Author results

2WBK
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STRUCTURE OF THE MICHAELIS COMPLEX OF BETA-MANNOSIDASE, MAN2A, PROVIDES INSIGHT INTO THE CONFORMATIONAL ITINERARY OF MANNOSIDE HYDROLYSIS
Descriptor:BETA-MANNOSIDASE, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Offen, W.A., Zechel, D.L., Withers, S.G., Gilbert, H.J., Davies, G.J.
Deposit date:2009-03-02
Release date:2009-03-17
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the Michaelis Complex of Beta-Mannosidase, Man2A, Provides Insight Into the Conformational Itinerary of Mannoside Hydrolysis.
Cell(Cambridge,Mass.), 18, 2009
4UZU
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THREE-DIMENSIONAL STRUCTURE OF A VARIANT `TERMAMYL-LIKE' GEOBACILLUS STEAROTHERMOPHILUS ALPHA-AMYLASE AT 1.9 A RESOLUTION
Descriptor:ALPHA-AMYLASE, GLYCINE, CALCIUM ION, ...
Authors:Offen, W.A., Anderson, C., Borchert, T.V., Wilson, K.S., Davies, G.J.
Deposit date:2014-09-09
Release date:2015-01-14
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-Dimensional Structure of a Variant `Termamyl-Like' Geobacillus Stearothermophilus Alpha-Amylase at 1.9 A Resolution
Acta Crystallogr.,Sect.F, 71, 2015
2RBI
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STRUCTURE OF BINASE MUTANT HIS 101 ASN
Descriptor:RIBONUCLEASE
Authors:Offen, W.A., Okorokov, A.L.
Deposit date:1996-11-12
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations.
Protein Eng., 10, 1997
5OSS
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BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH GLUCO-1H-IMIDAZOLE
Descriptor:Beta-glucosidase A, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Offen, W.A., Schroeder, S.P., Davies, G.J., Overkleeft, H.S.
Deposit date:2017-08-18
Release date:2018-04-11
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Gluco-1 H-imidazole: A New Class of Azole-Type beta-Glucosidase Inhibitor.
J. Am. Chem. Soc., 140, 2018
6HA9
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STRUCTURE OF AN ENDO-XYLOGLUCANASE FROM CELLVIBRIO JAPONICUS COMPLEXED WITH XXXG(2F)-BETA-DNP
Descriptor:Cellulase, putative, cel5D, ...
Authors:Offen, W.A., Davies, G.J.
Deposit date:2018-08-07
Release date:2018-10-03
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis and application of a highly branched, mechanism-based 2-deoxy-2-fluoro-oligosaccharide inhibitor of endo-xyloglucanases.
Org. Biomol. Chem., 16, 2018
1B0N
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SINR PROTEIN/SINI PROTEIN COMPLEX
Descriptor:PROTEIN (SINR PROTEIN), PROTEIN (SINI PROTEIN), ZINC ION
Authors:Lewis, R.J., Brannigan, J.A., Offen, W.A., Smith, I., Wilkinson, A.J.
Deposit date:1998-11-11
Release date:1999-01-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex.
J.Mol.Biol., 283, 1998
1ODS
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CEPHALOSPORIN C DEACETYLASE FROM BACILLUS SUBTILIS
Descriptor:CEPHALOSPORIN C DEACETYLASE, CHLORIDE ION, MAGNESIUM ION
Authors:Vincent, F., Charnock, S.J., Verschueren, K.H.G., Turkenburg, J.P., Scott, D.J., Offen, W.A., Roberts, S., Pell, G., Gilbert, H.J., Brannigan, J.A., Davies, G.J.
Deposit date:2003-02-20
Release date:2003-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multifunctional Xylooligosaccharide/Cephalosporin C Deacetylase Revealed by the Hexameric Structure of the Bacillus Subtilis Enzyme at 1.9A Resolution
J.Mol.Biol., 330, 2003
1ODT
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CEPHALOSPORIN C DEACETYLASE MUTATED, IN COMPLEX WITH ACETATE
Descriptor:CEPHALOSPORIN C DEACETYLASE, ACETATE ION
Authors:Vincent, F., Charnock, S.J., Verschueren, K.H.G., Turkenburg, J.P., Scott, D.J., Offen, W.A., Roberts, S., Pell, G., Gilbert, H.J., Brannigan, J.A., Davies, G.J.
Deposit date:2003-02-20
Release date:2003-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Multifunctional Xylooligosaccharide/Cephalosporin C Deacetylase Revealed by the Hexameric Structure of the Bacillus Subtilis Enzyme at 1.9A Resolution
J.Mol.Biol., 330, 2003
2VCE
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CHARACTERIZATION AND ENGINEERING OF THE BIFUNCTIONAL N- AND O- GLUCOSYLTRANSFERASE INVOLVED IN XENOBIOTIC METABOLISM IN PLANTS
Descriptor:HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE, 2,4,5-trichlorophenol, ...
Authors:Brazier-Hicks, M., Offen, W.A., Gershater, M.C., Revett, T.J., Lim, E.K., Bowles, D.J., Davies, G.J., Edwards, R.
Deposit date:2007-09-20
Release date:2007-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VCH
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CHARACTERIZATION AND ENGINEERING OF THE BIFUNCTIONAL N- AND O- GLUCOSYLTRANSFERASE INVOLVED IN XENOBIOTIC METABOLISM IN PLANTS
Descriptor:HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL
Authors:Brazier-Hicks, M., Offen, W.A., Gershater, M.C., Revett, T.J., Lim, E.K., Bowles, D.J., Davies, G.J., Edwards, R.
Deposit date:2007-09-24
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VG8
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CHARACTERIZATION AND ENGINEERING OF THE BIFUNCTIONAL N- AND O- GLUCOSYLTRANSFERASE INVOLVED IN XENOBIOTIC METABOLISM IN PLANTS
Descriptor:HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Brazier-Hicks, M., Offen, W.A., Gershater, M.C., Revett, T.J., Lim, E.K., Bowles, D.J., Davies, G.J., Edwards, R.
Deposit date:2007-11-09
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VJX
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VL4
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VMF
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-01-25
Release date:2008-04-01
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VO5
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (1R,4R,5R,7R,8R)-2-Benzyl-5-hydroxymethyl-2-aza-bicyclo[2.2.2]octane-4,7,8-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-02-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VOT
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (5R,6R,7S,8R)-6,7,8-trihydroxy-5-(hydroxymethyl)-2-[(phenylamino)methyl]-5,6,7,8-tetrahydro-1H-imidazo[1,2-a]pyridin-4-ium, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.N., Offen, W.A., Smith, N., Dumon, C., Moreland, C., Gratien, J., Heck, M.-P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-02-20
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VQT
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (2Z,3R,4S,5R,6R)-2-[(2-aminoethyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-18
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VQU
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, 1,2-ETHANEDIOL, (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-18
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VR4
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TRANSITION-STATE MIMICRY IN MANNOSIDE HYDROLYSIS: CHARACTERISATION OF TWENTY SIX INHIBITORS AND INSIGHT INTO BINDING FROM LINEAR FREE ENERGY RELATIONSHIPS AND 3-D STRUCTURE
Descriptor:BETA-MANNOSIDASE, (2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-25
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2YIH
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STRUCTURE OF A PAENIBACILLUS POLYMYXA XYLOGLUCANASE FROM GH FAMILY 44 WITH XYLOGLUCAN
Descriptor:CEL44C, CALCIUM ION, CHLORIDE ION, ...
Authors:Ariza, A., Eklof, J.M., Spadiut, O., Offen, W.A., Roberts, S.M., Besenmatter, W., Friis, E.P., Skjot, M., Wilson, K.S., Brumer, H., Davies, G.
Deposit date:2011-05-13
Release date:2011-06-08
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
2YJQ
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STRUCTURE OF A PAENIBACILLUS POLYMYXA XYLOGLUCANASE FROM GLYCOSIDE HYDROLASE FAMILY 44
Descriptor:CEL44C, TETRAHYDROOXAZINE, BETA-D-GLUCOSE, ...
Authors:Ariza, A., Eklof, J.M., Spadiut, O., Offen, W.A., Roberts, S.M., Besenmatter, W., Friis, E.P., Skjot, M., Wilson, K.S., Brumer, H., Davies, G.
Deposit date:2011-05-23
Release date:2011-06-15
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
2YKK
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STRUCTURE OF A PAENIBACILLUS POLYMYXA XYLOGLUCANASE FROM GLYCOSIDE HYDROLASE FAMILY 44
Descriptor:CEL44C, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Ariza, A., Eklof, J.M., Spadiut, O., Offen, W.A., Roberts, S.M., Besenmatter, W., Friis, E.P., Skjot, M., Wilson, K.S., Brumer, H., Davies, G.
Deposit date:2011-05-27
Release date:2011-06-22
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
3ZQ9
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STRUCTURE OF A PAENIBACILLUS POLYMYXA XYLOGLUCANASE FROM GLYCOSIDE HYDROLASE FAMILY 44
Descriptor:XYLOGLUCANASE, (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, BETA-D-GLUCOSE, ...
Authors:Ariza, A., Eklof, J.M., Spadiut, O., Offen, W.A., Roberts, S.M., Besenmatter, W., Friis, E.P., Skjot, M., Wilson, K.S., Brumer, H., Davies, G.
Deposit date:2011-06-08
Release date:2011-06-22
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
4BMX
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NATIVE STRUCTURE OF FUTALOSINE HYDROLASE OF HELICOBACTER PYLORI STRAIN 26695
Descriptor:MTA/SAH NUCLEOSIDASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE
Authors:Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.
Deposit date:2013-05-12
Release date:2013-09-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
4BMY
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STRUCTURE OF FUTALOSINE HYDROLASE MUTANT OF HELICOBACTER PYLORI STRAIN 26695
Descriptor:MTA/SAH NUCLEOSIDASE, SULFATE ION
Authors:Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.
Deposit date:2013-05-12
Release date:2013-09-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
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