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4AQH
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BU of 4aqh by Molmil
Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976
Descriptor: PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE
Authors:Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D.
Deposit date:2012-04-17
Release date:2012-11-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation
J.Biol.Chem., 288, 2013
4A5T
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BU of 4a5t by Molmil
STRUCTURAL BASIS FOR THE CONFORMATIONAL MODULATION
Descriptor: CHLORIDE ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, PLASMINOGEN
Authors:Xue, Y, Bodin, C, Olsson, K.
Deposit date:2011-10-28
Release date:2012-05-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Crystal Structure of the Native Plasminogen Reveals an Activation-Resistant Compact Conformation.
J. Thromb. Haemost., 10, 2012

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