.
Deposit date:1997-11-15
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The UmuD' protein filament and its potential role in damage induced mutagenesis.
Structure, 4, 1996
1UMU
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STRUCTURE DETERMINATION OF UMUD' BY MAD PHASING OF THE SELENOMETHIONYL PROTEIN
Descriptor:UMUD'
Authors:Peat, T.S., Hendrickson, W.A.
Deposit date:1996-03-07
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the UmuD' protein and its regulation in response to DNA damage.
Nature, 380, 1996
3ZSQ
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-06-30
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSR
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, CHLORIDE ION, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-06-30
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSV
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSW
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, THREONINE, SULFATE ION, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSX
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSY
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETATE ION, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSZ
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETATE ION, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZT0
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, (4-CARBOXY-1,3-BENZODIOXOL-5-YL)-N-{2-[(4-METHOXYBENZYL)CARBAMOYL]BENZYL}-N-METHYLMETHANAMINIUM
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZT1
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZT2
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETATE ION, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZT3
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-11
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZT4
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C., Deadman, J.J.
Deposit date:2011-07-01
Release date:2012-07-18
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design
Plos One, 7, 2012
1BKB
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INITIATION FACTOR 5A FROM ARCHEBACTERIUM PYROBACULUM AEROPHILUM
Descriptor:TRANSLATION INITIATION FACTOR 5A
Authors:Peat, T.S., Newman, J., Waldo, G.S., Berendzen, J., Terwilliger, T.C.
Deposit date:1998-07-05
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 A resolution.
Structure, 6, 1998
1QP8
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CRYSTAL STRUCTURE OF A PUTATIVE FORMATE DEHYDROGENASE FROM PYROBACULUM AEROPHILUM
Descriptor:FORMATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Peat, T.S., Newman, J., Waldo, G.S., Terwilliger, T.C.
Deposit date:1999-06-01
Release date:1999-06-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of a Putative Formate Dehydrogenase from Pyrobaculum Aerophilum
To be Published
3ZCM
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN.
Descriptor:HIV INTEGRASE, SULFATE ION, GLYCEROL, ...
Authors:Peat, T.S.
Deposit date:2012-11-21
Release date:2012-12-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
3ZSO
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SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN
Descriptor:INTEGRASE, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S., Newman, J., Rhodes, D.I., Deadman, J.J., Vandergraaff, N., Le, G., Jones, E.D., Smith, J.A., Coates, J.A.V., Thienthong, N., Dolezal, O., Ryan, J.H., Savage, G.P., Francis, C.L.
Deposit date:2011-06-30
Release date:2012-07-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design.
Plos One, 7, 2012
4B2G
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CRYSTAL STRUCTURE OF AN INDOLE-3-ACETIC ACID AMIDO SYNTHASE FROM VITIS VINIFERA INVOLVED IN AUXIN HOMEOSTASIS
Descriptor:GH3-1 AUXIN CONJUGATING ENZYME, MALONATE ION, [(2S,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl] 2-(1H-indol-3-yl)ethyl hydrogen phosphate
Authors:Peat, T.S., Bottcher, C., Newman, J., Lucent, D., Cowieson, N., Davies, C.
Deposit date:2012-07-16
Release date:2012-12-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of an Indole-3-Acetic Acid Amido Synthetase from Grapevine Involved in Auxin Homeostasis.
Plant Cell, 24, 2012
4BVQ
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CYANURIC ACID HYDROLASE: EVOLUTIONARY INNOVATION BY STRUCTURAL CONCATENATION.
Descriptor:CYANURIC ACID AMIDOHYDROLASE, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Peat, T.S., Balotra, S., Wilding, M., French, N.G., Briggs, L.J., Panjikar, S., Cowieson, N., Newman, J., Scott, C.
Deposit date:2013-06-28
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cyanuric Acid Hydrolase: Evolutionary Innovation by Structural Concatenation.
Mol.Microbiol., 88, 2013
4BVR
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CYANURIC ACID HYDROLASE: EVOLUTIONARY INNOVATION BY STRUCTURAL CONCATENATION.
Descriptor:CYANURIC ACID AMIDOHYDROLASE, MAGNESIUM ION, 1,3,5-triazine-2,4,6-triol, ...
Authors:Peat, T.S., Balotra, S., Wilding, M., French, N.G., Briggs, L.J., Panjikar, S., Cowieson, N., Newman, J., Scott, C.
Deposit date:2013-06-28
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Cyanuric Acid Hydrolase: Evolutionary Innovation by Structural Concatenation.
Mol.Microbiol., 88, 2013
4BVS
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CYANURIC ACID HYDROLASE: EVOLUTIONARY INNOVATION BY STRUCTURAL CONCATENATION.
Descriptor:CYANURIC ACID AMIDOHYDROLASE, MAGNESIUM ION, 1,3,5-triazine-2,4,6-triamine
Authors:Peat, T.S., Balotra, S., Wilding, M., French, N.G., Briggs, L.J., Panjikar, S., Cowieson, N., Newman, J., Scott, C.
Deposit date:2013-06-28
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cyanuric Acid Hydrolase: Evolutionary Innovation by Structural Concatenation.
Mol.Microbiol., 88, 2013
4BVT
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CYANURIC ACID HYDROLASE: EVOLUTIONARY INNOVATION BY STRUCTURAL CONCATENATION
Descriptor:CYANURIC ACID AMIDOHYDROLASE, MAGNESIUM ION, BARBITURIC ACID, ...
Authors:Peat, T.S., Balotra, S., Wilding, M., French, N.G., Briggs, L.J., Panjikar, S., Cowieson, N., Newman, J., Scott, C.
Deposit date:2013-06-28
Release date:2013-07-17
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cyanuric Acid Hydrolase: Evolutionary Innovation by Structural Concatenation.
Mol.Microbiol., 88, 2013
4CCF
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STRUCTURE OF RESPIRATORY SYNCYTIAL VIRUS F PROTEIN HEAD DOMAIN
Descriptor:FUSION GLYCOPROTEIN F0, SULFATE ION
Authors:Peat, T.S.
Deposit date:2013-10-22
Release date:2013-11-13
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of Respiratory Syncytial Virus F Protein Head Domain
To be Published
4CE9
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INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE
Descriptor:INTEGRASE, SULFATE ION, ACETIC ACID, ...
Authors:Peat, T.S.
Deposit date:2013-11-11
Release date:2013-11-20
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interrogating HIV Integrase for Compounds that Bind- a Sampl Challenge.
J.Comput.Aided Mol.Des., 28, 2014