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4AKV
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CRYSTAL STRUCTURE OF HUMAN SORTING NEXIN 33 (SNX33)
Descriptor:SORTING NEXIN-33, SULFATE ION
Authors:Oberholzer, A., Froese, D.S., Krojer, T., Shrestha, L., Filippakopoulos, P., Muniz, J.R.C., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Yue, W.W.
Deposit date:2012-02-29
Release date:2012-08-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Structure of Human Sorting Nexin 33
To be Published
4V06
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CRYSTAL STRUCTURE OF HUMAN TRYPTOPHAN HYDROXYLASE 2 (TPH2), CATALYTIC DOMAIN
Descriptor:TRYPTOPHAN 5-HYDROXYLASE 2, IMIDAZOLE, FE (III) ION
Authors:Kopec, J., Oberholzer, A., Fitzpatrick, F., Newman, J., Tallant, C., Kiyani, W., Shrestha, L., Burgess-Brown, N., von Delft, F., Arrowsmith, C., Edwards, A., Bountra, C., Yue, W.W.
Deposit date:2014-09-11
Release date:2014-10-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal Structure of Human Tryptophane Hydroxylase 2 (Tph2), Catalytic Domain
To be Published
3ZI1
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CRYSTAL STRUCTURE OF HUMAN GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 (GLOD4)
Descriptor:GLYOXALASE DOMAIN-CONTAINING PROTEIN 4, 1,2-ETHANEDIOL
Authors:Oberholzer, A., Kiyani, W., Shrestha, L., Vollmar, M., Krojer, T., Froese, D.S., Williams, E., von Delft, F., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A., Bountra, C., Yue, W.W.
Deposit date:2012-12-30
Release date:2013-01-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Human Glyoxalase Domain- Containing Protein 4 (Glod4)
To be Published
4AZE
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HUMAN DYRK1A IN COMPLEX WITH LEUCETTINE L41
Descriptor:DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A, 5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4H-imidazol-4-one
Authors:Elkins, J.M., Soundararajan, M., Muniz, J.R.C., Tahtouh, T., Burgy, G., Durieu, E., Lozach, O., Cochet, C., Schmid, R.S., Lo, D.C., Delhommel, F., Carreaux, F., Bazureau, J.P., Meijer, L., Edwards, A., Bountra, C., Knapp, S.
Deposit date:2012-06-25
Release date:2012-09-05
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Selectivity, Co-Crystal Structures and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B.
J.Med.Chem., 55, 2012
4AZF
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HUMAN DYRK2 IN COMPLEX WITH LEUCETTINE L41
Descriptor:DYRK2 DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 2, 5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4H-imidazol-4-one, 1,2-ETHANEDIOL, ...
Authors:Elkins, J.M., Soundararajan, M., Muniz, J.R.C., Tahtouh, T., Burgy, G., Durieu, E., Lozach, O., Cochet, C., Schmid, R.S., Lo, D.C., Delhommel, F., Carreaux, F., Bazureau, J.P., Meijer, L., Edwards, A., Bountra, C., Knapp, S.
Deposit date:2012-06-25
Release date:2012-09-05
Last modified:2012-11-21
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Selectivity, Co-Crystal Structures and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B.
J.Med.Chem., 55, 2012