Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1D0D
DownloadVisualize
BU of 1d0d by Molmil
CRYSTAL STRUCTURE OF TICK ANTICOAGULANT PROTEIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor: ANTICOAGULANT PROTEIN, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION
Authors:St.Charles, R, Padmanabhan, K, Arni, R.V, Padmanabhan, K.P, Tulinsky, A.
Deposit date:1999-09-09
Release date:2000-09-09
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure of tick anticoagulant peptide at 1.6 A resolution complexed with bovine pancreatic trypsin inhibitor.
Protein Sci., 9, 2000
1HUT
DownloadVisualize
BU of 1hut by Molmil
THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER
Descriptor: ALPHA-Thrombin heavy chain, ALPHA-Thrombin light chain, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
Authors:Padmanabhan, K, Padmanabhan, K.P, Ferrara, J.D, Sadler, J.E, Tulinsky, A.
Deposit date:1993-05-27
Release date:1994-06-22
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.
J.Biol.Chem., 268, 1993
1THS
DownloadVisualize
BU of 1ths by Molmil
STRUCTURES OF THROMBIN COMPLEXES WITH A DESIGNED AND A NATURAL EXOSITE INHIBITOR
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), SYNTHETIC INHIBITOR
Authors:Qiu, X, Yin, M, Padmanabhan, K.P, Krstenansky, J.L, Tulinsky, A.
Deposit date:1993-06-16
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
J.Biol.Chem., 268, 1993
1THR
DownloadVisualize
BU of 1thr by Molmil
STRUCTURES OF THROMBIN COMPLEXES WITH A DESIGNED AND A NATURAL EXOSITE INHIBITOR
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRULLIN
Authors:Qiu, X, Yin, M, Padmanabhan, K.P, Krstenansky, J.L, Tulinsky, A.
Deposit date:1993-06-16
Release date:1994-01-31
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
J.Biol.Chem., 268, 1993
1TMB
DownloadVisualize
BU of 1tmb by Molmil
MOLECULAR BASIS FOR THE INHIBITION OF HUMAN ALPHA-THROMBIN BY THE MACROCYCLIC PEPTIDE CYCLOTHEONAMIDE A
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ...
Authors:Qiu, X, Padmanabhan, K.P, Maryanoff, B.E, Tulinsky, A.
Deposit date:1993-05-27
Release date:1994-01-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A.
Proc.Natl.Acad.Sci.USA, 90, 1993
2HPQ
DownloadVisualize
BU of 2hpq by Molmil
Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1993-04-28
Release date:1994-01-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Biochemistry, 32, 1993
2HPP
DownloadVisualize
BU of 2hpp by Molmil
Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human ppack-thrombin
Descriptor: ALPHA-THROMBIN HEAVY CHAIN, ALPHA-THROMBIN LIGHT CHAIN, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1993-04-28
Release date:1994-01-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Biochemistry, 32, 1993
4DII
DownloadVisualize
BU of 4dii by Molmil
X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F.
Deposit date:2012-01-31
Release date:2012-07-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity.
Nucleic Acids Res., 40, 2012
4DIH
DownloadVisualize
BU of 4dih by Molmil
X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of sodium ions
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F.
Deposit date:2012-01-31
Release date:2012-07-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity.
Nucleic Acids Res., 40, 2012
1ABJ
DownloadVisualize
BU of 1abj by Molmil
STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
Authors:Qiu, X, Tulinsky, A.
Deposit date:1992-08-24
Release date:1994-01-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
Biochemistry, 31, 1992
1A4W
DownloadVisualize
BU of 1a4w by Molmil
CRYSTAL STRUCTURES OF THROMBIN WITH THIAZOLE-CONTAINING INHIBITORS: PROBES OF THE S1' BINDING SITE
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ...
Authors:Matthews, J.H, Krishnan, R, Costanzo, M.J, Maryanoff, B.E, Tulinsky, A.
Deposit date:1998-02-06
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.
Biophys.J., 71, 1996
1ABI
DownloadVisualize
BU of 1abi by Molmil
STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRULOG 3
Authors:Qiu, X, Tulinsky, A.
Deposit date:1992-08-24
Release date:1994-01-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
Biochemistry, 31, 1992
1HAP
DownloadVisualize
BU of 1hap by Molmil
COMPLEX OF HUMAN ALPHA-THROMBIN WITH A 15MER OLIGONUCLEOTIDE GGTTGGTGTGGTTGG (BASED ON X-RAY MODEL OF DNA)
Descriptor: 5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3', D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ...
Authors:Padmanabhan, K, Tulinsky, A.
Deposit date:1995-10-03
Release date:1996-04-03
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An ambiguous structure of a DNA 15-mer thrombin complex.
Acta Crystallogr.,Sect.D, 52, 1996
1HAO
DownloadVisualize
BU of 1hao by Molmil
COMPLEX OF HUMAN ALPHA-THROMBIN WITH A 15MER OLIGONUCLEOTIDE GGTTGGTGTGGTTGG (BASED ON NMR MODEL OF DNA)
Descriptor: ALPHA-THROMBIN heavy chain, ALPHA-THROMBIN light chain, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1995-10-03
Release date:1996-04-03
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An ambiguous structure of a DNA 15-mer thrombin complex.
Acta Crystallogr.,Sect.D, 52, 1996
1ADZ
DownloadVisualize
BU of 1adz by Molmil
THE SOLUTION STRUCTURE OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR, NMR, 30 STRUCTURES
Descriptor: TISSUE FACTOR PATHWAY INHIBITOR
Authors:Burgering, M.J.M, Orbons, L.P.M.
Deposit date:1997-02-19
Release date:1998-02-25
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
J.Mol.Biol., 269, 1997
2HNT
DownloadVisualize
BU of 2hnt by Molmil
CRYSTALLOGRAPHIC STRUCTURE OF HUMAN GAMMA-THROMBIN
Descriptor: GAMMA-THROMBIN
Authors:Tulinsky, A.
Deposit date:1994-08-23
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic structure of human gamma-thrombin.
J.Biol.Chem., 269, 1994
1HCG
DownloadVisualize
BU of 1hcg by Molmil
STRUCTURE OF HUMAN DES(1-45) FACTOR XA AT 2.2 ANGSTROMS RESOLUTION
Descriptor: BLOOD COAGULATION FACTOR XA
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1993-05-05
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human des(1-45) factor Xa at 2.2 A resolution.
J.Mol.Biol., 232, 1993
1HAH
DownloadVisualize
BU of 1hah by Molmil
THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:Tulinsky, A, Vijayalakshmi, J.
Deposit date:1994-06-27
Release date:1994-12-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3, 1994
1HAG
DownloadVisualize
BU of 1hag by Molmil
THE ISOMORPHOUS STRUCTURES OF PRETHROMBIN2, HIRUGEN-AND PPACK-THROMBIN: CHANGES ACCOMPANYING ACTIVATION AND EXOSITE BINDING TO THROMBIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUGEN, PRETHROMBIN 2
Authors:Tulinsky, A, Vijayalakshmi, J.
Deposit date:1994-06-27
Release date:1994-12-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Protein Sci., 3, 1994
1TBZ
DownloadVisualize
BU of 1tbz by Molmil
HUMAN THROMBIN WITH ACTIVE SITE N-METHYL-D PHENYLALANYL-N-[5-(AMINOIMINOMETHYL)AMINO]-1-{{BENZOTHIAZOLYL)CARBONYL] BUTYL]-L-PROLINAMIDE TRIFLUROACETATE AND EXOSITE-HIRUGEN
Descriptor: ALPHA-THROMBIN, D-phenylalanyl-N-{(1S)-1-[(S)-1,3-benzothiazol-2-yl(hydroxy)methyl]-4-carbamimidamidobutyl}-L-prolinamide, HIRUGEN, ...
Authors:Matthews, J.H, Krishnan, R, Costanzo, M.J, Maryanoff, B.E, Tulinsky, A.
Deposit date:1998-02-05
Release date:1998-05-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.
Biophys.J., 71, 1996
1FAX
DownloadVisualize
BU of 1fax by Molmil
COAGULATION FACTOR XA INHIBITOR COMPLEX
Descriptor: (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid, CALCIUM ION, FACTOR XA
Authors:Brandstetter, H, Engh, R.A.
Deposit date:1996-08-23
Release date:1997-10-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition.
J.Biol.Chem., 271, 1996
1NRS
DownloadVisualize
BU of 1nrs by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUGEN, ...
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRR
DownloadVisualize
BU of 1nrr by Molmil
Crystallographic structures of Thrombin complexed with Thrombin receptor peptides: Existence of expected and novel binding modes
Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Proteinase-activated receptor 1, Thrombin heavy chain, ...
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRN
DownloadVisualize
BU of 1nrn by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRS
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
1NRO
DownloadVisualize
BU of 1nro by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NRP
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon