Author results

5LTE
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CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HEME DEPENDENT OXIDATIVE N-DEMETHYLASE (HODM)
Descriptor:heme dependent oxidative N-demethylase, PROTOPORPHYRIN IX CONTAINING FE, 2-ETHOXYETHANOL, ...
Authors:Ortmayer, M., Leys, D.
Deposit date:2016-09-06
Release date:2016-11-09
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
5LTH
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CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HEME DEPENDENT OXIDATIVE N-DEMETHYLASE (HODM) IN COMPLEX WITH THE DIMETHYLAMINE SUBSTRATE
Descriptor:heme dependent oxidative N-demethylase, PROTOPORPHYRIN IX CONTAINING FE, DIMETHYLAMINE, ...
Authors:Ortmayer, M., Leys, D.
Deposit date:2016-09-06
Release date:2016-11-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
5LTI
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CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HEME DEPENDENT OXIDATIVE N-DEMETHYLASE (HODM) IN COMPLEX WITH THE DIMETHYLAMINE SUBSTRATE
Descriptor:heme dependent oxidative N-demethylase, PROTOPORPHYRIN IX CONTAINING FE, DIMETHYLAMINE, ...
Authors:Ortmayer, M., Leys, D.
Deposit date:2016-09-06
Release date:2016-11-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
6H08
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THE CRYSTAL STRUCTURE OF ENGINEERED CYTOCHROME C PEROXIDASE FROM SACCHAROMYCES CEREVISIAE WITH A HIS175ME-HIS PROXIMAL LIGAND SUBSTITUTION
Descriptor:Cytochrome c peroxidase, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ortmayer, M., Levy, C., Green, A.P.
Deposit date:2018-07-06
Release date:2020-02-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rewiring the Push-Pull Catalytic Machinery of a Haem Enzyme using an Expanded Genetic Code
To Be Published
5A35
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CRYSTAL STRUCTURE OF GLYCINE CLEAVAGE PROTEIN H-LIKE (GCVH-L) FROM STREPTOCOCCUS PYOGENES
Descriptor:GLYCINE CLEAVAGE SYSTEM H PROTEIN, PENTAETHYLENE GLYCOL
Authors:Rack, J.G.M., Morra, R., Barkauskaite, E., Kraehenbuehl, R., Ariza, A., Qu, Y., Ortmayer, M., Leidecker, O., Cameron, D.R., Matic, I., Peleg, A.Y., Leys, D., Traven, A., Ahel, I.
Deposit date:2015-05-27
Release date:2015-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
5A3A
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CRYSTAL STRUCTURE OF THE ADP-RIBOSYLATING SIRTUIN (SIRTM) FROM STREPTOCOCCUS PYOGENES (APO FORM)
Descriptor:SIR2 FAMILY PROTEIN, GLYCINE, ZINC ION, ...
Authors:Rack, J.G.M., Morra, R., Barkauskaite, E., Kraehenbuehl, R., Ariza, A., Qu, Y., Ortmayer, M., Leidecker, O., Cameron, D.R., Matic, I., Peleg, A.Y., Leys, D., Traven, A., Ahel, I.
Deposit date:2015-05-28
Release date:2015-07-29
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
5A3B
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CRYSTAL STRUCTURE OF THE ADP-RIBOSYLATING SIRTUIN (SIRTM) FROM STREPTOCOCCUS PYOGENES IN COMPLEX WITH ADP-RIBOSE
Descriptor:SIR2 FAMILY PROTEIN, GLYCINE, ALANINE, ...
Authors:Rack, J.G.M., Morra, R., Barkauskaite, E., Kraehenbuehl, R., Ariza, A., Qu, Y., Ortmayer, M., Leidecker, O., Cameron, D.R., Matic, I., Peleg, A.Y., Leys, D., Traven, A., Ahel, I.
Deposit date:2015-05-28
Release date:2015-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
5A3C
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CRYSTAL STRUCTURE OF THE ADP-RIBOSYLATING SIRTUIN (SIRTM) FROM STREPTOCOCCUS PYOGENES IN COMPLEX WITH NAD
Descriptor:SIR2 FAMILY PROTEIN, GLYCINE, ZINC ION, ...
Authors:Rack, J.G.M., Morra, R., Barkauskaite, E., Kraehenbuehl, R., Ariza, A., Qu, Y., Ortmayer, M., Leidecker, O., Cameron, D.R., Matic, I., Peleg, A.Y., Leys, D., Traven, A., Ahel, I.
Deposit date:2015-05-28
Release date:2015-07-29
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens.
Mol.Cell, 59, 2015
6Q7N
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CRYSTAL STRUCTURE OF BH32 ALKYLATED WITH THE MECHANISTIC INHIBITOR 2-BROMOACETOPHENONE
Descriptor:BH32, 1-PHENYLETHANONE
Authors:Levy, C.W.
Deposit date:2018-12-13
Release date:2019-06-05
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7O
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CRYSTAL STRUCTURE OF OE1
Descriptor:OE1, CALCIUM ION
Authors:Levy, C.W.
Deposit date:2018-12-13
Release date:2019-06-05
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7P
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CRYSTAL STRUCTURE OF OE1.2
Descriptor:OE1.2, TRIETHYLENE GLYCOL, 1-PHENYLETHANONE, ...
Authors:Levy, C.W.
Deposit date:2018-12-13
Release date:2019-06-05
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7Q
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CRYSTAL STRUCTURE OF OE1.3
Descriptor:OE1.3
Authors:Levy, C.W.
Deposit date:2018-12-13
Release date:2019-06-05
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019
6Q7R
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CRYSTAL STRUCTURE OF OE1.3 ALKYLATED WITH THE MECHANISTIC INHIBITOR 2-BROMOACETOPHENONE
Descriptor:OE1.3, 1-PHENYLETHANONE, ACETATE ION, ...
Authors:Levy, C.W.
Deposit date:2018-12-13
Release date:2019-06-05
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.
Nature, 570, 2019