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1UJ3
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CRYSTAL STRUCTURE OF A HUMANIZED FAB FRAGMENT OF ANTI-TISSUE-FACTOR ANTIBODY IN COMPLEX WITH TISSUE FACTOR
Descriptor:IgG Fab light chain, IgG Fab heavy chain, tissue factor
Authors:Ohto, U., Mizutani, R., Nakamura, M., Adachi, H., Satow, Y.
Deposit date:2003-07-25
Release date:2004-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor.
J.Synchrotron Radiat., 11, 2004
2E56
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CRYSTAL STRUCTURE OF HUMAN MD-2
Descriptor:Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, MYRISTIC ACID
Authors:Ohto, U., Satow, Y.
Deposit date:2006-12-19
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Science, 316, 2007
2E59
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CRYSTAL STRUCTURE OF HUMAN MD-2 IN COMPLEX WITH LIPID IVA
Descriptor:Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, ...
Authors:Ohto, U., Satow, Y.
Deposit date:2006-12-19
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
Science, 316, 2007
3B2D
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CRYSTAL STRUCTURE OF HUMAN RP105/MD-1 COMPLEX
Descriptor:CD180 antigen, Lymphocyte antigen 86, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-07-29
Release date:2011-11-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
3T6Q
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CRYSTAL STRUCTURE OF MOUSE RP105/MD-1 COMPLEX
Descriptor:CD180 antigen, Lymphocyte antigen 86, COPPER (II) ION, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-07-28
Release date:2011-11-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
3THC
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CRYSTAL STRUCTURE OF HUMAN BETA-GALACTOSIDASE IN COMPLEX WITH GALACTOSE
Descriptor:Beta-galactosidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-08-18
Release date:2011-12-07
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human beta-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases
J.Biol.Chem., 287, 2012
3THD
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CRYSTAL STRUCTURE OF HUMAN BETA-GALACTOSIDASE IN COMPLEX WITH 1-DEOXYGALACTONOJIRIMYCIN
Descriptor:Beta-galactosidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2011-08-18
Release date:2011-12-07
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of human beta-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases
J.Biol.Chem., 287, 2012
3VQ1
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID IVA COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
3VQ2
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
3WPB
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CRYSTAL STRUCTURE OF HORSE TLR9 (UNLIGANDED FORM)
Descriptor:Toll-like receptor 9, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPC
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CRYSTAL STRUCTURE OF HORSE TLR9 IN COMPLEX WITH AGONISTIC DNA1668_12MER
Descriptor:Toll-like receptor 9, DNA (5'-D(*CP*AP*TP*GP*AP*CP*GP*TP*TP*CP*CP*T)-3'), N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPD
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CRYSTAL STRUCTURE OF HORSE TLR9 IN COMPLEX WITH INHIBITORY DNA4084
Descriptor:Toll-like receptor 9, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*G)-3'), SULFATE ION, ...
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPE
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CRYSTAL STRUCTURE OF BOVINE TLR9 IN COMPLEX WITH AGONISTIC DNA1668_12MER
Descriptor:Toll-like receptor 9, DNA (5'-D(*CP*AP*TP*GP*AP*CP*GP*TP*TP*CP*CP*T)-3')
Authors:Ohto, U., Tanji, H., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPF
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CRYSTAL STRUCTURE OF MOUSE TLR9 (UNLIGANDED FORM)
Descriptor:Toll-like receptor 9, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Ohto, U., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.959 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPG
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CRYSTAL STRUCTURE OF MOUSE TLR9 IN COMPLEX WITH INHIBITORY DNA4084 (FORM 1)
Descriptor:Toll-like receptor 9, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*GP*AP*A)-3'), N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPH
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CRYSTAL STRUCTURE OF MOUSE TLR9 IN COMPLEX WITH INHIBITORY DNA4084 (FORM 2)
Descriptor:Toll-like receptor 9, DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*GP*GP*GP*AP*A)-3'), N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.327 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
3WPI
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CRYSTAL STRUCTURE OF MOUSE TLR9 IN COMPLEX WITH INHIBITORY DNA_SUPER
Descriptor:Toll-like receptor 9, DNA (5'-D(*CP*CP*TP*CP*AP*AP*TP*AP*GP*GP*GP*TP*GP*AP*GP*GP*GP*G)-3'), N-ACETYL-D-GLUCOSAMINE
Authors:Ohto, U., Shimizu, T.
Deposit date:2014-01-11
Release date:2015-02-11
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520, 2015
4G8A
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CRYSTAL STRUCTURE OF HUMAN TLR4 POLYMORPHIC VARIANT D299G AND T399I IN COMPLEX WITH MD-2 AND LPS
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-07-23
Release date:2012-10-17
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analyses of human Toll-like receptor 4 polymorphisms D299G and T399I
J.Biol.Chem., 287, 2012
5JK9
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CRYSTAL STRUCTURE OF HUMAN IZUMO1
Descriptor:Izumo sperm-egg fusion protein 1, N-ACETYL-D-GLUCOSAMINE
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKA
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CRYSTAL STRUCTURE OF HUMAN JUNO (CRYSTAL FORM 1)
Descriptor:Sperm-egg fusion protein Juno, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKB
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CRYSTAL STRUCTURE OF HUMAN JUNO (CRYSTAL FORM 2)
Descriptor:Sperm-egg fusion protein Juno, CHLORIDE ION
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKC
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CRYSTAL STRUCTURE OF HUMAN IZUMO1-JUNO COMPLEX (CRYSTAL FORM 1)
Descriptor:Izumo sperm-egg fusion protein 1, Sperm-egg fusion protein Juno, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKD
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CRYSTAL STRUCTURE OF HUMAN IZUMO1-JUNO COMPLEX (CRYSTAL FORM 2)
Descriptor:Izumo sperm-egg fusion protein 1, Sperm-egg fusion protein Juno, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5JKE
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CRYSTAL STRUCTURE OF HUMAN IZUMO1-JUNO COMPLEX (CRYSTAL FORM 3)
Descriptor:Izumo sperm-egg fusion protein 1, Sperm-egg fusion protein Juno, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2016-04-26
Release date:2016-06-22
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization
Nature, 534, 2016
5Y3J
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CRYSTAL STRUCTURE OF HORSE TLR9 IN COMPLEX WITH TWO DNAS (CPG DNA AND TCGCAC DNA)
Descriptor:Toll-like receptor 9, DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*CP*GP*CP*AP*C)-3'), ...
Authors:Ohto, U., Ishida, H., Shimizu, T.
Deposit date:2017-07-29
Release date:2018-04-18
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
Immunity, 48, 2018