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1A0A
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PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX
Descriptor:DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4)
Authors:Shimizu, T., Toumoto, A., Ihara, K., Shimizu, M., Kyogoku, Y., Ogawa, N., Oshima, Y., Hakoshima, T.
Deposit date:1997-11-27
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997
3WJ1
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CRYSTAL STRUCTURE OF SSHESTI
Descriptor:Carboxylesterase, B-OCTYLGLUCOSIDE
Authors:Ohara, K., Unno, H., Oshima, Y., Furukawa, K., Fujino, N., Hirooka, K., Hemmi, H., Takahashi, S., Nishino, T., Kusunoki, M., Nakayama, T.
Deposit date:2013-10-03
Release date:2014-07-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insights into the Low-pH Adaptation of a Unique Carboxylesterase from Ferroplasma: Altering the pH Optima of Two Carboxylesterases
J.Biol.Chem., 2014
3WJ2
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CRYSTAL STRUCTURE OF ESTFA (FE-LACKING APO FORM)
Descriptor:Carboxylesterase
Authors:Ohara, K., Unno, H., Oshima, Y., Furukawa, K., Fujino, N., Hirooka, K., Hemmi, H., Takahashi, S., Nishino, T., Kusunoki, M., Nakayama, T.
Deposit date:2013-10-03
Release date:2014-07-30
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural Insights into the Low-pH Adaptation of a Unique Carboxylesterase from Ferroplasma: Altering the pH Optima of Two Carboxylesterases
J.Biol.Chem., 2014
5XIF
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CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE (PRS) FROM TOXOPLASMA GONDII
Descriptor:Prolyl-tRNA synthetase (ProRS), CHLORIDE ION
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIG
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROLYL-TRNA SYNTHETASE (TGPRS) IN COMPLEX WITH INHIBITOR 1
Descriptor:Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIH
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROLYL-TRNA SYNTHETASE (TGPRS) IN COMPLEX WITH INHIBITOR 5
Descriptor:Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XII
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROLYL-TRNA SYNTHETASE (TGPRS) IN COMPLEX WITH INHIBITOR 6
Descriptor:Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIJ
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROLYL-TRNA SYNTHETASE (TGPRS) IN COMPLEX WITH INHIBITOR 9
Descriptor:Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIK
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROLYL-TRNA SYNTHETASE (TGPRS) IN COMPLEX WITH TETRAHYDRO QUINAZOLINONE FEBRIFUGINE
Descriptor:Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIL
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CRYSTAL STRUCTURE OF LEISHMANIA MAJOR PROLYL-TRNA SYNTHETASE (LMPRS)
Descriptor:Putative prolyl-tRNA synthetase, ZINC ION, ACETATE ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIO
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CRYSTAL STRUCTURE OF CRYPTOSPORIDIUM PARVUM PROLYL-TRNA SYNTHETASE (CPPRS) IN COMPLEX WITH HALOFUGINONE
Descriptor:Proline-tRNA synthetase class II aaRS (Ybak RNA binding domain plus tRNA synthetase), 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ZINC ION, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIP
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CRYSTAL STRUCTURE OF EIMERIA TENELLA PROLYL-TRNA SYNTHETASE (ETPRS) IN COMPLEX WITH HALOFUGINONE
Descriptor:Prolyl-tRNA synthetase, putative, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIQ
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CRYSTAL STRUCTURE OF TOXOPLASMA GONDII PROLYL-TRNA SYNTHETASE (TGPRS) IN COMPLEX WITH HALOFUGINONE
Descriptor:Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ...
Authors:Jain, V., Manickam, Y., Sharma, A.
Deposit date:2017-04-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
2CB3
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CRYSTAL STRUCTURE OF PEPTIDOGLYCAN RECOGNITION PROTEIN-LE IN COMPLEX WITH TRACHEAL CYTOTOXIN (MONOMERIC DIAMINOPIMELIC ACID-TYPE PEPTIDOGLYCAN)
Descriptor:PEPTIDOGLYCAN-RECOGNITION PROTEIN-LE, GLYCEROL, GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA
Authors:Lim, J.-H., Kim, M.-S., Oh, B.-H.
Deposit date:2005-12-29
Release date:2006-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Preferential Recognition of Diaminopimelic Acid-Type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins
J.Biol.Chem., 281, 2006
4P9N
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CRYSTAL STRUCTURE OF SSHESTI PE MUTANT
Descriptor:Carboxylesterase
Authors:Unno, H.
Deposit date:2014-04-04
Release date:2014-07-30
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insights into the Low pH Adaptation of a Unique Carboxylesterase from Ferroplasma: ALTERING THE pH OPTIMA OF TWO CARBOXYLESTERASES.
J.Biol.Chem., 289, 2014
4TWA
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CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE (PRS) FROM PLASMODIUM FALCIPARUM
Descriptor:Proline--tRNA ligase, CHLORIDE ION, SULFATE ION
Authors:Jain, V., Yogavel, M., Sharma, A.
Deposit date:2014-06-30
Release date:2014-08-13
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase.
J. Struct. Funct. Genomics, 15, 2014
4YDQ
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CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE (PRS) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH HALOFUGINONE AND AMPPNP
Descriptor:Proline--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ...
Authors:Jain, V., Yogavel, M., Sharma, A.
Deposit date:2015-02-23
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis
Structure, 23, 2015