Author results

6I59
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LONG WAVELENGTH NATIVE-SAD PHASING OF SEN1 HELICASE
Descriptor:Helicase SEN1, ADENOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
6I5C
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LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
6QBY
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CRYSTAL STRUCTURE OF VASH 2 IN COMPLEX WITH SVBP
Descriptor:Tubulinyl-Tyr carboxypeptidase 2, Small vasohibin-binding protein
Authors:Choi, S.R., Olieric, V., Steinmetz, M.O., Olieric, N.
Deposit date:2018-12-24
Release date:2019-04-24
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.
Nat.Struct.Mol.Biol., 26, 2019
3Q0X
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N-TERMINAL COILED-COIL DIMER DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P
Descriptor:Centriole protein
Authors:Kitagawa, D., Vakonakis, I., Olieric, N., Hilbert, M., Keller, D., Olieric, V., Bortfeld, M., Erat, M.C., Flueckiger, I., Goenczy, P., Steinmetz, M.O.
Deposit date:2010-12-16
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
3Q0Y
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N-TERMINAL DOMAIN OF C. REINHARDTII SAS-6 HOMOLOG BLD12P
Descriptor:Centriole protein
Authors:Kitagawa, D., Vakonakis, I., Olieric, N., Hilbert, M., Keller, D., Olieric, V., Bortfeld, M., Erat, M.C., Flueckiger, I., Goenczy, P., Steinmetz, M.O.
Deposit date:2010-12-16
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
5NR4
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CRYSTAL STRUCTURE OF CLASP2 TOG1 DOMAIN
Descriptor:CLIP-associating protein 2
Authors:Sharma, A., Olieric, N., Weinert, T., Olieric, V., Steinmetz, M.O.
Deposit date:2017-04-21
Release date:2018-05-30
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain.
Dev. Cell, 46, 2018
3O0A
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CRYSTAL STRUCTURE OF THE WILD TYPE CP1 HYDROLITIC DOMAIN FROM AQUIFEX AEOLICUS LEUCYL-TRNA
Descriptor:Leucyl-tRNA synthetase subunit alpha
Authors:Cura, V., Olieric, N., Wang, E.-D., Moras, D., Eriani, G., Cavarelli, J.
Deposit date:2010-07-19
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal Structure of the Wild Type and Two Mutants of the Cp1 Hydrolytic Domain from Aquifex Aeolicus Leucyl-tRNA Synthetase
To be Published
5NM5
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TUBULIN DARPIN ROOM-TEMPERATURE STRUCTURE IN COMPLEX WITH COLCHICINE DETERMINED BY SERIAL MILLISECOND CRYSTALLOGRAPHY
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed Ankyrin Repeat Protein (DARPIN) D1, ...
Authors:Weinert, T., Olieric, N., James, D., Gashi, D., Nogly, P., Jaeger, K., Steinmetz, M.O., Standfuss, J.
Deposit date:2017-04-05
Release date:2017-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
5NQT
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TUBULIN DARPIN ROOM-TEMPERATURE STRUCTURE DETERMINED BY SERIAL MILLISECOND CRYSTALLOGRAPHY
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1, ...
Authors:Weinert, T., Olieric, N., James, D., Gashi, D., Nogly, P., Jaeger, K., Steinmetz, M.O., Standfuss, J.
Deposit date:2017-04-21
Release date:2017-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
5NQU
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TUBULIN DARPIN CRYO STRUCTURE
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed Ankyrin Repeat Protein (DARPIN) D1, ...
Authors:Weinert, T., Olieric, N., James, D., Gashi, D., Nogly, P., Jaeger, K., Steinmetz, M.O., Standfuss, J.
Deposit date:2017-04-21
Release date:2017-09-27
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
5O7A
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QUINOLIN-6-YLOXYACETAMIDES ARE MICROTUBULE DESTABILIZING AGENTS THAT BIND TO THE COLCHICINE SITE OF TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Sharma, A., Olieric, N., Steinmetz, M.O.
Deposit date:2017-06-08
Release date:2017-07-05
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin.
Int J Mol Sci, 18, 2017
6FLJ
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CRYSTAL STRUCTURE OF CEP120 C2A_K76A MUTANT
Descriptor:Centrosomal protein of 120 kDa
Authors:Sharma, A., Gerard, S.F., Olieric, N., Steinmetz, M.O.
Deposit date:2018-01-26
Release date:2018-02-14
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Cep120 promotes microtubule formation through a unique tubulin binding C2 domain.
J. Struct. Biol., 203, 2018
6FLK
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CRYSTAL STRUCTURE OF CEP120 C2C DOMAIN
Descriptor:Cep120
Authors:Sharma, A., Gerard, S.F., Olieric, N., Steinmetz, M.O.
Deposit date:2018-01-26
Release date:2018-02-14
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cep120 promotes microtubule formation through a unique tubulin binding C2 domain.
J. Struct. Biol., 203, 2018
6GF3
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TUBULIN-JERANTININE B ACETATE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Smedley, C.J., Stanley, P.A., Qazzaz, M.E., Prota, A.E., Olieric, N., Collins, H., Eastman, H., Barrow, A.S., Lim, K.-H., Kam, T.-S., Smith, B.J., Duivenvoorden, H.M., Parker, B.S., Bradshaw, T.D., Steinmetz, M.O., Moses, J.E.
Deposit date:2018-04-29
Release date:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site.
Sci Rep, 8, 2018
6GJ4
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TUBULIN-6J COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Brindisi, M., Ulivieri, C., Alfano, G., Gemma, S., Balaguer, F.d.A., Khan, T., Grillo, A., Chemi, G., Menchon, G., Prota, A.E., Olieric, N., Agell, D.L., Barasoain, I., Diaz, J.F., Nebbioso, A., Conte, M.R., Lopresti, L., Magnano, S., Amet, R., Kinsella, P., Zisterer, D.M., Ibrahim, O., O'Sullivan, J., Morbidelli, L., Spaccapelo, R., Baldari, C., Butini, S., Novellino, E., Campiani, G., Altucci, L., Steinmetz, M.O., Brogi, S.
Deposit date:2018-05-16
Release date:2018-12-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
Eur J Med Chem, 162, 2018
5DWK
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DIACYLGLYCEROL KINASE SOLVED BY MULTI CRYSTAL MULTI ORIENTATION NATIVE SAD
Descriptor:Diacylglycerol kinase, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Weinert, T., Olieric, V., Finke, A.D., Li, D., Caffrey, M., Wang, M.
Deposit date:2015-09-22
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Data-collection strategy for challenging native SAD phasing.
Acta Crystallogr D Struct Biol, 72, 2016
5FQ5
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CRYSTAL STRUCTURE OF CAS9-SGRNA-DNA COMPLEX SOLVED BY NATIVE SAD PHASING
Descriptor:SGRNA, CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, TARGET DNA STRAND PROXIMAL FRAGMENT, ...
Authors:Olieric, V., Weinert, T., Finke, A., Anders, C., Jinek, M., Wang, M.
Deposit date:2015-12-07
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.136 Å)
Cite:Data-Collection Strategy for Challenging Native Sad Phasing.
Acta Crystallogr.,Sect.D, 72, 2016
3PYI
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STRUCTURE OF THE N-TERMINAL DOMAIN OF C. ELEGANS SAS-6
Descriptor:Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Vakonakis, I., Steinmetz, M.O.
Deposit date:2010-12-13
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
5FCM
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CRBLD10-N 1-70
Descriptor:Basal body protein, ISOPROPYL ALCOHOL, SULFATE ION
Authors:Kraatz, S.H.W., Steinmetz, M.O.
Deposit date:2015-12-15
Release date:2016-07-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.229 Å)
Cite:The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structure, 24, 2016
5FCN
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MICROTUBULE BINDING DOMAIN OF HUMAN CEP135
Descriptor:Centrosomal protein of 135 kDa
Authors:Kraatz, S.H.W.
Deposit date:2015-12-15
Release date:2016-07-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structure, 24, 2016
5LOV
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DZ-2384 TUBULIN COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Prota, A.E., Steinmetz, M.O., Shore, G.C., Brouhard, G., Roulston, A.
Deposit date:2016-08-10
Release date:2016-11-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Sci Transl Med, 8, 2016
5MUE
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SELF-ASSEMBLED ALPHA-TOCOPHEROL TRANSFER PROTEIN NANOPARTICLES PROMOTE VITAMIN E DELIVERY ACROSS AN ENDOTHELIAL BARRIER
Descriptor:Alpha-tocopherol transfer protein, SULFATE ION, (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, ...
Authors:Stocker, A., Aeschimann, W.
Deposit date:2017-01-13
Release date:2017-07-19
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Self-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier.
Sci Rep, 7, 2017
5MUG
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SELF-ASSEMBLED ALPHA-TOCOPHEROL TRANSFER PROTEIN NANOPARTICLES PROMOTE VITAMIN E DELIVERY ACROSS AN ENDOTHELIAL BARRIER
Descriptor:Alpha-tocopherol transfer protein, (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, SULFATE ION, ...
Authors:Stocker, A., Aeschimann, W.
Deposit date:2017-01-13
Release date:2017-07-19
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Self-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier.
Sci Rep, 7, 2017
5NJH
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TRIAZOLOPYRIMIDINES STABILIZE MICROTUBULES BY BINDING TO THE VINCA INHIBITOR SITE OF TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Sharma, A., Calvo, G.S., Prota, A.E., Diaz, J.F., Steinmetz, M.O.
Deposit date:2017-03-28
Release date:2017-06-21
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Cell Chem Biol, 24, 2017
5NJM
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LYSOZYME ROOM-TEMPERATURE STRUCTURE DETERMINED BY SERIAL MILLISECOND CRYSTALLOGRAPHY
Descriptor:Lysozyme C
Authors:Weinert, T., Vera, L., Marsh, M., James, D., Gashi, D., Nogly, P., Jaeger, K., Standfuss, J.
Deposit date:2017-03-29
Release date:2017-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
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