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1PKW
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1 IN COMPLEX WITH GLUTATHIONE
Descriptor:Glutathione S-transferase A1, GLUTATHIONE, 2-HYDROXYETHYL DISULFIDE
Authors:Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
Deposit date:2003-06-06
Release date:2004-06-22
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PKZ
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1
Descriptor:Glutathione S-transferase A1, 2-HYDROXYETHYL DISULFIDE
Authors:Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
Deposit date:2003-06-06
Release date:2004-06-22
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PL1
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1 IN COMPLEX WITH A DECARBOXY-GLUTATHIONE
Descriptor:Glutathione S-transferase A1, CHLORIDE ION, N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE
Authors:Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
Deposit date:2003-06-06
Release date:2004-06-22
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1PL2
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CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE (GST) A1-1 T68E MUTANT IN COMPLEX WITH DECARBOXY-GLUTATHIONE
Descriptor:Glutathione S-transferase A1, CHLORIDE ION, N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE
Authors:Grahn, E., Jakobsson, E., Gustafsson, A., Grehn, L., Olin, B., Wahlberg, M., Madsen, D., Kleywegt, G.J., Mannervik, B.
Deposit date:2003-06-06
Release date:2004-06-22
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1QH3
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HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE
Descriptor:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, CACODYLATE ION, ...
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-05-10
Release date:1999-09-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1QH5
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HUMAN GLYOXALASE II WITH S-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONE
Descriptor:PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), ZINC ION, GLUTATHIONE, ...
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-05-11
Release date:1999-09-24
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1QIN
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HUMAN GLYOXALASE I COMPLEXED WITH S-(N-HYDROXY-N-P-IODOPHENYLCARBAMOYL) GLUTATHIONE
Descriptor:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-(N-HYDROXY-N-IODOPHENYLCARBAMOYL)GLUTATHIONE
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-06-14
Release date:1999-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1QIP
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HUMAN GLYOXALASE I COMPLEXED WITH S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE
Descriptor:PROTEIN (LACTOYLGLUTATHIONE LYASE), ZINC ION, S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE, ...
Authors:Cameron, A.D., Ridderstrom, M., Olin, B., Mannervik, B.
Deposit date:1999-06-14
Release date:1999-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1XWG
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HUMAN GST A1-1 T68E MUTANT
Descriptor:Glutathione S-transferase A1
Authors:Grahn, E., Jakobsson, E., Gustafsson, A., Novotny, M., Grehn, L., Olin, B., Madsen, D., Wahlberg, M., Mannervik, B., Kleywegt, G.J.
Deposit date:2004-11-01
Release date:2005-11-01
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
2C3N
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HUMAN GLUTATHIONE-S-TRANSFERASE T1-1, APO FORM
Descriptor:GLUTATHIONE S-TRANSFERASE THETA 1, IODIDE ION
Authors:Tars, K., Larsson, A.-K., Shokeer, A., Olin, B., Mannervik, B., Kleywegt, G.J.
Deposit date:2005-10-11
Release date:2005-11-30
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3Q
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HUMAN GLUTATHIONE-S-TRANSFERASE T1-1 W234R MUTANT, COMPLEX WITH S- HEXYLGLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE THETA 1, S-HEXYLGLUTATHIONE, IODIDE ION
Authors:Tars, K., Larsson, A.-K., Shokeer, A., Olin, B., Mannervik, B., Kleywegt, G.J.
Deposit date:2005-10-11
Release date:2005-11-30
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3T
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HUMAN GLUTATHIONE-S-TRANSFERASE T1-1, W234R MUTANT, APO FORM
Descriptor:GLUTATHIONE S-TRANSFERASE THETA 1
Authors:Tars, K., Larsson, A.-K., Shokeer, A., Olin, B., Mannervik, B., Kleywegt, G.J.
Deposit date:2005-10-12
Release date:2005-11-30
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2VCT
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GLUTATHIONE TRANSFERASE A2-2 IN COMPLEX WITH DELTA-4-ANDOSTRENE-3-17- DIONE
Descriptor:GLUTATHIONE S-TRANSFERASE A2, 4-ANDROSTENE-3-17-DIONE
Authors:Tars, K., Olin, B., Mannervik, B.
Deposit date:2007-09-27
Release date:2008-10-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2VCV
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GLUTATHIONE TRANSFERASE A3-3 IN COMPLEX WITH GLUTATHIONE AND DELTA-4- ANDROSTENE-3-17-DIONE
Descriptor:GLUTATHIONE S-TRANSFERASE A3, GLUTATHIONE, 4-ANDROSTENE-3-17-DIONE
Authors:Tars, K., Olin, B., Mannervik, B.
Deposit date:2007-09-27
Release date:2008-10-28
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
2WJU
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GLUTATHIONE TRANSFERASE A2-2 IN COMPLEX WITH GLUTATHIONE
Descriptor:GLUTATHIONE-S-TRANSFERASE A2-2, GLUTATHIONE
Authors:Tars, K., Olin, B., Mannervik, B.
Deposit date:2009-05-29
Release date:2009-06-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases.
J.Mol.Biol., 397, 2010
1GSD
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GLUTATHIONE TRANSFERASE A1-1 IN UNLIGANDED FORM
Descriptor:GLUTATHIONE TRANSFERASE A1-1
Authors:L'Hermite, G., Sinning, I., Cameron, A.D., Jones, T.A.
Deposit date:1995-06-09
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
1GSE
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GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH AN ETHACRYNIC ACID GLUTATHIONE CONJUGATE (MUTANT R15K)
Descriptor:GLUTATHIONE TRANSFERASE, GLUTATHIONE, ETHACRYNIC ACID, ...
Authors:Cameron, A.D., Jones, T.A.
Deposit date:1995-06-09
Release date:1995-09-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
1GSF
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GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH ETHACRYNIC ACID
Descriptor:GLUTATHIONE TRANSFERASE A1-1, ETHACRYNIC ACID
Authors:L'Hermite, G., Sinning, I., Cameron, A.D., Jones, T.A.
Deposit date:1995-06-09
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
2C4J
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HUMAN GLUTATHIONE-S-TRANSFERASE M2-2 T210S MUTANT IN COMPLEX WITH GLUTATHIONE-STYRENE OXIDE CONJUGATE
Descriptor:GLUTATHIONE S-TRANSFERASE MU 2, L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE
Authors:Tars, K., Andersson, M., Ivarsson, Y., Olin, B., Mannervik, B.
Deposit date:2005-10-20
Release date:2005-10-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Alternative Mutations of a Positively Selected Residue Elicit Gain or Loss of Functionalities in Enzyme Evolution.
Proc.Natl.Acad.Sci.USA, 103, 2006
1FRO
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HUMAN GLYOXALASE I WITH BENZYL-GLUTATHIONE INHIBITOR
Descriptor:LACTOYLGLUTATHIONE LYASE, ZINC ION, S-BENZYL-GLUTATHIONE
Authors:Cameron, A.D., Jones, T.A.
Deposit date:1997-02-25
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping.
EMBO J., 16, 1997
1GUH
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STRUCTURE DETERMINATION AND REFINEMENT OF HUMAN ALPHA CLASS GLUTATHIONE TRANSFERASE A1-1, AND A COMPARISON WITH THE MU AND PI CLASS ENZYMES
Descriptor:GLUTATHIONE S-TRANSFERASE A1-1, S-BENZYL-GLUTATHIONE
Authors:Sinning, I., Kleywegt, G.J., Jones, T.A.
Deposit date:1993-02-24
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.
J.Mol.Biol., 232, 1993
1GNE
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THE THREE-DIMENSIONAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE OF SCHISTOSOMA JAPONICUM FUSED WITH A CONSERVED NEUTRALIZING EPITOPE ON GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE
Authors:Lim, K., Ho, J.X., Keeling, K., Gilliland, G.L., Ji, X., Ruker, F., Carter, D.C.
Deposit date:1994-06-16
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV.
Protein Sci., 3, 1994