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2NEF
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BU of 2nef by Molmil
HIV-1 NEF (REGULATORY FACTOR), NMR, 40 STRUCTURES
Descriptor: NEGATIVE FACTOR (F-PROTEIN)
Authors:Grzesiek, S, Bax, A, Clore, G.M, Gronenborn, A.M, Hu, J.S, Kaufman, J, Palmer, I, Stahl, S.J, Tjandra, N, Wingfield, P.T.
Deposit date:1997-02-12
Release date:1997-07-07
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Refined solution structure and backbone dynamics of HIV-1 Nef.
Protein Sci., 6, 1997
4HLA
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BU of 4hla by Molmil
Crystal structure of wild type HIV-1 protease in complex with darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease
Authors:Yedidi, R.S, Garimella, H, Palmer, I, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H.
Deposit date:2012-10-16
Release date:2013-07-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Antimicrob.Agents Chemother., 57, 2013
4I8W
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BU of 4i8w by Molmil
Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL007
Descriptor: 4-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-2-hydroxy-4-phenylbutyl](2-methylpropyl)sulfamoyl}benzoic acid, Protease
Authors:Yedidi, R.S, Palmer, I, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H.
Deposit date:2012-12-04
Release date:2013-07-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Antimicrob.Agents Chemother., 57, 2013
4I8Z
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BU of 4i8z by Molmil
Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL008
Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-carbamoylphenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease
Authors:Yedidi, R.S, Palmer, I, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H.
Deposit date:2012-12-04
Release date:2013-07-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Antimicrob.Agents Chemother., 57, 2013
1D8V
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BU of 1d8v by Molmil
THE RESTRAINED AND MINIMIZED AVERAGE NMR STRUCTURE OF MAP30.
Descriptor: ANTI-HIV AND ANTI-TUMOR PROTEIN MAP30
Authors:Wang, Y.-X, Neamati, N, Jacob, J, Palmer, I, Stahl, S.J.
Deposit date:1999-10-26
Release date:1999-11-19
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions.
Cell(Cambridge,Mass.), 99, 1999
7U0F
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BU of 7u0f by Molmil
HIV-1 Rev in complex with tubulin
Descriptor: Protein Rev, Tubulin alpha-1A chain, Tubulin beta chain
Authors:Eren, E.
Deposit date:2022-02-18
Release date:2023-08-23
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
Structure, 31, 2023
1AVZ
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BU of 1avz by Molmil
V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN
Descriptor: FYN TYROSINE KINASE, NEGATIVE FACTOR
Authors:Arold, S, Franken, P, Dumas, C.
Deposit date:1997-09-23
Release date:1998-03-25
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997
1AVV
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BU of 1avv by Molmil
HIV-1 NEF PROTEIN, UNLIGANDED CORE DOMAIN
Descriptor: NEGATIVE FACTOR
Authors:Arold, S, Franken, P, Dumas, C.
Deposit date:1997-09-21
Release date:1998-03-25
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997
1QA5
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BU of 1qa5 by Molmil
MYRISTOYLATED HIV-1 NEF ANCHOR DOMAIN, NMR, 2 STRUCTURES
Descriptor: PROTEIN (MYRISTOYLATED HIV-1 NEF ANCHOR DOMAIN (MYRISTATE-GLY2 TO TRP57))
Authors:Geyer, M, Kalbitzer, H.R.
Deposit date:1999-04-12
Release date:1999-05-26
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
J.Mol.Biol., 289, 1999
1QA4
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BU of 1qa4 by Molmil
HIV-1 NEF ANCHOR DOMAIN, NMR, 2 STRUCTURES
Descriptor: Protein Nef
Authors:Geyer, M, Kalbitzer, H.R.
Deposit date:1999-04-12
Release date:1999-05-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
J.Mol.Biol., 289, 1999
2X7L
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BU of 2x7l by Molmil
Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV
Authors:DiMattia, M.A, Watts, N.R, Stahl, S.J, Rader, C, Wingfield, P.T, Stuart, D.I, Steven, A.C, Grimes, J.M.
Deposit date:2010-03-01
Release date:2010-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element.
Proc.Natl.Acad.Sci.USA, 107, 2010
1EFN
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BU of 1efn by Molmil
HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
Descriptor: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1996-06-29
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996

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PDB entries from 2024-03-27

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