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1A3G
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BU of 1a3g by Molmil
BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE FROM ESCHERICHIA COLI
Descriptor: BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Okada, K, Hirotsu, K, Sato, M, Hayashi, H, Kagamiyama, H.
Deposit date:1998-01-21
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of Escherichia coli branched-chain amino acid aminotransferase at 2.5 A resolution.
J.Biochem.(Tokyo), 121, 1997
2F87
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BU of 2f87 by Molmil
Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus
Descriptor: SRP RNA
Authors:Okada, K, Takahashi, M, Sakamoto, T, Nakamura, K, Kanai, A, Kawai, G
Deposit date:2005-12-02
Release date:2006-08-08
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus
Nucleosides Nucleotides Nucleic Acids, 25, 2006
3AOW
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BU of 3aow by Molmil
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with AKG
Descriptor: 2-OXOGLUTARIC ACID, PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein PH0207
Authors:Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2010-10-07
Release date:2011-10-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Characterization of kynurenine aminotransferase from hyperthermophilic archaeon: enzymatic activity for conversion to kynurenic acid is allosterically regulated by alpha-ketoglutaric acid cooperatively with kynurenine
To be Published
3AOV
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BU of 3aov by Molmil
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PLP
Descriptor: PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein PH0207
Authors:Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2010-10-07
Release date:2011-10-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Characterization of kynurenine aminotransferase from hyperthermophilic archaeon: enzymatic activity for conversion to kynurenic acid is allosterically regulated by alpha-ketoglutaric acid cooperatively with kynurenine
To be Published
3ATH
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BU of 3ath by Molmil
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with four AKGs as substrates and allosteric effectors
Descriptor: 2-OXOGLUTARIC ACID, PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein PH0207
Authors:Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2011-01-05
Release date:2012-01-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Characterization of kynurenine aminotransferase from hyperthermophilic archaeon: enzymatic activity for conversion to kynurenic acid is allosterically regulated by alpha-ketoglutaric acid cooperatively with kynurenine
To be Published
3AV7
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BU of 3av7 by Molmil
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products
Descriptor: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-hydroxyquinoline-2-carboxylic acid, ...
Authors:Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S.
Deposit date:2011-02-23
Release date:2012-03-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural insight into kynurenic acid excretion mechanisms of kynurenine aminotransferase in the hyperthermophilic archaeon Pyrococcus horikoshii
To be Published
3AW8
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BU of 3aw8 by Molmil
Crystal structure of N5-carboxyaminoimidazole ribonucleotide synthetase from Thermus thermophilus HB8
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Phosphoribosylaminoimidazole carboxylase, ...
Authors:Okada, K, Tsunoda, S, Taka, H, Baba, S, Kanagawa, M, Nakagawa, N, Ebihara, A, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2011-03-15
Release date:2012-04-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of N5-carboxyaminoimidazole ribonucleotide synthetase, PurK, from thermophilic bacteria
To be Published
1I1K
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BU of 1i1k by Molmil
CRYSTAL STRUCTURE OF ESCHELICHIA COLI BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE.
Descriptor: BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Okada, K, Hirotsu, K, Hayashi, H, Kagamiyama, H.
Deposit date:2001-02-02
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
Biochemistry, 40, 2001
1I1L
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BU of 1i1l by Molmil
CRYSTAL STRUCTURE OF ESCHELICHIA COLI BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE.
Descriptor: 2-METHYLLEUCINE, BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Okada, K, Hirotsu, K, Hayashi, H, Kagamiyama, H.
Deposit date:2001-02-02
Release date:2001-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
Biochemistry, 40, 2001
1I1M
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BU of 1i1m by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE.
Descriptor: 4-METHYL VALERIC ACID, BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Okada, K, Hirotsu, K, Hayashi, H, Kagamiyama, H.
Deposit date:2001-02-02
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
Biochemistry, 40, 2001
2Z04
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BU of 2z04 by Molmil
Crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit from Aquifex aeolicus
Descriptor: Phosphoribosylaminoimidazole carboxylase ATPase subunit, SULFATE ION
Authors:Okada, K, Tamura, S, Baba, S, Kanagawa, M, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-06
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit from Aquifex aeolicus
To be Published
3WX9
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BU of 3wx9 by Molmil
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA
Descriptor: (2E)-pent-2-enedioic acid, 2-OXOGLUTARIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ...
Authors:Okada, K, Angkawidjaja, C, Koga, Y, Kanaya, S.
Deposit date:2014-07-28
Release date:2014-09-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA
To be Published
5VAD
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BU of 5vad by Molmil
Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor
Descriptor: 3-[(cyclohexanecarbonyl)amino]-N-(2,3-dihydro-1H-inden-2-yl)pyrazine-2-carboxamide, Bifunctional glutamate/proline--tRNA ligase, PROLINE, ...
Authors:Okada, K, Skene, R.J.
Deposit date:2017-03-24
Release date:2017-05-31
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline.
Biochem. Biophys. Res. Commun., 488, 2017
6JZJ
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BU of 6jzj by Molmil
Structure of FimA type-2 (FimA2) prepilin of the type V major fimbrium
Descriptor: Major fimbrium subunit FimA type-2, SULFATE ION
Authors:Okada, K, Shoji, M, Nakayam, K, Imada, K.
Deposit date:2019-05-02
Release date:2020-04-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of polymerized type V pilin reveals assembly mechanism involving protease-mediated strand exchange.
Nat Microbiol, 5, 2020
6JZK
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BU of 6jzk by Molmil
Structure of FimA type-1 (FimA1) prepilin of the type V major fimbrium
Descriptor: GLYCEROL, Major fimbrium subunit FimA type-1, S,R MESO-TARTARIC ACID, ...
Authors:Okada, K, Shoji, M, Nakayam, K, Imada, K.
Deposit date:2019-05-02
Release date:2020-04-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of polymerized type V pilin reveals assembly mechanism involving protease-mediated strand exchange.
Nat Microbiol, 5, 2020
2FYH
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BU of 2fyh by Molmil
Solution structure of the 2'-5' RNA ligase-like protein from Pyrococcus furiosus
Descriptor: putative integral membrane transport protein
Authors:Okada, K, Matsuda, T, Sakamoto, T, Muto, Y, Yokoyama, S, Kanai, A, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-02-08
Release date:2007-02-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Characterization of a heat-stable enzyme possessing GTP-dependent RNA ligase activity from a hyperthermophilic archaeon, Pyrococcus furiosus
Rna, 15, 2009
1AUG
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BU of 1aug by Molmil
CRYSTAL STRUCTURE OF THE PYROGLUTAMYL PEPTIDASE I FROM BACILLUS AMYLOLIQUEFACIENS
Descriptor: PYROGLUTAMYL PEPTIDASE-1
Authors:Odagaki, Y, Hayashi, A, Okada, K, Hirotsu, K, Kabashima, T, Ito, K, Yoshimoto, T, Tsuru, D, Sato, M, Clardy, J.
Deposit date:1997-08-26
Release date:1999-03-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of pyroglutamyl peptidase I from Bacillus amyloliquefaciens reveals a new structure for a cysteine protease.
Structure Fold.Des., 7, 1999
8WO8
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BU of 8wo8 by Molmil
Crystal Structure of an RNA-binding protein, FAU-1, from Pyrococcus furiosus
Descriptor: Probable ribonuclease FAU-1, RNA (5'-R(P*AP*UP*A)-3')
Authors:Kawai, G, Okada, K, Baba, S, Sato, A, Sakamoto, T, Kanai, A.
Deposit date:2023-10-06
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Homo-trimeric structure of the ribonuclease for rRNA processing, FAU-1, from Pyrococcus furiosus.
J.Biochem., 2024
1BJW
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BU of 1bjw by Molmil
ASPARTATE AMINOTRANSFERASE FROM THERMUS THERMOPHILUS
Descriptor: ASPARTATE AMINOTRANSFERASE, PHOSPHATE ION
Authors:Nakai, T, Okada, K, Kuramitsu, S, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1998-06-30
Release date:1999-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate.
Biochemistry, 38, 1999
6JPL
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BU of 6jpl by Molmil
The X-ray structure of yeast tRNA methyltransferase Trm7-Trm734 in complex with S-adenosyl-L-methionine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Hirata, A, Okada, K, Yoshii, K, Shiraisi, H, Saijo, S, Yonezawa, K, Shimizu, N, Hori, H.
Deposit date:2019-03-27
Release date:2019-10-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
Nucleic Acids Res., 47, 2019
1BGY
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BU of 1bgy by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
Descriptor: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
Authors:Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
Deposit date:1998-06-02
Release date:1999-01-06
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
4PHU
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BU of 4phu by Molmil
Crystal structure of Human GPR40 bound to allosteric agonist TAK-875
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DIMETHYL SULFOXIDE, Free fatty acid receptor 1,Lysozyme, ...
Authors:Srivastava, A, Yano, J.K, Hirozane, Y, Kefala, G, Snell, G, Lane, W, Gruswitz, F, Ivetac, A, Aertgeerts, K, Nguyen, J, Jennings, A, Okada, K.
Deposit date:2014-05-07
Release date:2014-07-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
1BE3
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BU of 1be3 by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
Descriptor: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
Authors:Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
Deposit date:1998-05-19
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
2HI7
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BU of 2hi7 by Molmil
Crystal structure of DsbA-DsbB-ubiquinone complex
Descriptor: Disulfide bond formation protein B, Thiol:disulfide interchange protein dsbA, UBIQUINONE-1, ...
Authors:Inaba, K, Murakami, S, Suzuki, M, Nakagawa, A, Yamashita, E, Okada, K, Ito, K.
Deposit date:2006-06-29
Release date:2006-12-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal Structure of the DsbB-DsbA Complex Reveals a Mechanism of Disulfide Bond Generation
Cell(Cambridge,Mass.), 127, 2006
5WJJ
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BU of 5wjj by Molmil
Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
Descriptor: Mitogen-activated protein kinase 14, N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide
Authors:Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C.
Deposit date:2017-07-23
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
Bioorg. Med. Chem., 26, 2018

 

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