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7ZRA
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BU of 7zra by Molmil
Crystal structure of E.coli LexA in complex with nanobody NbSOS1(Nb14497)
Descriptor: 1,2-ETHANEDIOL, LexA repressor, Nanobody NbSOS1 (Nb14497)
Authors:Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L.
Deposit date:2022-05-04
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Structure, 30, 2022
4W6Y
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BU of 4w6y by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF9
Descriptor: F18 fimbrial adhesin AC, Nanobody NbFedF9, SULFATE ION
Authors:Moonens, K, De Kerpel, M, Coddens, A, Cox, E, Pardon, E, Remaut, H, De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6W
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BU of 4w6w by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF6
Descriptor: F18 fimbrial adhesin AC, NbFedF6
Authors:Moonens, K, De Kerpel, M, Annelies, C, Cox, E, Pardon, E, Remaut, H, De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6X
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BU of 4w6x by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF7
Descriptor: F18 fimbrial adhesin AC, Nanobody NbFedF7
Authors:Moonens, K, De Kerpel, M, Coddens, A, Cox, E, Pardon, E, Remaut, H, De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
7ZC2
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BU of 7zc2 by Molmil
Dipeptide and tripeptide Permease C (DtpC)
Descriptor: Amino acid/peptide transporter
Authors:Killer, M, Finocchio, G, Pardon, E, Steyaert, J, Loew, C.
Deposit date:2022-03-25
Release date:2022-07-06
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C.
Front Mol Biosci, 9, 2022
4WEN
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BU of 4wen by Molmil
Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V2
Descriptor: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC
Authors:Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEM
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BU of 4wem by Molmil
Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V1
Descriptor: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC, PHOSPHATE ION
Authors:Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEU
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BU of 4weu by Molmil
Co-complex structure of the F4 fimbrial adhesin FaeG variant ad with llama single domain antibody V3
Descriptor: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD
Authors:Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H.
Deposit date:2014-09-11
Release date:2015-02-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
6MXT
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BU of 6mxt by Molmil
Crystal structure of human beta2 adrenergic receptor bound to salmeterol and Nb71
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Endolysin, ...
Authors:Masureel, M, Zou, Y, Picard, L.P, van der Westhuizen, E, Mahoney, J.P, Rodrigues, J.P.G.L.M, Mildorf, T.J, Dror, R.O, Shaw, D.E, Bouvier, M, Pardon, E, Steyaert, J, Sunahara, R.K, Weis, W.I, Zhang, C, Kobilka, B.K.
Deposit date:2018-10-31
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95934224 Å)
Cite:Structural insights into binding specificity, efficacy and bias of a beta2AR partial agonist.
Nat. Chem. Biol., 14, 2018
6B73
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BU of 6b73 by Molmil
Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor
Descriptor: CHOLESTEROL, N-[(5alpha,6beta)-17-(cyclopropylmethyl)-3-hydroxy-7,8-didehydro-4,5-epoxymorphinan-6-yl]-3-iodobenzamide, Nanobody, ...
Authors:Che, T, Majumdar, S, Zaidi, S.A, Kormos, C, McCorvy, J.D, Wang, S, Mosier, P.D, Uprety, R, Vardy, E, Krumm, B.E, Han, G.W, Lee, M.Y, Pardon, E, Steyaert, J, Huang, X.P, Strachan, R.T, Tribo, A.R, Pasternak, G.W, Carroll, I.F, Stevens, R.C, Cherezov, V, Katritch, V, Wacker, D, Roth, B.L.
Deposit date:2017-10-03
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Cell, 172, 2018
1ZMY
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BU of 1zmy by Molmil
cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme
Descriptor: Antibody cabbcII-10:lys3, Lysozyme C
Authors:Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K.
Deposit date:2005-05-11
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
J.Mol.Biol., 352, 2005
3CFI
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BU of 3cfi by Molmil
Nanobody-aided structure determination of the EPSI:EPSJ pseudopilin heterdimer from Vibrio Vulnificus
Descriptor: CHLORIDE ION, Nanobody NBEPSIJ_11, Type II secretory pathway, ...
Authors:Lam, A.Y, Pardon, E, Korotkov, K.V, Steyaert, J, Hol, W.G.J.
Deposit date:2008-03-03
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.
J.Struct.Biol., 166, 2009
3EZJ
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BU of 3ezj by Molmil
Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody
Descriptor: CHLORIDE ION, General secretion pathway protein GspD, NANOBODY NBGSPD_7, ...
Authors:Korotkov, K.V, Pardon, E, Steyaert, J, Hol, W.G.
Deposit date:2008-10-22
Release date:2009-02-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.
Structure, 17, 2009
8P8A
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BU of 8p8a by Molmil
Structure of 5D3-Fab and nanobody(Nb17)-bound ABCG2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ...
Authors:Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P.
Deposit date:2023-05-31
Release date:2023-08-30
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies.
J.Mol.Biol., 435, 2023
8P7W
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BU of 8p7w by Molmil
Structure of 5D3-Fab and nanobody(Nb8)-bound ABCG2
Descriptor: 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ATP-binding cassette sub-family G member 2, ...
Authors:Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P.
Deposit date:2023-05-31
Release date:2023-08-30
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies.
J.Mol.Biol., 435, 2023
8P8J
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BU of 8p8j by Molmil
Structure of 5D3-Fab and nanobody(Nb96)-bound ABCG2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ...
Authors:Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P.
Deposit date:2023-06-01
Release date:2023-08-30
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies.
J.Mol.Biol., 435, 2023
6VBG
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BU of 6vbg by Molmil
Lactose permease complex with thiodigalactoside and nanobody 9043
Descriptor: Galactoside permease, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose, nanobody 9043, ...
Authors:Kumar, H, Stroud, R.M, Kaback, H.R, Finer-Moore, J, Smirnova, I, Kasho, V, Pardon, E, Steyart, J.
Deposit date:2019-12-18
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Diversity in kinetics correlated with structure in nano body-stabilized LacY.
Plos One, 15, 2020
3P0G
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BU of 3p0g by Molmil
Structure of a nanobody-stabilized active state of the beta2 adrenoceptor
Descriptor: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor, Lysozyme, ...
Authors:Rasmussen, S.G.F, Choi, H.-J, Fung, J.J, Pardon, E, Casarosa, P, Chae, P.S, DeVree, B.T, Rosenbaum, D.M, Thian, F.S, Kobilka, T.S, Schnapp, A, Konetzki, I, Sunahara, R.K, Gellman, S.H, Pautsch, A, Steyaert, J, Weis, W.I, Kobilka, B.K.
Deposit date:2010-09-28
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
5BOP
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BU of 5bop by Molmil
Crystal structure of the artificial nanobody octarellinV.1 complex
Descriptor: Nanobody, Octarellin V.1
Authors:Figueroa, M, Sleutel, M, Pardon, E, Steyaert, J, Martial, J.A, van de Weerdt, C.
Deposit date:2015-05-27
Release date:2016-05-25
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
2X6M
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BU of 2x6m by Molmil
Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein
Descriptor: ALPHA-SYNUCLEIN PEPTIDE, HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY
Authors:DeGenst, E, Guilliams, T, Wellens, J, O'Day, E.M, Waudby, C.A, Meehan, S, Dumoulin, M, Hsu, S.-T.D, Cremades, N, Verschueren, K.H.G, Pardon, E, Wyns, L, Steyaert, J, Christodoulou, J, Dobson, C.M.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
2YPW
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BU of 2ypw by Molmil
Atomic model for the N-terminus of TraO fitted in the full-length structure of the bacterial pKM101 type IV secretion system core complex
Descriptor: TRAO
Authors:Rivera-Calzada, A, Fronzes, R, Savva, C.G, Chandran, V, Lian, P.W, Laeremans, T, Pardon, E, Steyaert, J, Remaut, H, Waksman, G, Orlova, E.V.
Deposit date:2012-11-02
Release date:2013-04-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (12.4 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
7B5G
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BU of 7b5g by Molmil
Crystal structure of E.coli LexA in complex with nanobody NbSOS3(Nb14527)
Descriptor: 1,2-ETHANEDIOL, LexA repressor, Nanobody Nb14527, ...
Authors:Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L.
Deposit date:2020-12-03
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway.
Structure, 30, 2022
5M95
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BU of 5m95 by Molmil
STAPHYLOCOCCUS CAPITIS DIVALENT METAL ION TRANSPORTER (DMT) IN COMPLEX WITH MANGANESE
Descriptor: CAMELID ANTIBODY FRAGMENT, NANOBODY, Divalent metal cation transporter MntH, ...
Authors:Ehrnstorfer, I.A, Geertsma, E.R, Pardon, E, Steyaert, J, Dutzler, R.
Deposit date:2016-10-31
Release date:2016-11-30
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure Of A Slc11 (Nramp) Transporter Reveals The Basis For Transition-Metal Ion Transport.
Nat.Struct.Mol.Biol., 21, 2014
5NBD
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BU of 5nbd by Molmil
PglK flippase in complex with inhibitory nanobody
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Nanobody, WlaB protein
Authors:Perez, C, Pardon, E, Steyaert, J, Locher, K.P.
Deposit date:2017-03-01
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.
Sci Rep, 7, 2017
3ZBI
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BU of 3zbi by Molmil
Fitting result in the O-layer of the subnanometer structure of the bacterial pKM101 type IV secretion system core complex digested with elastase
Descriptor: TRAF PROTEIN, TRAN PROTEIN, TRAO PROTEIN
Authors:Rivera-Calzada, A, Fronzes, R, Savva, C.G, Chandran, V, Lian, P.W, Laeremans, T, Pardon, E, Steyaert, J, Remaut, H, Waksman, G, Orlova, E.V.
Deposit date:2012-11-10
Release date:2013-04-03
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013

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