Author results

1JPJ
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GMPPNP COMPLEX OF SRP GTPASE NG DOMAIN
Descriptor:SIGNAL RECOGNITION PARTICLE PROTEIN, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Padmanabhan, S., Freymann, D.M.
Deposit date:2001-08-02
Release date:2002-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The conformation of bound GMPPNP suggests a mechanism for gating the active site of the SRP GTPase.
Structure, 9, 2001
1JPN
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GMPPNP COMPLEX OF SRP GTPASE NG DOMAIN
Descriptor:SIGNAL RECOGNITION PARTICLE PROTEIN, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Padmanabhan, S., Freymann, D.M.
Deposit date:2001-08-02
Release date:2002-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The conformation of bound GMPPNP suggests a mechanism for gating the active site of the SRP GTPase.
Structure, 9, 2001
1ZUG
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STRUCTURE OF PHAGE 434 CRO PROTEIN, NMR, 20 STRUCTURES
Descriptor:PHAGE 434 CRO PROTEIN
Authors:Padmanabhan, S., Jimenez, M.A., Gonzalez, C., Sanz, J.M., Gimenez-Gallego, G., Rico, M.
Deposit date:1997-03-14
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and stability of phage 434 Cro protein.
Biochemistry, 36, 1997
2EA1
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CRYSTAL STRUCTURE OF RIBONUCLEASE I FROM ESCHERICHIA COLI COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE
Descriptor:Ribonuclease I, GUANYLYL-2',5'-PHOSPHOGUANOSINE
Authors:Zhou, K., Pan, J., Padmanabhan, S., Lim, R.W., Lim, L.W.
Deposit date:2007-01-29
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Ribonuclease I from Escherichia Coli Complexed with Guanylyl-2(Prime),5(Prime)-Guanosine at 1.80 Angstroms Resolution
To be Published
2KSS
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NMR STRUCTURE OF MYXOCOCCUS XANTHUS ANTIREPRESSOR CARS1
Descriptor:Carotenogenesis protein carS
Authors:Jimenez, M., Gonzalez, C., Padmanabhan, S., Leon, E., Navarro-Aviles, G., Elias-Arnanz, M.
Deposit date:2010-01-13
Release date:2010-05-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A bacterial antirepressor with SH3 domain topology mimics operator DNA in sequestering the repressor DNA recognition helix.
Nucleic Acids Res., 38, 2010
2LT3
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SOLUTION NMR STRUCTURE OF THE C-TERMINAL DOMAIN OF CDNL FROM MYXOCOCCUS XANTHUS
Descriptor:Transcriptional regulator, CarD family
Authors:Mirassou, Y., Garcia-Moreno, D., Padmanabhan, S., Jimenez, M.A.
Deposit date:2012-05-14
Release date:2013-11-13
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:Structural Insights into RNA Polymerase Recognition and Essential Function of Myxococcus xanthus CdnL.
Plos One, 9, 2014
2LT4
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CDNLNT FROM MYXOCCOCCUS XANTHUS
Descriptor:Transcriptional regulator, CarD family
Authors:Jimenez, M.A., Padmanabhan, S., Mirassou, Y.
Deposit date:2012-05-14
Release date:2013-11-13
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:Structural Insights into RNA Polymerase Recognition and Essential Function of Myxococcus xanthus CdnL.
Plos One, 9, 2014
2LWJ
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NMR SOLUTION STRUCTURE MYXOCCOCCUS XANTHUS CDNL
Descriptor:Transcriptional regulator, CarD family
Authors:Jimenez, M., Padmanabhan, S., Mirassou, Y.
Deposit date:2012-08-01
Release date:2014-02-05
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:Structural Insights into RNA Polymerase Recognition and Essential Function of Myxococcus xanthus CdnL.
Plos One, 9, 2014
1BF4
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CHROMOSOMAL DNA-BINDING PROTEIN SSO7D/D(GCGAACGC) COMPLEX
Descriptor:DNA (5'-D(*GP*CP*GP*TP*5IUP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*AP*AP*CP*GP*C)-3'), PROTEIN (CHROMOSOMAL PROTEIN SSO7D)
Authors:Su, S., Gao, Y.-G., Robinson, H., Padmanabhan, S., Lim, L., Shriver, J.W., Wang, A.H.-J.
Deposit date:1998-05-27
Release date:1999-11-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA.
Nat.Struct.Biol., 5, 1998
1BNZ
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SSO7D HYPERTHERMOPHILE PROTEIN/DNA COMPLEX
Descriptor:5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-BINDING PROTEIN 7A
Authors:Gao, Y.-G., Su, S.-Y., Robinson, H., Padmanabhan, S., Lim, L., Mccrary, B.S., Edmondos, S.P., Shrive, J.W., Wang, A.H.-J.
Deposit date:1998-07-31
Release date:1998-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA.
Nat.Struct.Biol., 5, 1998
2JML
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF CARA REPRESSOR
Descriptor:DNA BINDING DOMAIN/TRANSCRIPTIONAL REGULATOR
Authors:Jimenez, M., Padmanabhan, S., Gonzalez, C., Perez-Marin, M.C., Elias-Arnanz, M., Murillo, F.J., Rico, M.
Deposit date:2006-11-20
Release date:2007-02-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for operator and antirepressor recognition by Myxococcus xanthus CarA repressor.
Mol.Microbiol., 63, 2007
2LQK
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NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE CDNL PROTEIN FROM THERMUS THERMOPHILUS
Descriptor:Transcriptional regulator
Authors:Jimenez, M., Padmanabhan, S.
Deposit date:2012-03-09
Release date:2012-08-01
Last modified:2012-08-08
Method:SOLUTION NMR
Cite:NMR structure note: N-terminal domain of Thermus thermophilus CdnL.
J.Biomol.Nmr, 53, 2012
2LT1
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SOLUTION NMR STRUCTURE OF THE 72-RESIDUE N-TERMINAL DOMAIN OF MYXOCOCCUS XANTHUS CARD
Descriptor:CarD protein
Authors:Jimenez, M.A., Padmanabhan, S.
Deposit date:2012-05-10
Release date:2013-11-13
Last modified:2015-04-08
Method:SOLUTION NMR
Cite:Structure-Function Dissection of Myxococcus xanthus CarD N-Terminal Domain, a Defining Member of the CarD_CdnL_TRCF Family of RNA Polymerase Interacting Proteins.
Plos One, 10
5VLR
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CRYSTAL STRUCTURE OF PI3K DELTA IN COMPLEX WITH A TRIFLUORO-ETHYL-PYRAZOL-PYROLOTRIAZINE INHIBITOR
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, 4-acetyl-1-(3-{4-amino-5-[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-7-yl}phenyl)-3,3-dimethylpiperazin-2-one
Authors:Sack, J.S.
Deposit date:2017-04-26
Release date:2017-06-07
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase delta (PI3K delta ) Inhibitor for the Treatment of Immunological Disorders.
J. Med. Chem., 60, 2017
5C8A
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CRYSTAL STRUCTURE OF A TRUNCATED FORM OF THERMUS THERMOPHILUS CARH BOUND TO ADENOSYLCOBALAMIN (DARK STATE)
Descriptor:Light-dependent transcriptional regulator CarH, COBALAMIN, 5'-DEOXYADENOSINE, ...
Authors:Jost, M., Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
5C8D
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CRYSTAL STRUCTURE OF FULL-LENGTH THERMUS THERMOPHILUS CARH BOUND TO ADENOSYLCOBALAMIN (DARK STATE)
Descriptor:Light-dependent transcriptional regulator CarH, COBALAMIN, 5'-DEOXYADENOSINE
Authors:Jost, M., Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
5C8E
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS CARH BOUND TO ADENOSYLCOBALAMIN AND A 26-BP DNA SEGMENT
Descriptor:Light-dependent transcriptional regulator CarH, 26-mer DNA segment containing the CarH operator sequence (antisense strand), 26-mer DNA segment containing the CarH operator sequence (sense strand), ...
Authors:Jost, M., Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
5C8F
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CRYSTAL STRUCTURE OF LIGHT-EXPOSED FULL-LENGTH THERMUS THERMOPHILUS CARH BOUND TO COBALAMIN
Descriptor:Light-dependent transcriptional regulator CarH, COBALAMIN, CHLORIDE ION, ...
Authors:Jost, M., Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
1CA5
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INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA
Descriptor:5'-D(*GP*TP*GP*AP*TP*CP*AP*C)-3', CHROMOSOMAL PROTEIN SAC7D
Authors:Su, S., Gao, Y.-G., Robinson, H., Shriver, J.W., Wang, A.H.-J.
Deposit date:1999-02-23
Release date:2000-02-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs
J.Mol.Biol., 303, 2000
1CA6
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INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA
Descriptor:5'-D(*GP*TP*GP*AP*TP*CP*GP*C)-3', CHROMOSOMAL PROTEIN SAC7D
Authors:Su, S., Gao, Y.-G., Robinson, H., Shriver, J.W., Wang, A.H.-J.
Deposit date:1999-02-23
Release date:2000-02-23
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs
J.Mol.Biol., 303, 2000
1OKK
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HOMO-HETERODIMERIC COMPLEX OF THE SRP GTPASES
Descriptor:SIGNAL RECOGNITION PARTICLE PROTEIN, CELL DIVISION PROTEIN FTSY, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Focia, P.J., Freymann, D.M.
Deposit date:2003-07-26
Release date:2004-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Heterodimeric Gtpase Core of the Srp Targeting Complex
Science, 303, 2004