Author results

5O41
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LOW-DOSE FIXED TARGET SERIAL SYNCHROTRON CRYSTALLOGRAPHY STRUCTURE OF SPERM WHALE MYOGLOBIN
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Owen, R.L., Axford, D., Sherrell, D., Mueller-Werkmeister, H.
Deposit date:2017-05-25
Release date:2017-06-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Low-dose fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 73, 2017
5M3S
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LOW-DOSE FIXED TARGET SERIAL SYNCHROTRON CRYSTALLOGRAPHY STRUCTURE OF METMYOGLOBIN
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Axford, D., Owen, R.L., Sherrell, D., Muller-Werkmeister, H.
Deposit date:2016-10-17
Release date:2016-12-14
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Low-dose fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 73, 2017
4N6T
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ADHIRON: A STABLE AND VERSATILE PEPTIDE DISPLAY SCAFFOLD - FULL LENGTH ADHIRON
Descriptor:Adhiron
Authors:Mcpherson, M., Tomlinson, D., Owen, R.L., Nettleship, J.E., Owens, R.J.
Deposit date:2013-10-14
Release date:2014-04-09
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.
Protein Eng.Des.Sel., 27, 2014
4N6U
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ADHIRON: A STABLE AND VERSATILE PEPTIDE DISPLAY SCAFFOLD - TRUNCATED ADHIRON
Descriptor:Adhiron
Authors:Mcpherson, M., Tomlinson, D., Owen, R.L., Nettleship, J.E., Owens, R.J.
Deposit date:2013-10-14
Release date:2014-04-09
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.
Protein Eng.Des.Sel., 27, 2014
5ML9
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COCRYSTAL STRUCTURE OF FC GAMMA RECEPTOR IIIA INTERACTING WITH AFFIMER F4, A SPECIFIC BINDING PROTEIN WHICH BLOCKS IGG BINDING TO THE RECEPTOR.
Descriptor:Low affinity immunoglobulin gamma Fc region receptor III-A, Affimer F4 with specificity for Fc gamma receptor IIIa, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Robinson, J.I., Tomlinson, D.C., Baxter, E.W., Owen, R.L., Thomsen, M., Win, S.J., Nettleship, J.E., Tiede, C., Foster, R.J., Waterhouse, M.P., Harris, S.A., Owens, R.J., Fishwick, C.W.G., Goldman, A., McPherson, M.J., Morgan, A.W.
Deposit date:2016-12-06
Release date:2017-12-13
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5MN2
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COCRYSTAL STRUCTURE OF FC GAMMA RECEPTOR IIIA INTERACTING WITH AFFIMER G3, A SPECIFIC BINDING PROTEIN WHICH BLOCKS IGG BINDING TO THE RECEPTOR.
Descriptor:Low affinity immunoglobulin gamma Fc region receptor III-A, Affimer G3, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Robinson, J.I., Owen, R.L., Tomlinson, D.C., Baxter, E.W., Nettleship, J.E., Waterhouse, M.P., Harris, S.A., Owens, R.J., McPherson, M.J., Morgan, A.W., Tiede, C., Goldman, A., Thomsen, M.
Deposit date:2016-12-12
Release date:2017-12-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HAL
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HUMAN CARBONMONOXY HEMOGLOBIN SFX DATASET
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Doak, B., Gorel, A., Foucar, L., Barends, T.R.M., Gruenbein, M.L., Hilpert, M., Kloos, M., Nass Kovacs, G., Roome, C.M., Shoeman, R.L., Stricker, M., Tono, K., You, D., Ueda, K., Sherrell, D.A., Owen, R.L., Schlichting, I.
Deposit date:2018-08-07
Release date:2018-10-17
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallography on a chip - without the chip: sheet-on-sheet sandwich.
Acta Crystallogr D Struct Biol, 74, 2018
2WUG
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CRYSTAL STRUCTURE OF S114A MUTANT OF HSAD FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH HOPDA
Descriptor:2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD, (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE, THIOCYANATE ION, ...
Authors:Lack, N.A., Yam, K.C., Lowe, E.D., Horsman, G.P., Owen, R.L., Sim, E., Eltis, L.D.
Deposit date:2009-10-02
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of a C-C Hydrolase from Mycobacterium Tuberuclosis Involved in Cholesterol Metabolism.
J.Biol.Chem., 285, 2010
3E9J
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STRUCTURE OF THE CHARGE-TRANSFER INTERMEDIATE OF THE TRANSMEMBRANE REDOX CATALYST DSBB
Descriptor:Thiol/disulfide oxidoreductase DsbA, Thiol/disulfide oxidoreductase DsbB, UBIQUINONE-1
Authors:Malojcic, G., Owen, R.L., Glockshuber, R.
Deposit date:2008-08-22
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Preparation and structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB.
Febs Lett., 582, 2008
3ELQ
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CRYSTAL STRUCTURE OF A BACTERIAL ARYLSULFATE SULFOTRANSFERASE
Descriptor:Arylsulfate sulfotransferase, SULFATE ION, CHLORIDE ION
Authors:Malojcic, G., Owen, R.L., Grimshaw, J.P., Glockshuber, R.
Deposit date:2008-09-23
Release date:2008-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 105, 2008
3ETS
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CRYSTAL STRUCTURE OF A BACTERIAL ARYLSULFATE SULFOTRANSFERASE CATALYTIC INTERMEDIATE WITH 4-METHYLUMBELLIFERONE BOUND IN THE ACTIVE SITE
Descriptor:Arylsulfate sulfotransferase, 7-hydroxy-4-methyl-2H-chromen-2-one, SULFATE ION
Authors:Malojcic, G., Owen, R.L., Grimshaw, J.P., Glockshuber, R.
Deposit date:2008-10-08
Release date:2008-11-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 105, 2008
3ETT
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CRYSTAL STRUCTURE OF A BACTERIAL ARYLSULFATE SULFOTRANSFERASE CATALYTIC INTERMEDIATE WITH 4-NITROPHENOL BOUND IN THE ACTIVE SITE
Descriptor:Arylsulfate sulfotransferase, P-NITROPHENOL, SULFATE ION
Authors:Malojcic, G., Owen, R.L., Grimshaw, J.P., Glockshuber, R.
Deposit date:2008-10-08
Release date:2008-11-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 105, 2008
4C3C
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THAUMATIN REFINED AGAINST HATRX DATA FOR TIME-POINT 1
Descriptor:THAUMATIN-1, L(+)-TARTARIC ACID
Authors:Yorke, B.A., Beddard, G.S., Owen, R.L., Pearson, A.R.
Deposit date:2013-08-22
Release date:2014-09-03
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Time-Resolved Crystallography Using the Hadamard Transform.
Nat.Methods, 11, 2014
4CIZ
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE CELLULAR RETINAL BINDING PROTEIN WITH 9-CIS-RETINAL
Descriptor:RETINALDEHYDE-BINDING PROTEIN 1, RETINAL, L(+)-TARTARIC ACID
Authors:Bolze, C.S., Helbling, R.E., Owen, R.L., Pearson, A.R., Pompidor, G., Dworkowski, F., Fuchs, M.R., Furrer, J., Golczak, M., Palczewski, K., Cascella, M., Stocker, A.
Deposit date:2013-12-18
Release date:2014-01-08
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (3.403 Å)
Cite:Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
4CJ6
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE CELLULAR RETINAL BINDING PROTEIN MUTANT R234W WITH 9-CIS-RETINAL
Descriptor:RETINALDEHYDE-BINDING PROTEIN 1, RETINAL
Authors:Bolze, C.S., Helbling, R.E., Owen, R.L., Pearson, A.R., Pompidor, G., Dworkowski, F., Fuchs, M.R., Furrer, J., Golczak, M., Palczewski, K., Cascella, M., Stocker, A.
Deposit date:2013-12-19
Release date:2014-01-08
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity.
J.Am.Chem.Soc., 136, 2014
4M8G
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CRYSTAL STRUCTURE OF SE-MET HN33/TUSC3
Descriptor:Tumor suppressor candidate 3
Authors:Mohorko, E., Owen, R.L., Malojcic, G., Brozzo, M.S., Aebi, M., Glockshuber, R.
Deposit date:2013-08-13
Release date:2014-03-26
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
4M90
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CRYSTAL STRUCTURE OF OXIDIZED HN33/TUSC3
Descriptor:Tumor suppressor candidate 3
Authors:Mohorko, E., Owen, R.L., Malojcic, G., Brozzo, M.S., Aebi, M., Glockshuber, R.
Deposit date:2013-08-14
Release date:2014-03-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
4M91
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CRYSTAL STRUCTURE OF HN33/TUSC3-PEPTIDE 1
Descriptor:Tumor suppressor candidate 3, Protein cereblon
Authors:Mohorko, E., Owen, R.L., Malojcic, G., Brozzo, M.S., Aebi, M., Glockshuber, R.
Deposit date:2013-08-14
Release date:2014-03-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
4M92
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CRYSTAL STRUCTURE OF HN33/TUSC3-PEPTIDE 2
Descriptor:Tumor suppressor candidate 3, Interleukin-1 receptor accessory protein-like 1
Authors:Mohorko, E., Owen, R.L., Malojcic, G., Brozzo, M.S., Aebi, M., Glockshuber, R.
Deposit date:2013-08-14
Release date:2014-03-26
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
4P04
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APO FORM OF BACTERIAL ARYLSULFATE SULFOTRANSFERASE (ASST) H436N MUTANT WITH MPO IN THE ACTIVE SITE
Descriptor:Arylsulfate sulfotransferase AssT, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION
Authors:Malojcic, G., Owen, R.L., Glockshuber, R.
Deposit date:2014-02-20
Release date:2014-03-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and mechanistic insights into the PAPS-independent sulfotransfer catalyzed by bacterial aryl sulfotransferase and the role of the DsbL/Dsbl system in its folding.
Biochemistry, 53, 2014
4P05
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BACTERIAL ARYLSULFATE SULFOTRANSFERASE (ASST) H436N MUTANT WITH 4-NITROPHENYL SULFATE (PNS) IN THE ACTIVE SITE
Descriptor:Arylsulfate sulfotransferase AssT, 4-nitrophenyl sulfate, SULFATE ION
Authors:Malojcic, G., Owen, R.L., Glockshuber, R.
Deposit date:2014-02-20
Release date:2014-03-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and mechanistic insights into the PAPS-independent sulfotransfer catalyzed by bacterial aryl sulfotransferase and the role of the DsbL/Dsbl system in its folding.
Biochemistry, 53, 2014
4P06
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BACTERIAL ARYLSULFATE SULFOTRANSFERASE (ASST) H436N MUTANT WITH 4-METHYLUMBELLIFERYL SULFATE (MUS) IN THE ACTIVE SITE
Descriptor:Arylsulfate sulfotransferase AssT, SULFATE ION, (4-methyl-2-oxidanylidene-chromen-7-yl) hydrogen sulfate
Authors:Malojcic, G., Owen, R.L., Glockshuber, R.
Deposit date:2014-02-20
Release date:2014-03-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and mechanistic insights into the PAPS-independent sulfotransfer catalyzed by bacterial aryl sulfotransferase and the role of the DsbL/Dsbl system in its folding.
Biochemistry, 53, 2014
4P07
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BACTERIAL ARYL SULFOTRANSFERASE (ASST) SOAKED WITH HUMAN URINE
Descriptor:Arylsulfate sulfotransferase AssT, SULFATE ION
Authors:Malojcic, G., Owen, R.L., Glockshuber, R.
Deposit date:2014-02-20
Release date:2014-03-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural and mechanistic insights into the PAPS-independent sulfotransfer catalyzed by bacterial aryl sulfotransferase and the role of the DsbL/Dsbl system in its folding.
Biochemistry, 53, 2014
5JOM
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X-RAY STRUCTURE OF CO-BOUND SPERM WHALE MYOGLOBIN USING A FIXED TARGET CRYSTALLOGRAPHY CHIP
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Oghbaey, S., Sarracini, A., Ginn, H.M., Pare-Labrosse, O., Kuo, A., Marx, A., Epp, S.W., Sherrell, D.A., Eger, B.T., Zhong, Y., Loch, R., Mariani, V., Alonso-Mori, R., Nelson, S., Lemke, H.T., Owen, R.L., Pearson, A.R., Stuart, D.I., Ernst, O.P., Mueller-Werkmeister, H.M., Miller, R.J.D.
Deposit date:2016-05-02
Release date:2016-08-17
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fixed target combined with spectral mapping: approaching 100% hit rates for serial crystallography.
Acta Crystallogr D Struct Biol, 72, 2016
6GB8
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COPPER NITRITE REDUCTASE FROM ACHROMOBACTER CYCLOCLASTES: SMALL CELL POLYMORPH DATASET 1
Descriptor:Copper-containing nitrite reductase, COPPER (II) ION, NITRITE ION
Authors:Ebrahim, A., Appleby, M.V., Axford, D., Beale, J., Moreno-Chicano, T., Sherrell, D.A., Strange, R.W., Owen, R.L., Hough, M.A.
Deposit date:2018-04-13
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 75, 2019