Author results

6J8E
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HUMAN NAV1.2-BETA2-KIIIA TERNARY COMPLEX
Descriptor:Sodium channel subunit beta-2, Sodium channel protein type 2 subunit alpha, Mu-conotoxin KIIIA, ...
Authors:Pan, X., Li, Z., Huang, X., Huang, G., Yan, N.
Deposit date:2019-01-18
Release date:2019-02-27
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for pore blockade of human Na+channel Nav1.2 by the mu-conotoxin KIIIA.
Science, 363, 2019
5GHX
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CRYSTAL STRUCTURE OF BETA-LACTAMASE PENP MUTANT-E166H
Descriptor:Beta-lactamase, ACETIC ACID, 1,2-ETHANEDIOL
Authors:Pan, X., Zhao, Y.
Deposit date:2016-06-21
Release date:2017-01-25
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
5GHY
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CRYSTAL STRUCTURE OF BETA-LACTAMASE PENP MUTANT-E166H IN COMPLEX WITH CEPHALORIDINE AS "POST-ACYLATION" INTERMEDIATE
Descriptor:Beta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Authors:Pan, X., Zhao, Y.
Deposit date:2016-06-21
Release date:2017-01-25
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
5GHZ
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CRYSTAL STRUCTURE OF BETA-LACTAMASE PENP MUTANT-E166H IN COMPLEX WITH CEPHALORIDINE AS "PRE-DEACYLATION" INTERMEDIATE
Descriptor:Beta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Authors:Pan, X., Zhao, Y.
Deposit date:2016-06-21
Release date:2017-01-25
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
5ZFL
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CRYSTAL STRUCTURE OF BETA-LACTAMASE PENP MUTANT E166Y
Descriptor:Beta-lactamase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 1,2-ETHANEDIOL
Authors:Pan, X., Zhao, Y.
Deposit date:2018-03-06
Release date:2019-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Novel intermediates in the active site of Class A beta-lactamase reveal critical factors that coordinate the hydrolytic water molecule
To Be Published
5ZFT
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CRYSTAL STRUCTURE OF BETA-LACTAMASE PENP MUTANT-E166Y IN COMPLEX WITH CEPHALORIDINE AS "PRE-DEACYLATION" INTERMEDIATE
Descriptor:Beta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Authors:Pan, X., Zhao, Y.
Deposit date:2018-03-07
Release date:2019-03-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Novel intermediates in the active site of Class A beta-lactamase reveal critical factors that coordinate the hydrolytic water molecule
To Be Published
5ZG6
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CRYSTAL STRUCTURE OF BETA-LACTAMASE PENP MUTANT-E166Y IN COMPLEX WITH CEPHALORIDINE AS "POST-ACYLATION" INTERMEDIATE
Descriptor:Beta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Authors:Pan, X., Zhao, Y.
Deposit date:2018-03-07
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel intermediates in the active site of Class A beta-lactamase reveal critical factors that coordinate the hydrolytic water molecule
To Be Published
1NDQ
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BACILLUS LENTUS SUBTILISIN
Descriptor:Subtilisin Savinase, CALCIUM ION
Authors:Pan, X., Bott, R., Glatz, C.E.
Deposit date:2002-12-09
Release date:2004-04-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Subtilisin surface properties and crystal growth kinetics
J.CRYST.GROWTH, 254, 2003
1NDU
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BACILLUS LENTUS SUBTILISIN VARIANT S101G/V104N
Descriptor:Subtilisin Savinase, CALCIUM ION
Authors:Pan, X., Bott, R., Glatz, C.E.
Deposit date:2002-12-09
Release date:2004-04-06
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Subtilisin surface properties and crystal growth kinetics
J.CRYST.GROWTH, 254, 2003
2G77
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CRYSTAL STRUCTURE OF GYP1 TBC DOMAIN IN COMPLEX WITH RAB33 GTPASE BOUND TO GDP AND ALF3
Descriptor:GTPase-activating protein GYP1, Ras-related protein Rab-33B, MAGNESIUM ION, ...
Authors:Pan, X., Eathiraj, S., Munson, M., Lambright, D.G.
Deposit date:2006-02-27
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
Nature, 442, 2006
3JYL
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CRYSTAL STRUCTURES OF PSEUDOMONAS SYRINGAE PV. TOMATO DC3000 QUINONE OXIDOREDUCTASE
Descriptor:Quinone oxidoreductase
Authors:Pan, X., Zhang, H., Gao, Y., Li, M., Chang, W.
Deposit date:2009-09-22
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Pseudomonas syringae pv. tomato DC3000 quinone oxidoreductase and its complex with NADPH
Biochem.Biophys.Res.Commun., 390, 2009
3JYN
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CRYSTAL STRUCTURES OF PSEUDOMONAS SYRINGAE PV. TOMATO DC3000 QUINONE OXIDOREDUCTASE COMPLEXED WITH NADPH
Descriptor:Quinone oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Pan, X., Zhang, H., Gao, Y., Li, M., Chang, W.
Deposit date:2009-09-22
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structures of Pseudomonas syringae pv. tomato DC3000 quinone oxidoreductase and its complex with NADPH
Biochem.Biophys.Res.Commun., 390, 2009
4N92
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CRYSTAL STRUCTURE OF BETA-LACTAMSE PENP_E166S
Descriptor:Beta-lactamase
Authors:Pan, X., Wong, W., Zhao, Y.
Deposit date:2013-10-19
Release date:2014-09-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
4N9K
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CRYSTAL STRUCTURE OF BETA-LACTAMSE PENP_E166S IN COMPLEX WITH CEPHALORIDINE
Descriptor:Beta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Authors:Pan, X., Wong, W., Zhao, Y.
Deposit date:2013-10-21
Release date:2014-09-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
4N9L
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CRYSTAL STRUCTURE OF BETA-LACTAMSE PENP_E166S IN COMPLEX WITH MEROPENEM
Descriptor:Beta-lactamase, (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid
Authors:Pan, X., Wong, W., Zhao, Y.
Deposit date:2013-10-21
Release date:2014-09-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53, 2014
5XHR
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CRYSTAL STRUCTURE OF P99 BETA-LACTAMASE IN COMPLEX WITH A PENICILLIN DERIVATIVE MPC-1
Descriptor:Beta-lactamase, (2~{R},4~{S})-5,5-dimethyl-2-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-5-thiophen-2-yl-pentan-2-yl]-1,3-thiazolidine-4-carboxylic acid
Authors:Pan, X., Zhao, Y.
Deposit date:2017-04-24
Release date:2017-09-27
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases
Antimicrob. Agents Chemother., 61, 2017
6IJJ
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PHOTOSYSTEM I OF CHLAMYDOMONAS REINHARDTII
Descriptor:PsaA, PsaB, PsaC, ...
Authors:Pan, X., Ma, J., Su, X., Liu, Z., Zhang, X., Li, M.
Deposit date:2018-10-10
Release date:2019-03-20
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex.
Nat Plants, 5, 2019
6IJO
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PHOTOSYSTEM I OF CHLAMYDOMONAS REINHARDTII
Descriptor:PsaA, PsaB, PsaC, ...
Authors:Pan, X., Ma, J., Su, X., Liu, Z., Zhang, X., Li, M.
Deposit date:2018-10-10
Release date:2019-03-20
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex.
Nat Plants, 5, 2019
3QQ3
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CRYSTAL STRUCTURE OF SWINE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I SLA-1 0401 AND IDENTIFICATION OF 2009 PANDEMIC SWINE-ORIGIN INFLUENZA A H1N1 VIRUS CYTOTOXIC T LYMPHOCYTE EPITOPE PEPTIDES
Descriptor:MHC class I antigen, Beta-2-microglobulin, 9-mer peptide from Neuraminidase
Authors:Zhang, N., Qi, J., Gao, F., Pan, X., Chen, R., Li, Q., Chen, Z., Li, X., Xia, C., Gao, G.F.
Deposit date:2011-02-15
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides.
J.Virol., 85, 2011
3QQ4
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CRYSTAL STRUCTURE OF SWINE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I SLA-1 0401 AND IDENTIFICATION OF 2009 PANDEMIC SWINE-ORIGIN INFLUENZA A H1N1 VIRUS CYTOTOXIC T LYMPHOCYTE EPITOPE PEPTIDES
Descriptor:MHC class I antigen, Beta-2-microglobulin, VP35
Authors:Zhang, N., Qi, J., Gao, F., Pan, X., Chen, R., Li, Q., Chen, Z., Li, X., Xia, C., Gao, G.F.
Deposit date:2011-02-15
Release date:2011-12-28
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides.
J.Virol., 85, 2011
4IX3
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CRYSTAL STRUCTURE OF A STT7 HOMOLOG FROM MICROMONAS ALGAE
Descriptor:MsStt7d protein, MAGNESIUM ION
Authors:Guo, J., Wei, X., Li, M., Pan, X., Chang, W., Liu, Z.
Deposit date:2013-01-24
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae
Protein Cell, 4, 2013
4IX4
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CRYSTAL STRUCTURE OF A STT7 HOMOLOG FROM MICROMONAS ALGAE IN COMPLEX WITH ADP
Descriptor:MsStt7d protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Guo, J., Wei, X., Li, M., Pan, X., Chang, W., Liu, Z.
Deposit date:2013-01-24
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae
Protein Cell, 4, 2013
4IX5
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CRYSTAL STRUCTURE OF A STT7 HOMOLOG FROM MICROMONAS ALGAE IN COMPLEX WITH AMP-PNP
Descriptor:MsStt7d protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Guo, J., Wei, X., Li, M., Pan, X., Chang, W., Liu, Z.
Deposit date:2013-01-24
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae
Protein Cell, 4, 2013
4IX6
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CRYSTAL STRUCTURE OF A STT7 HOMOLOG FROM MICROMONAS ALGAE SOAKED WITH ATP
Descriptor:MsStt7d protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Guo, J., Wei, X., Li, M., Pan, X., Chang, W., Liu, Z.
Deposit date:2013-01-24
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae
Protein Cell, 4, 2013
1DJM
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SOLUTION STRUCTURE OF BEF3-ACTIVATED CHEY FROM ESCHERICHIA COLI
Descriptor:CHEMOTAXIS PROTEIN Y
Authors:Cho, H.S., Lee, S.Y., Yan, D., Pan, X., Parkinson, J.S., Kustu, S., Wemmer, D.E., Pelton, J.G.
Deposit date:1999-12-03
Release date:2000-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of activated CheY.
J.Mol.Biol., 297, 2000