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5KDI
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HOW FAPP2 SELECTS SIMPLE GLYCOSPHINGOLIPIDS USING THE GLTP-FOLD
Descriptor:Pleckstrin homology domain-containing family A member 8, (~{Z})-~{N}-[(~{E},2~{S},3~{R})-1-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-octadec-4-en-2-yl]octadec-9-enamide
Authors:Ochoa-Lizarralde, B., Popov, A.N., Samygina, V.R., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2016-06-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:How FAPP2 Selects Simple Glycosphingolipids Using the GLTP-fold: Structural Insights into Specificity in the GLTP-Family
J.Biol.Chem., 2017
3RIC
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CRYSTAL STRUCTURE OF D48V||A47D MUTANT OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO-GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN (24:1)
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-04-13
Release date:2012-02-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3RWV
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CRYSTAL STRUCTURE OF APO-FORM OF HUMAN GLYCOLIPID TRANSFER PROTEIN AT 1.5 A RESOLUTION
Descriptor:Glycolipid transfer protein, SULFATE ION
Authors:Samygina, V., Cabo-Bilbao, A., Popov, A.N., Ochoa-Lizarralde, B., Goni-de-Cerio, F., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-09
Release date:2012-02-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3RZN
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CRYSTAL STRUCTURE OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO-GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN (24:1)
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Cabo-Bilbao, A., Popov, A.N., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-12
Release date:2012-02-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3S0I
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH 3-O-SULFO GALACTOSYLCERAMIDE CONTAINING NERVONOYL ACYL CHAIN
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE
Authors:Samygina, V., Popov, A.N., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-13
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3S0K
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CRYSTAL STRUCTURE OF HUMAN GLYCOLIPID TRANSFER PROTEIN COMPLEXED WITH GLUCOSYLCERAMIDE CONTAINING OLEOYL ACYL CHAIN (18:1)
Descriptor:Glycolipid transfer protein, (9Z)-N-[(2S,3R,4E)-1-(beta-D-glucopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]octadec-9-enamide, NICKEL (II) ION
Authors:Cabo-Bilbao, A., Samygina, V., Popov, A.N., Ochoa-Lizarralde, B., Goni-de-Cerio, F., Patel, D.J., Brown, R.E., Malinina, L.
Deposit date:2011-05-13
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
4GH0
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE
Authors:Samygina, V.R., Cabo-Bilbao, A., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-07
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GHP
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CRYSTAL STRUCTURE OF D48V||A47D MUTANT OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-08
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GIX
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Malinina, L.
Deposit date:2012-08-09
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GJQ
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE (ORTHORHOMBIC FORM;TWO SUBUNITS IN ASYMMETRIC UNIT)
Descriptor:Glycolipid transfer protein, (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, HEXANE
Authors:Cabo-Bilbao, A., Goni-de-Cerio, F., Samygina, V.R., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-08-10
Release date:2013-06-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GXD
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Popov, A.N., Malinina, L.
Deposit date:2012-09-04
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4H2Z
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE, ...
Authors:Samygina, V.R., Ochoa-Lizarralde, B., Malinina, L.
Deposit date:2012-09-13
Release date:2013-04-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4YHH
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TIGECYCLINE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Dhimole, N., Zhou, S., Lopez-Alonso, J.P., Connell, S.R., Fucini, P.
Deposit date:2015-02-27
Release date:2015-04-08
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.417 Å)
Cite:Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
5DM6
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CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS
Descriptor:50S ribosomal protein L1, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Kaminishi, T., Schedlbauer, A., Ochoa-Lizarralde, B., Connell, S.R., Fucini, P.
Deposit date:2015-09-08
Release date:2015-11-11
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5DM7
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CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH HYGROMYCIN A
Descriptor:50S ribosomal protein L1, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Kaminishi, T., Schedlbauer, A., Ochoa-Lizarralde, B., Connell, S.R., Fucini, P.
Deposit date:2015-09-08
Release date:2015-11-11
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5IWA
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE GE81112 PEPTIDE ANTIBIOTIC
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Chieko, N., Masahito, K., Takemoto, C., Yokoyama, S., Connell, S.R., Fucini, P.
Deposit date:2016-03-22
Release date:2016-04-27
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Proc.Natl.Acad.Sci.USA, 113, 2016
4GHS
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE (ORTHOROMBIC FORM; TWO SUBUNITS IN ASYMMETRIC UNIT)
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Popov, A.N., Goni-de-Cerio, F., Cabo-Bilbao, A., Malinina, L.
Deposit date:2012-08-08
Release date:2013-06-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GVT
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CRYSTAL STRUCTURE OF D48V MUTANT OF HUMAN GLTP BOUND WITH 12:0 DISULFATIDE (HEXAGONAL FORM)
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Cabo-Bilbao, A., Goni-de-Cerio, F., Popov, A.N., Malinina, L.
Deposit date:2012-08-31
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GXG
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CRYSTAL STRUCTURE OF HUMAN GLTP BOUND WITH 12:0 MONOSULFATIDE (ORTHORHOMBIC FORM; FOUR SUBUNITS IN ASYMMETRIC UNIT)
Descriptor:Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R., Cabo-Bilbao, A., Goni-de-Cerio, F., Popov, A.N., Malinina, L.
Deposit date:2012-09-04
Release date:2013-04-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013