Author results

2ILT
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HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE (HSD1) WITH NADP AND ADAMANTANE SULFONE INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NICKEL (II) ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Longenecker, K.L., Sorensen, B., Judge, R., Qin, W., Link, J.T.
Deposit date:2006-10-03
Release date:2007-04-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2IRW
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HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE (HSD1) WITH NADP AND ADAMANTANE ETHER INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE
Authors:Longenecker, K.L., Patel, J.R., Russell, J., Qin, W.
Deposit date:2006-10-16
Release date:2007-01-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 17, 2007
2KBQ
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SOLUTION STRUCTURE OF HARMONIN N TERMINAL DOMAIN
Descriptor:Harmonin
Authors:Zhang, M., Pan, L., Yan, J., Wu, L.
Deposit date:2008-12-05
Release date:2009-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
Proc.Natl.Acad.Sci.USA, 106, 2009
2KBR
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SOLUTION STRUCTURE OF HARMONIN N TERMINAL DOMAIN IN COMPLEX WITH A INTERNAL PEPTIDE OF CADHERIN23
Descriptor:Harmonin, 18-meric peptide from Cadherin-23
Authors:Pan, L., Yan, J., Wu, L., Zhang, M.
Deposit date:2008-12-05
Release date:2009-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
Proc.Natl.Acad.Sci.USA, 106, 2009
2KBS
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SOLUTION STRUCTURE OF HARMONIN PDZ2 IN COMPLEX WITH THE CARBOXYL TAIL PEPTIDE OF CADHERIN23
Descriptor:Harmonin, octameric peptide from Cadherin-23
Authors:Pan, L., Yan, J., Wu, L., Zhang, M.
Deposit date:2008-12-05
Release date:2009-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
Proc.Natl.Acad.Sci.USA, 106, 2009
2L7T
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SOLUTION STRUCTURE OF THE MFS-BOUND SANS CEN2 PEPTIDE
Descriptor:MFS-bound Sans CEN2 peptide
Authors:Pan, L., Wu, L., Wei, Z., Zhang, M.
Deposit date:2010-12-22
Release date:2011-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
2LD3
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SOLUTION STRUCTURE OF MYOSIN VI LEVER ARM EXTENSION
Descriptor:Myosin VI
Authors:Feng, W., Yu, C., Zhang, M.
Deposit date:2011-05-13
Release date:2012-05-16
Method:SOLUTION NMR
Cite:Membrane-induced lever arm expansion allows myosin VI to walk with large and variable step sizes
To be Published
2LSR
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SOLUTION STRUCTURE OF HARMONIN N TERMINAL DOMAIN IN COMPLEX WITH A EXON68 ENCODED PEPTIDE OF CADHERIN23
Descriptor:Harmonin, peptide from Cadherin-23
Authors:Pan, L., Wu, L., Zhang, C., Zhang, M.
Deposit date:2012-05-04
Release date:2012-08-15
Method:SOLUTION NMR
Cite:Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia
J.Biol.Chem., 2012
2MXP
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SOLUTION STRUCTURE OF NDP52 UBIQUITIN-BINDING ZINC FINGER
Descriptor:Calcium-binding and coiled-coil domain-containing protein 2, ZINC ION
Authors:Pan, L., Xie, X.
Deposit date:2015-01-12
Release date:2015-11-11
Method:SOLUTION NMR
Cite:Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2
Autophagy, 11, 2015
2PKU
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SOLUTION STRUCTURE OF PICK1 PDZ IN COMPLEX WITH THE CARBOXYL TAIL PEPTIDE OF GLUR2
Descriptor:PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE)
Authors:Pan, L., Wu, H., Shen, C., Shi, Y., Xia, J., Zhang, M.
Deposit date:2007-04-18
Release date:2007-11-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
Embo J., 26, 2007
3CYY
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THE CRYSTAL STRUCTURE OF ZO-1 PDZ2 IN COMPLEX WITH THE CX43 PEPTIDE
Descriptor:Tight junction protein ZO-1, peptide from Gap junction alpha-1 protein
Authors:Pan, L., Zhang, M.
Deposit date:2008-04-27
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
Embo J., 27, 2008
3HPK
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OXIDIZED DIMERIC PICK1 PDZ IN COMPLEX WITH THE CARBOXYL TAIL PEPTIDE OF GLUR2
Descriptor:PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT, GLYCEROL
Authors:Yu, J., Shi, Y., Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3HPM
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OXIDIZED DIMERIC PICK1 PDZ C46G MUTANT IN COMPLEX WITH THE CARBOXYL TAIL PEPTIDE OF GLUR2
Descriptor:PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
Authors:Yu, J., Shi, Y., Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3K1R
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STRUCTURE OF HARMONIN NPDZ1 IN COMPLEX WITH THE SAM-PBM OF SANS
Descriptor:Harmonin, Usher syndrome type-1G protein
Authors:Pan, L., Yan, J., Zhang, M.
Deposit date:2009-09-28
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins
Proc.Natl.Acad.Sci.USA, 107, 2010
3PVL
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STRUCTURE OF MYOSIN VIIA MYTH4-FERM-SH3 IN COMPLEX WITH THE CEN1 OF SANS
Descriptor:Myosin VIIa isoform 1, Usher syndrome type-1G protein, GLYCEROL, ...
Authors:Wu, L., Pan, L.F., Wei, Z.Y., Zhang, M.J.
Deposit date:2010-12-07
Release date:2011-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
3PZD
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STRUCTURE OF THE MYOSIN X MYTH4-FERM/DCC COMPLEX
Descriptor:Myosin-X, Netrin receptor DCC, GLYCEROL
Authors:Wei, Z., Yan, J., Pan, L., Zhang, M.
Deposit date:2010-12-14
Release date:2011-02-23
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q8T
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CRYSTAL STRUCTURE OF THE COILED COIL DOMAIN OF BECLIN 1, AN ESSENTIAL AUTOPHAGY PROTEIN
Descriptor:Beclin-1
Authors:Li, X., Zhao, Y.
Deposit date:2011-01-07
Release date:2012-01-18
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
Nat Commun, 3, 2012
3SHU
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CRYSTAL STRUCTURE OF ZO-1 PDZ3
Descriptor:Tight junction protein ZO-1
Authors:Yu, J., Pan, L., Chen, J., Yu, H., Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3SHW
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CRYSTAL STRUCTURE OF ZO-1 PDZ3-SH3-GUK SUPRAMODULE COMPLEX WITH CONNEXIN-45 PEPTIDE
Descriptor:Tight junction protein ZO-1, Gap junction gamma-1 protein
Authors:Yu, J., Pan, L., Chen, J., Yu, H., Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
4NFT
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CRYSTAL STRUCTURE OF HUMAN LNKH2B-H2A.Z-ANP32E
Descriptor:Histone H2B type 2-E, Histone H2A.Z, Acidic leucine-rich nuclear phosphoprotein 32 family member E
Authors:Shan, S., Pan, L., Mao, Z., Wang, W., Sun, J., Dong, Q., Liang, X., Ding, X., Chen, S., Dai, L., Zhang, Z., Zhu, B., Zhou, Z.
Deposit date:2013-11-01
Release date:2014-04-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
4XKL
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CRYSTAL STRUCTURE OF NDP52 ZF2 IN COMPLEX WITH MONO-UBIQUITIN
Descriptor:Ubiquitin, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL, ...
Authors:Xie, X., Li, F., Wang, Y., Lin, Z., Chen, X., Liu, J., Pan, L.
Deposit date:2015-01-12
Release date:2015-11-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2
Autophagy, 11, 2015
5BTU
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THE STRUCTURE OF DIELS-ALDERASE PYRI4 IN THE BIOSYNTHETIC PATHWAY OF PYRROINDOMYCINS
Descriptor:PyrI4, GLYCEROL, DI(HYDROXYETHYL)ETHER
Authors:Pan, L., Guo, Y., Liu, J.
Deposit date:2015-06-03
Release date:2016-02-24
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4
Cell Chem Biol, 23, 2016
5BU3
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CRYSTAL STRUCTURE OF DIELS-ALDERASE PYRI4 IN COMPLEX WITH ITS PRODUCT
Descriptor:PyrI4, GLYCEROL, (4S,4aS,6aS,8R,9R,10aR,13R,14aS,18aR,18bR)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,5,6,6a,7,8,9,10,10a,13,14,18a,18b-hexadecahydro-1H-14a,17-(metheno)benzo[b]naphtho[2,1-h]azacyclododecine-16,18(15H,17H)-dione
Authors:Pan, L., Guo, Y., Liu, J.
Deposit date:2015-06-03
Release date:2016-02-24
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4
Cell Chem Biol, 23, 2016
5CHL
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STRUCTURAL BASIS OF H2A.Z RECOGNITION BY YL1 HISTONE CHAPERONE COMPONENT OF SRCAP/SWR1 CHROMATIN REMODELING COMPLEX
Descriptor:Vacuolar protein sorting-associated protein 72 homolog, Histone H2A.Z
Authors:Shan, S., Liang, X., Pan, L., Wu, C., Zhou, Z.
Deposit date:2015-07-10
Release date:2016-03-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
5CX3
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CRYSTAL STRUCTURE OF FYCO1 LIR IN COMPLEX WITH LC3A
Descriptor:Microtubule-associated proteins 1A/1B light chain 3A, FYVE and coiled-coil domain-containing protein 1, GLYCEROL
Authors:Cheng, X., Pan, L.
Deposit date:2015-07-28
Release date:2016-08-03
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins.
Autophagy, 12, 2016
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