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8A2Q
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BU of 8a2q by Molmil
Structure of the DNA-bound FANCD2-FANCI complex containing phosphomimetic FANCI
Descriptor: DNA (29-MER), FANCD2, Fanconi anemia complementation group I
Authors:Passmore, L.A, Sijacki, T, Alcon, P.
Deposit date:2022-06-06
Release date:2022-09-07
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination.
Nat.Struct.Mol.Biol., 29, 2022
4V1W
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BU of 4v1w by Molmil
3D structure of horse spleen apoferritin determined by electron cryomicroscopy
Descriptor: FERRITIN LIGHT CHAIN
Authors:Russo, C.J, Passmore, L.A.
Deposit date:2014-10-02
Release date:2014-12-10
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Electron Microscopy. Ultrastable Gold Substrates for Electron Cryomicroscopy.
Science, 346, 2014
7ZGR
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BU of 7zgr by Molmil
Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA
Descriptor: Cleavage factor two protein 2, MPE1 isoform 1, Polyadenylation factor subunit 2, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
7ZGP
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BU of 7zgp by Molmil
Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA
Descriptor: MPE1 isoform 1, Polyadenylation factor subunit 2, Protein CFT1, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
7ZGQ
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BU of 7zgq by Molmil
Polymerase module of yeast CPF in complex with the yPIM of Cft2
Descriptor: Cleavage factor two protein 2, Polyadenylation factor subunit 2, Protein CFT1, ...
Authors:Rodriguez-Molina, J.B, Passmore, L.A.
Deposit date:2022-04-04
Release date:2022-05-25
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Mol.Cell, 82, 2022
6FPX
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BU of 6fpx by Molmil
Structure of S. pombe Mmi1 in complex with 11-mer RNA
Descriptor: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-12
Release date:2018-05-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
8A8F
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BU of 8a8f by Molmil
Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
Descriptor: MANGANESE (II) ION, PHOSPHATE ION, RNA end formation protein 2, ...
Authors:Carminati, M, Manav, C.M, Bellini, D, Passmore, L.A.
Deposit date:2022-06-22
Release date:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2
To Be Published
8BPO
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BU of 8bpo by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S.
Deposit date:2022-11-17
Release date:2023-07-05
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
Mol.Cell, 83, 2023
6I1D
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BU of 6i1d by Molmil
Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae
Descriptor: Endoribonuclease YSH1, GLYCEROL, Protein MPE1, ...
Authors:Hill, C.H, Boreikaite, V, Kumar, A, Casanal, A, Kubik, P, Degliesposti, G, Maslen, S, Mariani, A, von Loeffelholz, O, Girbig, M, Skehel, M, Passmore, L.A.
Deposit date:2018-10-28
Release date:2019-02-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex.
Mol.Cell, 73, 2019
6FPP
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BU of 6fpp by Molmil
Structure of S. pombe Mmi1
Descriptor: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPQ
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BU of 6fpq by Molmil
Structure of S. pombe Mmi1 in complex with 7-mer RNA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
4CYJ
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BU of 4cyj by Molmil
Chaetomium thermophilum Pan2:Pan3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYI
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BU of 4cyi by Molmil
Chaetomium thermophilum Pan3
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYK
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BU of 4cyk by Molmil
Structural basis for binding of Pan3 to Pan2 and its function in mRNA recruitment and deadenylation
Descriptor: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3, ZINC ION
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-05-21
Last modified:2021-06-23
Method:SOLUTION NMR
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation.
Embo J., 33, 2014
6SRS
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BU of 6srs by Molmil
Structure of the Fanconi anaemia core subcomplex
Descriptor: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ...
Authors:Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
Deposit date:2019-09-05
Release date:2019-11-06
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6SRI
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BU of 6sri by Molmil
Structure of the Fanconi anaemia core complex
Descriptor: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ...
Authors:Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
Deposit date:2019-09-05
Release date:2019-11-06
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6TNG
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BU of 6tng by Molmil
Structure of FANCD2 in complex with FANCI
Descriptor: Fanconi anemia complementation group I, Uncharacterized protein
Authors:Alcon, P, Shakeel, S, Passmore, L.A.
Deposit date:2019-12-07
Release date:2020-02-19
Last modified:2020-03-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
6TNF
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BU of 6tnf by Molmil
Structure of monoubiquitinated FANCD2 in complex with FANCI and DNA
Descriptor: DNA (33-MER), FANCD2, Fanconi anemia complementation group I, ...
Authors:Alcon, P, Shakeel, S, Passmore, L.A.
Deposit date:2019-12-07
Release date:2020-02-19
Last modified:2020-03-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
6TNI
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BU of 6tni by Molmil
Structure of FANCD2 homodimer
Descriptor: Uncharacterized protein
Authors:Alcon, P, Shakeel, S, Passmore, L.A.
Deposit date:2019-12-08
Release date:2020-02-19
Last modified:2020-03-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
6R9J
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BU of 6r9j by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with A7 RNA
Descriptor: A7 RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.326 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9P
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BU of 6r9p by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAUUAA RNA
Descriptor: AAUUAA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9O
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BU of 6r9o by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAGGA RNA
Descriptor: AAGGA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.319 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9I
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BU of 6r9i by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module
Descriptor: PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9M
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BU of 6r9m by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAGGAA RNA
Descriptor: AAGGAA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.329 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
6R9Q
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BU of 6r9q by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AACCAA RNA
Descriptor: AACCAA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Authors:Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
Deposit date:2019-04-03
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.079 Å)
Cite:The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019

 

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