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8H53
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BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
Descriptor: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2022-10-12
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
To Be Published
4ZYA
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BU of 4zya by Molmil
The N-terminal extension domain of human asparaginyl-tRNA synthetase
Descriptor: Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ...
Authors:Park, J.S, Park, M.C, Goughnour, P, Kim, H.S, Kim, S.J, Kim, H.J, Kim, S.H, Han, B.W.
Deposit date:2015-05-21
Release date:2016-05-25
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
6K8C
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BU of 6k8c by Molmil
Crystal structure of Helicobacter pylori folylpolyglutamate synthetase
Descriptor: CITRIC ACID, Folylpolyglutamate synthase (FolC), GLYCEROL
Authors:Park, J.S, Han, B.W.
Deposit date:2019-06-11
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.95174968 Å)
Cite:Structural Analyses of Helicobacter Pylori FolC Conducting Glutamation in Folate Metabolism.
Crystals, 2019
7TYD
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BU of 7tyd by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder in P21 space group
Descriptor: Binder, Fibroblast growth factor receptor 4
Authors:Park, J.S, Lee, S.
Deposit date:2022-02-12
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein.
Cell Rep, 41, 2022
5XIX
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BU of 5xix by Molmil
The canonical domain of human asparaginyl-tRNA synthetase
Descriptor: Asparagine--tRNA ligase, cytoplasmic, GLYCEROL
Authors:Park, J.S, Han, B.W.
Deposit date:2017-04-28
Release date:2018-05-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
3TD5
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BU of 3td5 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with L-Ala-gamma-D-Glu-m-DAP-D-Ala-D-Ala
Descriptor: CHLORIDE ION, Outer membrane protein omp38, peptide(L-Ala-gamma-D-Glu-m-DAP-D-Ala-D-Ala)
Authors:Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
Deposit date:2011-08-10
Release date:2011-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
3TD4
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BU of 3td4 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate
Descriptor: 2,6-DIAMINOPIMELIC ACID, Outer membrane protein omp38
Authors:Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
Deposit date:2011-08-10
Release date:2011-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
3TD3
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BU of 3td3 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with glycine
Descriptor: GLYCINE, Outer membrane protein omp38
Authors:Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
Deposit date:2011-08-10
Release date:2011-10-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
6A0H
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BU of 6a0h by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant with Asn-Leu-Ala-Ala-Arg peptide
Descriptor: 5-mer peptide ASN-LEU-ALA-ALA-ARG, GLYCEROL, PHOSPHATE ION, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2018-06-05
Release date:2019-12-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.185 Å)
Cite:Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
6A0F
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BU of 6a0f by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant with Asn-Phe-Ala-Ala-Arg peptide
Descriptor: 5-mer peptide Asn-Phe-Ala-Ala-Arg, GLYCEROL, PHOSPHATE ION, ...
Authors:Park, J.S, Han, B.W.
Deposit date:2018-06-05
Release date:2019-12-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.384 Å)
Cite:Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
6A0I
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BU of 6a0i by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant
Descriptor: GLYCEROL, PHOSPHATE ION, Protein N-terminal asparagine amidohydrolase
Authors:Park, J.S, Han, B.W.
Deposit date:2018-06-05
Release date:2019-12-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
6A0E
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BU of 6a0e by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1)
Descriptor: GLYCEROL, PHOSPHATE ION, Protein N-terminal asparagine amidohydrolase
Authors:Park, J.S, Han, B.W.
Deposit date:2018-06-05
Release date:2019-12-11
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (1.947 Å)
Cite:Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
7N1J
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BU of 7n1j by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
Descriptor: Binder, Fibroblast growth factor receptor 4
Authors:Park, J.S, Lee, S.
Deposit date:2021-05-27
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1K
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BU of 7n1k by Molmil
Crystal structure of a de novo-designed mini-protein targeting FGFR
Descriptor: Binder
Authors:Park, J.S, Lee, S.
Deposit date:2021-05-27
Release date:2022-04-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
5I2Q
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BU of 5i2q by Molmil
Structure of EF-hand containing protein
Descriptor: CALCIUM ION, EF-hand domain-containing protein D2
Authors:Park, K.R, Kwon, M.S, An, J.Y, Lee, J.G, Youn, H.S, Lee, Y, Kang, J.Y, Kim, T.G, Lim, J.J, Park, J.S, Lee, S.H, Song, W.K, Cheong, H, Jun, C, Eom, S.H.
Deposit date:2016-02-09
Release date:2016-12-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.935 Å)
Cite:Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1.
Sci Rep, 6, 2016
5I2O
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BU of 5i2o by Molmil
Structure of EF-hand containing protein
Descriptor: CALCIUM ION, EF-hand domain-containing protein D2
Authors:Park, K.R, Kwon, M.S, An, J.Y, Lee, J.G, Youn, H.S, Lee, Y, Kang, J.Y, Kim, T.G, Lim, J.J, Park, J.S, Lee, S.H, Song, W.K, Cheong, H, Jun, C, Eom, S.H.
Deposit date:2016-02-09
Release date:2016-12-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1.
Sci Rep, 6, 2016
5I2L
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BU of 5i2l by Molmil
Structure of EF-hand containing protein
Descriptor: CALCIUM ION, EF-hand domain-containing protein D2
Authors:Park, K.R, Kwon, M.S, An, J.Y, Lee, J.G, Youn, H.S, Lee, Y, Kang, J.Y, Kim, T.G, Lim, J.J, Park, J.S, Lee, S.H, Song, W.K, Cheong, H, Jun, C, Eom, S.H.
Deposit date:2016-02-09
Release date:2016-12-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1.
Sci Rep, 6, 2016
6VGI
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BU of 6vgi by Molmil
Crystal Structures of FLAP bound to MK-866
Descriptor: 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid, 5-lipoxygenase-activating protein, SULFATE ION
Authors:Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H.
Deposit date:2020-01-08
Release date:2020-12-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Biochim Biophys Acta Gen Subj, 1865, 2020
6VGC
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BU of 6vgc by Molmil
Crystal Structures of FLAP bound to DG-031
Descriptor: (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, 5-lipoxygenase-activating protein, CALCIUM ION, ...
Authors:Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H.
Deposit date:2020-01-07
Release date:2020-12-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Biochim Biophys Acta Gen Subj, 1865, 2020
6VL4
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BU of 6vl4 by Molmil
Crystal Structure of mPGES-1 bound to DG-031
Descriptor: (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, Prostaglandin E synthase, TETRAETHYLENE GLYCOL, ...
Authors:Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H.
Deposit date:2020-01-22
Release date:2020-12-02
Last modified:2020-12-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Biochim Biophys Acta Gen Subj, 1865, 2020
5Y7D
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BU of 5y7d by Molmil
Crystal structure of human Endothelial-overexpressed LPS associated factor 1
Descriptor: CHLORIDE ION, GLYCEROL, Protein CXorf40A, ...
Authors:Park, S.H, Kim, M.J, Park, J.S, Kim, H.J, Han, B.W.
Deposit date:2017-08-17
Release date:2018-08-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal Structure of Human EOLA1 Implies Its Possibility of RNA Binding.
Molecules, 24, 2019
7E5Z
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BU of 7e5z by Molmil
Dehydrogenase holoenzyme
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Roh, S.H, Park, J.S, Heo, Y.Y.
Deposit date:2021-02-21
Release date:2022-02-23
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Dehydrogenase holoenzyme
To Be Published
4G4W
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BU of 4g4w by Molmil
Crystal structure of peptidoglycan-associated lipoprotein from Acinetobacter baumannii
Descriptor: ALANINE, GLYCEROL, Peptidoglycan-associated lipoprotein, ...
Authors:Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
Deposit date:2012-07-16
Release date:2013-07-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
to be published
4G4V
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BU of 4g4v by Molmil
Crystal structure of peptidoglycan-associated lipoprotein from Acinetobacter baumannii
Descriptor: 2,6-DIAMINOPIMELIC ACID, Peptidoglycan-associated lipoprotein
Authors:Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
Deposit date:2012-07-16
Release date:2013-07-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
To be Published
4G4Y
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BU of 4g4y by Molmil
Crystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumannii
Descriptor: ALANINE, Outer membrane protein Omp38, SULFATE ION
Authors:Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
Deposit date:2012-07-16
Release date:2013-07-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
To be Published

 

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