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7UWE
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BU of 7uwe by Molmil
CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
7UWH
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BU of 7uwh by Molmil
CryoEM Structure of E. coli Transcription-Coupled Ribonucleotide Excision Repair (TC-RER) complex bound to ribonucleotide substrate
Descriptor: DNA (59-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Grower, M, Bharati, B, Proshkin, S, Epshtein, V, Svetlov, V, Nudler, E, Shamovsky, I.
Deposit date:2022-05-03
Release date:2023-05-31
Last modified:2023-06-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:RNA polymerase drives ribonucleotide excision DNA repair in E. coli.
Cell, 186, 2023
6O96
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BU of 6o96 by Molmil
Dot1L bound to the H2BK120 Ubiquitinated nucleosome
Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Vasilyev, N, Chen, R, Nudler, E, Armache, J.-P, Armache, K.-J.
Deposit date:2019-03-13
Release date:2019-04-24
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
Mol.Cell, 74, 2019
8FTD
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BU of 8ftd by Molmil
Structure of Escherichia coli CedA in complex with transcription initiation complex
Descriptor: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, M, Vassyliev, N, Nudler, E.
Deposit date:2023-01-11
Release date:2024-01-10
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:General transcription factor from Escherichia coli with a distinct mechanism of action.
Nat.Struct.Mol.Biol., 31, 2024
7U5C
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BU of 7u5c by Molmil
Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state
Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
Authors:Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T.
Deposit date:2022-03-02
Release date:2022-05-18
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state.
Nat.Struct.Mol.Biol., 29, 2022
6XAV
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BU of 6xav by Molmil
CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Kim, H.K, Walz, T, Nudler, E.
Deposit date:2020-06-04
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
6XAS
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BU of 6xas by Molmil
CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hao, Z.T, Kim, H.K, Walz, T, Nudler, E.
Deposit date:2020-06-04
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
6AWB
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BU of 6awb by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWD
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BU of 6awd by Molmil
Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWC
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BU of 6awc by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
8FVR
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BU of 8fvr by Molmil
CryoEM structure of E.coli transcription elongation complex
Descriptor: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Duan, W, Serganov, A.
Deposit date:2023-01-19
Release date:2023-04-05
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Control of transcription elongation and DNA repair by alarmone ppGpp.
Nat.Struct.Mol.Biol., 30, 2023
8FVW
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BU of 8fvw by Molmil
CryoEM structure of E.coli transcription elongation complex bound to ppGpp
Descriptor: DNA (53-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Duan, W, Serganov, A.
Deposit date:2023-01-19
Release date:2023-04-05
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Control of transcription elongation and DNA repair by alarmone ppGpp.
Nat.Struct.Mol.Biol., 30, 2023
4WQS
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BU of 4wqs by Molmil
Thermus thermophilus RNA polymerase backtracked complex
Descriptor: DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Murayama, Y, Sekine, S, Yokoyama, S.
Deposit date:2014-10-22
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.306 Å)
Cite:The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
4WQT
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BU of 4wqt by Molmil
Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murayama, Y, Sekine, S, Yokoyama, S.
Deposit date:2014-10-22
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
7EGS
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BU of 7egs by Molmil
The crystal structure of lobe domain of E. coli RNA polymerase complexed with the C-terminal domain of UvrD
Descriptor: DNA helicase II, DNA-directed RNA polymerase subunit beta, GLYCEROL
Authors:Zheng, F, Shen, L, Li, L, Zhang, Y.
Deposit date:2021-03-26
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
3EQL
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BU of 3eql by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I.
Deposit date:2008-09-30
Release date:2008-10-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Transcription inactivation through local refolding of the RNA polymerase structure.
Nature, 457, 2009
8SVF
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BU of 8svf by Molmil
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Descriptor: DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ...
Authors:Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J.
Deposit date:2023-05-16
Release date:2023-08-30
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Sci Adv, 9, 2023
8T9F
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BU of 8t9f by Molmil
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Descriptor: DNA (122-MER), Histone H2A.Z, Histone H2B 1.1, ...
Authors:Abini-Agbomson, S, Armache, K.-J.
Deposit date:2023-06-23
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.
Mol.Cell, 83, 2023
8THU
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BU of 8thu by Molmil
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Descriptor: DNA (145-MER), DNA (146-MER), Histone H2A.Z, ...
Authors:Abini-Agbomson, S, Armache, K.-J.
Deposit date:2023-07-18
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.
Mol.Cell, 83, 2023
6CDD
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BU of 6cdd by Molmil
Npl4 zinc finger and MPN domains (Chaetomium thermophilum)
Descriptor: Npl4 zinc finger, ZINC ION
Authors:Bodnar, N.O, Rapoport, T.A.
Deposit date:2018-02-08
Release date:2018-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.58233714 Å)
Cite:Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
6CHS
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BU of 6chs by Molmil
Cdc48-Npl4 complex in the presence of ATP-gamma-S
Descriptor: MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A.
Deposit date:2018-02-22
Release date:2018-07-04
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4.
Nat. Struct. Mol. Biol., 25, 2018
7EGT
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BU of 7egt by Molmil
The crystal structure of the C-terminal domain of T. thermophilus UvrD complexed with the N-terminal domain of UvrB
Descriptor: DNA helicase UvrD, UvrABC system protein B
Authors:Zheng, F, Shen, L, Li, L, Zhang, Y.
Deposit date:2021-03-26
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.581 Å)
Cite:Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
6VJY
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BU of 6vjy by Molmil
Cryo-EM structure of Hrd1/Hrd3 monomer
Descriptor: ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3
Authors:Wu, X, Rapoport, T.A.
Deposit date:2020-01-18
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
6VK3
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BU of 6vk3 by Molmil
CryoEM structure of Hrd3/Yos9 complex
Descriptor: Hrd3, Protein OS-9 homolog
Authors:Wu, X, Rapoport, T.A.
Deposit date:2020-01-18
Release date:2020-04-29
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
6VJZ
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BU of 6vjz by Molmil
CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology
Descriptor: Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ...
Authors:Wu, X, Rapoport, T.A.
Deposit date:2020-01-18
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020

 

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