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Structure of MK2 Complexed with Compound 76
Descriptor:	(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, MAP kinase-activated protein kinase 2, STAUROSPORINE
Authors:	White, A, Wu, J.P, Wang, J, Abeywardane, A, Andersen, D, Emmanuel, M, Gautschi, E, Goldberg, D.R, Kashem, M.A, Lukas, S, Mao, W, Martin, L, Morwick, T, Moss, N, Pargellis, C, Patel, U.R, Patnaude, L, Peet, G.W, Skow, D, Snow, R.J, Ward, Y, Werneburg, B.
Deposit date:	2007-05-18
Release date:	2007-07-31
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	The discovery of carboline analogs as potent MAPKAP-K2 inhibitors Bioorg.Med.Chem.Lett., 17, 2007

Crystal structure of a N-Phenyl-N'-Naphthylurea analog in complex with p38 MAP kinase
Descriptor:	Mitogen-activated protein kinase 14, N-{5-tert-butyl-2-methoxy-3-[({4-[6-(morpholin-4-ylmethyl)pyridin-3-yl]naphthalen-1-yl}carbamoyl)amino]phenyl}methanesulfonamide
Authors:	Qian, K.C.
Deposit date:	2009-03-05
Release date:	2009-10-20
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009