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5ANM
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BU of 5anm by Molmil
Crystal structure of IgE Fc in complex with a neutralizing antibody
Descriptor: IG EPSILON CHAIN C REGION, IMMUNOGLOBULIN G, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cohen, E.S, Dobson, C.L, Kack, H, Wang, B, Sims, D.A, Lloyd, C.O, England, E, Rees, D.G, Guo, H, Karagiannis, S.N, O'Brien, S, Persdotter, S, Ekdahl, H, Butler, R, Keyes, F, Oakley, S, Carlsson, M, Briend, E, Wilkinson, T, Anderson, I.K, Monk, P.D, vonWachenfeldt, K, Eriksson, P.O, Gould, H.J, Vaughan, T.J, May, R.D.
Deposit date:2015-09-07
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Novel Ige-Neutralizing Antibody for the Treatment of Severe Uncontrolled Asthma.
Mabs, 6, 2015
6NT2
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BU of 6nt2 by Molmil
type 1 PRMT in complex with the inhibitor GSK3368715
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine, ...
Authors:Concha, N.O.
Deposit date:2019-01-28
Release date:2019-07-10
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.
Cancer Cell, 36, 2019
7UKZ
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BU of 7ukz by Molmil
CDK11 in complex with small molecule inhibitor OTS964
Descriptor: Cyclin-dependent kinase 11B, OTS964, SULFATE ION
Authors:Kelso, S, Sicheri, F.
Deposit date:2022-04-03
Release date:2022-10-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964.
Structure, 30, 2022
4HJ0
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BU of 4hj0 by Molmil
Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
Descriptor: Gastric inhibitory polypeptide receptor, Gipg013 Fab, Antagonizing antibody to the GIP Receptor, ...
Authors:Madhurantakam, C, Ravn, P, Gruetter, M.G, Jackson, R.H.
Deposit date:2012-10-12
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor.
J.Biol.Chem., 288, 2013

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