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5JUM
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DCTP OPPOSITE N-(2'-DEOXYGUANOSIN-8- YL)-3-AMINOBENZANTHRONE (C8-DG-ABA)
Descriptor:DNA polymerase eta, DNA (5'-D(*C*AP*TP*(4E9)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Politica, D.A., Stone, M.P., Egli, M.
Deposit date:2016-05-10
Release date:2016-09-07
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase eta.
Chembiochem, 17, 2016
2KK5
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HIGH FIDELITY BASE PAIRING AT THE 3'-TERMINUS
Descriptor:5'-D(*AP*CP*GP*CP*GP*(2AU))-3', 9,10-dioxo-9,10-dihydroanthracene-2-carboxamide
Authors:Patra, A., Richert, C.
Deposit date:2009-06-15
Release date:2009-07-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High fidelity base pairing at the 3'-terminus.
J.Am.Chem.Soc., 131, 2009
4HTU
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STRUCTURE OF 5-CHLOROURACIL MODIFIED A:U BASE PAIR
Descriptor:Ribonuclease H, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*(UCL)P*CP*GP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Patra, A., Egli, M.
Deposit date:2012-11-01
Release date:2012-12-19
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.489 Å)
Cite:Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Nucleic Acids Res., 41, 2013
4HUE
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STRUCTURE OF 5-CHLOROURACIL MODIFIED G:U BASE PAIR
Descriptor:Ribonuclease H, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(UCL)P*GP*CP*G)-3'), GLYCEROL, ...
Authors:Patra, A., Egli, M.
Deposit date:2012-11-02
Release date:2012-12-19
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.561 Å)
Cite:Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Nucleic Acids Res., 41, 2013
4HUF
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STRUCTURE OF 5-CHLOROURACIL MODIFIED A:U BASE PAIR
Descriptor:Ribonuclease H, DNA (5'-D(*CP*GP*CP*GP*AP*AP*(UCL)P*TP*CP*GP*CP*G)-3'), GLYCEROL, ...
Authors:Patra, A., Egli, M.
Deposit date:2012-11-02
Release date:2012-12-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Nucleic Acids Res., 41, 2013
4HUG
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STRUCTURE OF 5-CHLOROURACIL MODIFIED A:U BASE PAIRS
Descriptor:Ribonuclease H, DNA (5'-D(*CP*GP*CP*GP*AP*AP*(UCL)P*(UCL)P*CP*GP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Patra, A., Egli, M.
Deposit date:2012-11-02
Release date:2012-12-19
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
Nucleic Acids Res., 41, 2013
4O3N
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA IN TERNARY COMPLEX WITH NATIVE DNA AND INCOMING NUCLEOTIDE (DCP)
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.579 Å)
Cite:Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
4O3O
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DATP OPPOSITE AN 8-OXOG CONTAINING DNA TEMPLATE
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
4O3P
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DCTP OPPOSITE AN 8-OXOG CONTAINING DNA TEMPLATE
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
4O3Q
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DGTP OPPOSITE AN 8-OXOG CONTAINING DNA TEMPLATE
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
4O3R
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA EXTENDING AN 8-OXOG DNA LESION: POST INSERTION OF 8-OXOG-DA PAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
4O3S
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA EXTENDING AN 8-OXOG DNA LESION: POST INSERTION OF 8-OXOG-DC PAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.717 Å)
Cite:Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
4RNM
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DAMPNPP OPPOSITE DNA TEMPLATE CONTAINING AN ABASIC SITE
Descriptor:DNA polymerase eta, DNA Template: CAT(3DR)ATGACGCT, DNA Primar: AGCGTCAT, ...
Authors:Patra, A., Egli, M.
Deposit date:2014-10-24
Release date:2015-02-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.144 Å)
Cite:Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 290, 2015
4RNN
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DGMPNPP OPPOSITE DNA TEMPLATE CONTAINING AN ABASIC SITE
Descriptor:DNA polymerase eta, Nucleic acids Template: CAT(3DR)ATGACGCT, Nucleic acids Primar: AGCGTCAT, ...
Authors:Patra, A., Egli, M.
Deposit date:2014-10-24
Release date:2015-02-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.808 Å)
Cite:Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 290, 2015
4RNO
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CRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA EXTENDING AN ABASIC SITE-DA PAIR BY INSERTING DCTP OPPOSITE TEMPLATE G
Descriptor:DNA polymerase eta, Nucleic acids Template: CATG(3DR)TGACGCT, Nucleic acids Primar: AGCGTCAA, ...
Authors:Patra, A., Egli, M.
Deposit date:2014-10-24
Release date:2015-02-18
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 290, 2015
4RU9
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE A MEFAPY-DG ADDUCTED DNA TEMPLATE
Descriptor:DNA polymerase eta, Nucleic acids Template: CAT(MF7)ATGACGCT, Nucleic acids Primar: AGCGTCAT, ...
Authors:Patra, A., Egli, M.
Deposit date:2014-11-18
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
4RUA
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CRYSTAL STRUCTURE OF Y-FAMILY DNA POLYMERASE DPO4 BYPASSING A MEFAPY-DG ADDUCT
Descriptor:DNA polymerase IV, Nucleic acids Template: TCAT(MF7)GAATCCTTCCCCC, Nucleic acids Primar: GGGGGAAGGATTC, ...
Authors:Patra, A., Banerjee, S., Stone, M.P., Egli, M.
Deposit date:2014-11-18
Release date:2015-08-05
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
4RUC
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CRYSTAL STRUCTURE OF Y-FAMILY DNA POLYMERASE DPO4 EXTENDING FROM A MEFAPY-DG:DC PAIR
Descriptor:DNA polymerase IV, Nucleic acids Template: TCAT(MF7)TAATCCTTCCCCC, Nucleic acids Primar: GGGGGAAGGATTAC, ...
Authors:Patra, A., Banerjee, S., Stone, M.P., Egli, M.
Deposit date:2014-11-18
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
5DG7
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DTTP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-08-27
Release date:2016-06-08
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 291, 2016
5DG8
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-08-27
Release date:2016-06-08
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 291, 2016
5DG9
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DGMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-08-27
Release date:2016-06-08
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 291, 2016
5DGA
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6-ETHENODEOXYADENOSINE : DT PAIR BY INSERTING DTMPNPP OPPOSITE TEMPLATE DA
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*AP*(EDA)P*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-08-27
Release date:2016-06-08
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 291, 2016
5DGB
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6-ETHENODEOXYADENOSINE : DA PAIR BY INSERTING DTMPNPP OPPOSITE TEMPLATE DA
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*AP*(EDA)P*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-08-27
Release date:2016-06-08
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 291, 2016
5F9L
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N2-ETHENODEOXYGUANOSINE LESION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(GNE)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-12-09
Release date:2016-12-21
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:Bypass of the 1, N2-Ethenodeoxyguanosine Lesion by Human DNA Polymerase Eta
To Be Published
5F9N
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CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N2-ETHENODEOXYGUANOSINE LESION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(GNE)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A., Egli, M.
Deposit date:2015-12-09
Release date:2016-12-21
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Bypass of the 1, N2-Ethenodeoxyguanosine Lesion by Human DNA Polymerase Eta
To Be Published
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