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2MUS
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BU of 2mus by Molmil
HADDOCK calculated model of LIN5001 bound to the HET-s amyloid
Descriptor: 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid, Heterokaryon incompatibility protein s
Authors:Hermann, U.S, Schuetz, A.K, Shirani, H, Saban, D, Nuvolone, M, Huang, D.H, Li, B, Ballmer, B, Aslund, A.K.O, Mason, J.J, Rushing, E, Budka, H, Hammarstrom, P, Bockmann, A, Caflisch, A, Meier, B.H, Nilsson, P.K.R, Hornemann, S, Aguzzi, A.
Deposit date:2014-09-16
Release date:2017-02-01
Last modified:2018-06-13
Method:SOLUTION NMR
Cite:Structure-based drug design identifies polythiophenes as antiprion compounds.
Sci Transl Med, 7, 2015
8P88
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BU of 8p88 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody C4
Descriptor: CHLORIDE ION, Light Chain H3, Nanobody C4, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2023-05-31
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
8P89
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BU of 8p89 by Molmil
X-ray structure of cardiotoxic light chain H3 in complex to neutralizing nanobody B5
Descriptor: CHLORIDE ION, Light chain H3, Nanobody B5
Authors:Broggini, L, Ricagno, S.
Deposit date:2023-05-31
Release date:2024-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.187 Å)
Cite:Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
J.Mol.Biol., 435, 2023
7ZH7
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BU of 7zh7 by Molmil
Cryo-EM structure of ex vivo AA amyloid from renal tissue of a short hair cat deceased in a shelter
Descriptor: Serum amyloid A protein
Authors:Schulte, T, Chaves-Sanjuan, A, Ricagno, S.
Deposit date:2022-04-05
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter.
Nat Commun, 13, 2022
8CPE
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BU of 8cpe by Molmil
CryoEM structure of AL55 amyloid fibrils extracted from the kidney of an AL amyloidosis patient.
Descriptor: Immunoglobulin lambda light chain
Authors:Puri, S, Schulte, T, Chaves-Sanjuan, A, Ricagno, S.
Deposit date:2023-03-02
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The Cryo-EM STRUCTURE of Renal Amyloid Fibril Suggests Structurally Homogeneous Multiorgan Aggregation in AL Amyloidosis.
J.Mol.Biol., 435, 2023

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PDB entries from 2024-04-17

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