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Aspartylglucosaminuria mutant structure and function
Descriptor:	Glycosylasparaginase, residues 188-331, residues 38-178
Authors:	Pande, S, Laksminarasimhan, D, Guo, H.C.
Deposit date:	2018-05-13
Release date:	2018-08-01
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (1.63 Å)
Cite:	Biochemical and structural insights into an allelic variant causing the lysosomal storage disorder - aspartylglucosaminuria. FEBS Lett., 592, 2018

Structure & function of a new Aspartylglucosaminuria variant
Descriptor:	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase
Authors:	Pande, S, Guo, H.C.
Deposit date:	2019-01-19
Release date:	2019-04-17
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria. Protein Sci., 28, 2019

Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria
Descriptor:	Glycosylasparaginase
Authors:	Pande, S, Guo, H.
Deposit date:	2017-03-04
Release date:	2017-05-17
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.83 Å)
Cite:	Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminuria-causing mechanism as well as on hydrolysis of non-chitobiose substrate. Mol. Genet. Metab., 121, 2017

Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria
Descriptor:	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, N-hydroxy-L-asparagine
Authors:	Sui, L, Damodharan, L, Pande, S, Guo, H.C.
Deposit date:	2014-08-20
Release date:	2014-12-17
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural Basis of a Point Mutation that Causes the Genetic Disease Aspartylglucosaminuria. Structure, 22, 2014