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5I7M
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BU of 5i7m by Molmil
Crystal structure of Y345F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2016-02-17
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
6DU0
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BU of 6du0 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DI6
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BU of 6di6 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DTV
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BU of 6dtv by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395F mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DI2
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BU of 6di2 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y397L mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DTZ
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BU of 6dtz by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, ...
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5DQO
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BU of 5dqo by Molmil
Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2015-09-15
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
5A7U
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BU of 5a7u by Molmil
Single-particle cryo-EM of co-translational folded adr1 domain inside the E. coli ribosome exit tunnel.
Descriptor: REGULATORY PROTEIN ADR1, ZINC ION
Authors:Nilsson, O.B, Hedman, R, Marino, J, Wickles, S, Bischoff, L, Johansson, M, Muller-Lucks, A, Trovato, F, Puglisi, J.D, O'Brien, E, Beckmann, R, von Heijne, G.
Deposit date:2015-07-10
Release date:2015-09-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cotranslational Protein Folding Inside the Ribosome Exit Tunnel.
Cell Rep., 12, 2015
6MOM
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BU of 6mom by Molmil
Crystal structure of human Interleukin-1 receptor associated Kinase 4 (IRAK 4, CID 100300) in complex with compound NCC00371481 (BSI 107591)
Descriptor: 1,2-ETHANEDIOL, 6-[7-methoxy-6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-N-[(3R)-pyrrolidin-3-yl]pyridin-2-amine, Interleukin-1 receptor-associated kinase 4
Authors:Abendroth, J, Mayclin, S.J, Lorimer, D.D, Starczynowski, D, Hoyt, S, Tawa, G, Thomas, C.
Deposit date:2018-10-04
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
Sci Transl Med, 11, 2019
7WAY
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BU of 7way by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state
Descriptor: DNA (27-MER), DNA (33-MER), RNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB1
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BU of 7wb1 by Molmil
PlmCasX-sgRNAv2-dsDNA ternary complex at nts loading state
Descriptor: NTS-DNA, RNA (121-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WAZ
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BU of 7waz by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at ts loading state
Descriptor: NTS-DNA, RNA (115-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
7WB0
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BU of 7wb0 by Molmil
PlmCasX-sgRNAv1-dsDNA ternary complex at nts loading state with flexible H2 domain
Descriptor: NTS-DNA, RNA (115-MER), TS-DNA, ...
Authors:Zhang, S, Liu, J.J.G.
Deposit date:2021-12-15
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Mol.Cell, 82, 2022
1EBV
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BU of 1ebv by Molmil
OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID SALICYLOYL-AMINO-ESTER, ...
Authors:Loll, P.J, Sharkey, C.T, O'Connor, S.J, Fitzgerald, D.J.
Deposit date:2000-01-24
Release date:2000-02-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions.
Mol.Pharmacol., 60, 2001
6DHW
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BU of 6dhw by Molmil
Crystal structure of primase iron-sulfur domain (266-457)
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Holt, M.E, Salay, L.E, Chazin, W.J.
Deposit date:2018-05-21
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.013 Å)
Cite:Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.
PLoS ONE, 13, 2018

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