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5V89
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BU of 5v89 by Molmil
Structure of DCN4 PONY domain bound to CUL1 WHB
Descriptor: Cullin-1, DCN1-like protein 4
Authors:Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T.
Deposit date:2017-03-21
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Nat. Chem. Biol., 13, 2017
5V83
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BU of 5v83 by Molmil
Structure of DCN1 bound to NAcM-HIT
Descriptor: Lysozyme,DCN1-like protein 1 chimera, N-(1-benzylpiperidin-4-yl)-N'-[3-(trifluoromethyl)phenyl]urea
Authors:Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T.
Deposit date:2017-03-21
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Nat. Chem. Biol., 13, 2017
5V86
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BU of 5v86 by Molmil
Structure of DCN1 bound to NAcM-OPT
Descriptor: Lysozyme,DCN1-like protein 1, N-benzyl-N-(1-butylpiperidin-4-yl)-N'-(3,4-dichlorophenyl)urea
Authors:Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T.
Deposit date:2017-03-21
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.374 Å)
Cite:Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Nat. Chem. Biol., 13, 2017
5V88
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BU of 5v88 by Molmil
Structure of DCN1 bound to NAcM-COV
Descriptor: Lysozyme,DCN1-like protein 1, N-{2-[({1-[(2R)-pentan-2-yl]piperidin-4-yl}{[3-(trifluoromethyl)phenyl]carbamoyl}amino)methyl]phenyl}propanamide
Authors:Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T.
Deposit date:2017-03-21
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.
Nat. Chem. Biol., 13, 2017
3VKX
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BU of 3vkx by Molmil
Structure of PCNA
Descriptor: 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ...
Authors:Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N.
Deposit date:2011-11-26
Release date:2012-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication
J.Biol.Chem., 287, 2012

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