Author results

1MUE
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THROMBIN-HIRUGEN-L405,426
Descriptor:THROMBIN, HIRUDIN IIB, 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE
Authors:Burgey, C.S., Robinson, K.A., Lyle, T.A., Nantermet, P.G., Selnick, H.G., Isaacs, R.C., Lewis, S.D., Lucas, B.J., Krueger, J.A., Singh, R., Miller-Stein, C., White, R.B., Wong, B., Lyle, E.A., Stranieri, M.T., Cook, J.J., McMasters, D.R., Pellicore, J.M., Pal, S., Wallace, A.A., Clayton, F.C., Bohn, D., Welsh, D.C., Lynch, J.J., Yan, Y., Chen, Z., Kuo, L., Gardell, S.J., Shafer, J.A., Vacca, J.P.
Deposit date:2002-09-23
Release date:2004-04-06
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides.
Bioorg.Med.Chem.Lett., 13, 2003
5D7B
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TRIGONAL CRYSTAL STRUCTURE OF AN ACETYLESTER HYDROLASE FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:Homoserine O-acetyltransferase, GLYCEROL
Authors:Niefind, K., Toelzer, C., Pal, S., Altenbuchner, J., Watzlawick, H.
Deposit date:2015-08-13
Release date:2015-12-16
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases.
Febs Lett., 590, 2016
5E4Y
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ORTHORHOMBIC STRUCTURE OF THE ACETYL ESTERASE MEKB
Descriptor:Homoserine O-acetyltransferase
Authors:Niefind, K., Toelzer, C., Pal, S., Watzlawick, H., Altenbuchner, J.
Deposit date:2015-10-07
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases.
Febs Lett., 590, 2016
5EFZ
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MONOCLINIC STRUCTURE OF THE ACETYL ESTERASE MEKB
Descriptor:Homoserine O-acetyltransferase, 1,2-ETHANEDIOL, GLYCEROL, ...
Authors:Toelzer, C., Pal, S., Watzlawick, H., Altenbuchner, J., Niefind, K.
Deposit date:2015-10-26
Release date:2015-12-16
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases.
Febs Lett., 590, 2016
5F6Z
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SANDERCYANIN FLUORESCENT PROTEIN PURIFIED FROM SANDER VITREUS
Descriptor:Sandercyanin Fluorescent Protein, BILIVERDINE IX ALPHA, N-ACETYL-D-GLUCOSAMINE
Authors:Ghosh, S., Yu, C.L., Ferraro, D., Sudha, S., Pal, S., Schaefer, W., Gibson, D.T., Subramanian, R.
Deposit date:2015-12-07
Release date:2016-09-28
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Blue protein with red fluorescence
Proc.Natl.Acad.Sci.USA, 113, 2016
5D6O
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ORTHORHOMBIC CRYSTAL STRUCTURE OF AN ACETYLESTER HYDROLASE FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor:Homoserine O-acetyltransferase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Niefind, K., Toelzer, C., Altenbuchner, J., Watzlawick, H.
Deposit date:2015-08-12
Release date:2015-12-09
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases.
Febs Lett., 590, 2016
5N7T
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PSEUDOMONAS FLUORESCENS KYNURENINE 3-MONOOXYGENASE (KMO) IN COMPLEX WITH 3-(5,6-DICHLORO-2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-3-YL)PROPANOIC ACID
Descriptor:Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ...
Authors:Rowland, P.
Deposit date:2017-02-21
Release date:2017-06-14
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.
Bioorg. Med. Chem. Lett., 27, 2017