Author results

1HES
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH P-SELECTIN INTERNALIZATION PEPTIDE SHLGTYGVFTNAA
Descriptor:CLATHRIN COAT ASSEMBLY PROTEIN AP50, P-SELECTIN PEPTIDE
Authors:Owen, D.J., Evans, P.R., Green, S.A.
Deposit date:2000-11-24
Release date:2001-05-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Third Specificity-Determining Site in Mu 2 Adaptin for Sequences Upstream of Yxx Phi Sorting Motifs
Traffic, 2, 2001
1PHK
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TWO STRUCTURES OF THE CATALYTIC DOMAIN OF PHOSPHORYLASE, KINASE: AN ACTIVE PROTEIN KINASE COMPLEXED WITH NUCLEOTIDE, SUBSTRATE-ANALOGUE AND PRODUCT
Descriptor:PHOSPHORYLASE KINASE, MANGANESE (II) ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Owen, D.J., Noble, M.E.M., Garman, E.F., Papageorgiou, A.C., Johnson, L.N.
Deposit date:1996-03-15
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product.
Structure, 3, 1995
1B9K
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ALPHA-ADAPTIN APPENDAGE DOMAIN, FROM CLATHRIN ADAPTOR AP2
Descriptor:PROTEIN (ALPHA-ADAPTIN APPENDAGE DOMAIN)
Authors:Owen, D.J., Evans, P.R.
Deposit date:1999-02-11
Release date:1999-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.
Cell(Cambridge,Mass.), 97, 1999
1BB9
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CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM RAT AMPHIPHYSIN 2
Descriptor:AMPHIPHYSIN 2
Authors:Owen, D.J., Mcmahon, H.T., Evans, P.R.
Deposit date:1998-04-29
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.
EMBO J., 17, 1998
1BW8
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM
Descriptor:PROTEIN (MU2 ADAPTIN SUBUNIT), PROTEIN (INTERNALIZATION SIGNAL FROM EGFR)
Authors:Owen, D.J., Evans, P.R.
Deposit date:1998-09-30
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A structural explanation for the recognition of tyrosine-based endocytotic signals.
Science, 282, 1998
1BXX
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH TGN38 INTERNALIZATION PEPTIDE DYQRLN
Descriptor:PROTEIN (AP50), PROTEIN (TGN38 PEPTIDE)
Authors:Owen, D.J., Evans, P.R.
Deposit date:1998-10-08
Release date:1998-11-25
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural explanation for the recognition of tyrosine-based endocytotic signals.
Science, 282, 1998
1E42
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BETA2-ADAPTIN APPENDAGE DOMAIN, FROM CLATHRIN ADAPTOR AP2
Descriptor:AP-2 COMPLEX SUBUNIT BETA, DITHIANE DIOL, MAGNESIUM ION, ...
Authors:Owen, D.J., Evans, P.R., McMahon, H.T.
Deposit date:2000-06-27
Release date:2000-08-21
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structure and Function of the Beta2-Adaptin Appendage Domain
Embo J., 19, 2000
1E6I
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BROMODOMAIN FROM GCN5 COMPLEXED WITH ACETYLATED H4 PEPTIDE
Descriptor:TRANSCRIPTIONAL ACTIVATOR GCN5, HISTONE H4
Authors:Owen, D.J., Travers, A.A., Evans, P.R.
Deposit date:2000-08-18
Release date:2000-11-24
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Structural Basis for the Recognition of Acetylated Histone H4 by the Bromodomain of Histone Acetyltransferase Gcn5P
Embo J., 19, 2000
5C7Z
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AP2 MU2 ADAPTIN C-TERMINAL DOMAIN COMPLEXED WITH INTEGRIN ALPHA-4 PEPTIDE
Descriptor:AP-2 complex subunit mu, Integrin alpha-4
Authors:Owen, D.J., Evans, P.R., Wilson, T.A.
Deposit date:2015-06-25
Release date:2016-07-06
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
2JKR
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AP2 CLATHRIN ADAPTOR CORE WITH DILEUCINE PEPTIDE RM(PHOSPHOS)QIKRLLSE
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT SIGMA-1, ...
Authors:Owen, D.J., McCoy, A.J., Kelly, B.T., Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKT
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AP2 CLATHRIN ADAPTOR CORE WITH CD4 DILEUCINE PEPTIDE RM(PHOSPHOS) EIKRLLSE Q TO E MUTANT
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT SIGMA-1, ...
Authors:Owen, D.J., McCoy, A.J., Kelly, B.T., Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2R51
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CRYSTAL STRUCTURE OF MOUSE VPS26B
Descriptor:Vacuolar protein sorting-associated protein 26B
Authors:Owen, D.J., Teasdale, R.D., Collins, B.M.
Deposit date:2007-09-02
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Vps26B and mapping of its interaction with the retromer protein complex.
Traffic, 9, 2008
2V8S
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VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX
Descriptor:CLATHRIN INTERACTOR 1, VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B, GLYCEROL
Authors:Owen, D.J., McCoy, A.J., Collins, B.M., Miller, S.E.
Deposit date:2007-08-14
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:A Snare-Adaptor Interaction is a New Mode of Cargo Recognition in Clathrin Coated Vesicles
Nature, 450, 2007
2VGL
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AP2 CLATHRIN ADAPTOR CORE
Descriptor:ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
Authors:Owen, D.J., Collins, B.M., McCoy, A.J., Evans, P.R.
Deposit date:2007-11-14
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
5FPI
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MU2 ADAPTIN SUBUNIT OF THE AP2 ADAPTOR (C-TERMINAL DOMAIN) COMPLEXED WITH INTEGRIN ALPHA4 INTERNALISATION PEPTIDE QYKSILQE
Descriptor:AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT
Authors:Owen, D.J., Evans, P.R., Ivaska, J.
Deposit date:2015-11-30
Release date:2016-01-20
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23, 2016
1QL6
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THE CATALYTIC MECHANISM OF PHOSPHORYLASE KINASE PROBED BY MUTATIONAL STUDIES
Descriptor:PHOSPHORYLASE KINASE, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Skamnaki, V.T., Owen, D.J., Noble, M.E.M., Lowe, E.D., Oikonomakos, N.G., Johnson, L.N.
Deposit date:1999-08-24
Release date:1999-12-14
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catalytic Mechanism of Phosphorylase Kinase Probed by Mutational Studies.
Biochemistry, 38, 1999
2PHK
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THE CRYSTAL STRUCTURE OF A PHOSPHORYLASE KINASE PEPTIDE SUBSTRATE COMPLEX: KINASE SUBSTRATE RECOGNITION
Descriptor:PHOSPHORYLASE KINASE, MC-PEPTIDE, MANGANESE (II) ION, ...
Authors:Lowe, E.D., Noble, M.E.M., Skamnaki, V.T., Oikonomakos, N.G., Owen, D.J., Johnson, L.N.
Deposit date:1998-06-18
Release date:1999-01-13
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.
EMBO J., 16, 1997
1GYU
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GAMMA-ADAPTIN APPENDAGE DOMAIN FROM CLATHRIN ADAPTOR AP1
Descriptor:ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT
Authors:Evans, P.R., Owen, D.J., McMahon, H.M., Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Gamma-Adaptin Appendage Domain. Structure and Binding Site for Eps15 and Gamma-Synergin
Structure, 10, 2002
1GYV
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GAMMA-ADAPTIN APPENDAGE DOMAIN FROM CLATHRIN ADAPTOR AP1, L762E MUTANT
Descriptor:ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT
Authors:Evans, P.R., Owen, D.J., McMahon, H.M., Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.
Structure, 10, 2002
1GYW
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GAMMA-ADAPTIN APPENDAGE DOMAIN FROM CLATHRIN ADAPTOR AP1 A753D MUTANT
Descriptor:ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, CHLORIDE ION
Authors:Evans, P.R., Miele, A.E., Owen, D.J., McMahon, H.M., Kent, H.M.
Deposit date:2002-04-30
Release date:2002-08-22
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin.
Structure, 10, 2002
1NA8
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CRYSTAL STRUCTURE OF ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA1
Descriptor:ADP-ribosylation factor binding protein GGA1
Authors:Lui, W.W., Collins, B.M., Hirst, J., Motley, A., Millar, C., Schu, P., Owen, D.J., Robinson, M.S.
Deposit date:2002-11-27
Release date:2003-07-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin
Mol.Cell.Biol., 14, 2003
1NAF
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CRYSTAL STRUCTURE OF THE HUMAN GGA1 GAT DOMAIN
Descriptor:ADP-ribosylation factor binding protein GGA1
Authors:Collins, B.M., Watson, P.J., Owen, D.J.
Deposit date:2002-11-27
Release date:2003-03-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the GGA1-GAT Domain Reveals the Molecular Basis for ARF Binding and Membrane Association of GGAs
Dev.Cell, 4, 2003
1OM9
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STRUCTURE OF THE GGA1-APPENDAGE IN COMPLEX WITH THE P56 BINDING PEPTIDE
Descriptor:ADP-ribosylation factor binding protein GGA1, 15-mer peptide fragment of p56
Authors:Collins, B.M., Praefcke, G.J.K., Robinson, M.S., Owen, D.J.
Deposit date:2003-02-25
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for binding of accessory proteins by the appendage domain of GGAs
Nat.Struct.Biol., 10, 2003
1R4X
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CRYSTAL STRUCTURE ANALYS OF THE GAMMA-COPI APPENDAGE DOMAIN
Descriptor:Coatomer gamma subunit, MAGNESIUM ION
Authors:Watson, P.J., Frigerio, G., Collins, B.M., Duden, R., Owen, D.J.
Deposit date:2003-10-09
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
1UTC
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CLATHRIN TERMINAL DOMAIN COMPLEXED WITH TLPWDLWTT
Descriptor:CLATHRIN HEAVY CHAIN, AMPHIPHYSIN
Authors:Miele, A.E., Evans, P.R., Owen, D.J.
Deposit date:2003-12-08
Release date:2004-02-25
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
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