Author results

3T7E
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ATG8 TRANSFER FROM ATG7 TO ATG3: A DISTINCTIVE E1-E2 ARCHITECTURE AND MECHANISM IN THE AUTOPHAGY PATHWAY
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION
Authors:Taherbhoy, A.M., Tait, S.W., Kaiser, S.E., Williams, A.H., Deng, A., Nourse, A., Hammel, M., Kurinov, I., Rock, C.O., Green, D.R., Schulman, B.A.
Deposit date:2011-07-30
Release date:2011-11-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway.
Mol.Cell, 44, 2011
3T7F
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ATG8 TRANSFER FROM ATG7 TO ATG3: A DISTINCTIVE E1-E2 ARCHITECTURE AND MECHANISM IN THE AUTOPHAGY PATHWAY
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7
Authors:Taherbhoy, A.M., Tait, S.W., Kaiser, S.E., Williams, A.H., Deng, A., Nourse, A., Hammel, M., Kurinov, I., Rock, C.O., Green, D.R., Schulman, B.A.
Deposit date:2011-07-30
Release date:2011-11-23
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway.
Mol.Cell, 44, 2011
3T7G
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ATG8 TRANSFER FROM ATG7 TO ATG3: A DISTINCTIVE E1-E2 ARCHITECTURE AND MECHANISM IN THE AUTOPHAGY PATHWAY
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7, Autophagy-related protein 3
Authors:Taherbhoy, A.M., Tait, S.W., Kaiser, S.E., Williams, A.H., Deng, A., Nourse, A., Hammel, M., Kurinov, I., Rock, C.O., Green, D.R., Schulman, B.A.
Deposit date:2011-07-30
Release date:2011-11-23
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway.
Mol.Cell, 44, 2011
3T7H
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ATG8 TRANSFER FROM ATG7 TO ATG3: A DISTINCTIVE E1-E2 ARCHITECTURE AND MECHANISM IN THE AUTOPHAGY PATHWAY
Descriptor:Ubiquitin-like modifier-activating enzyme ATG7
Authors:Taherbhoy, A.M., Tait, S.W., Kaiser, S.E., Williams, A.H., Deng, A., Nourse, A., Hammel, M., Kurinov, I., Rock, C.O., Green, D.R., Schulman, B.A.
Deposit date:2011-07-30
Release date:2011-11-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway.
Mol.Cell, 44, 2011
2HIM
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CRYSTAL STRUCTURE AND ALLOSTERIC REGULATION OF THE CYTOPLASMIC ESCHERICHIA COLI L-ASPARAGINASE I
Descriptor:L-asparaginase 1, ASPARTIC ACID, ASPARAGINE, ...
Authors:Yun, M.K., Nourse, A., White, S.W., Rock, C.O., Heath, R.J.
Deposit date:2006-06-29
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I.
J.Mol.Biol., 369, 2007
2M6N
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3D SOLUTION STRUCTURE OF EMI1 (EARLY MITOTIC INHIBITOR 1)
Descriptor:F-box only protein 5, ZINC ION
Authors:Frye, J.J., Brown, N.G., Petzold, G., Watson, E.R., Royappa, G.R., Nourse, A., Jarvis, M., Kriwacki, R.W., Peters, J., Stark, H., Schulman, B.A.
Deposit date:2013-04-06
Release date:2013-05-29
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.
Nat.Struct.Mol.Biol., 20, 2013
2P2D
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CRYSTAL STRUCTURE AND ALLOSTERIC REGULATION OF THE CYTOPLASMIC ESCHERICHIA COLI L-ASPARAGINASE I
Descriptor:L-ASPARAGINASE I, GLYCEROL
Authors:Yun, M.-K., Nourse, A., White, S.W., Rock, C.O., Heath, R.J.
Deposit date:2007-03-07
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia colil-Asparaginase I
J.Mol.Biol., 369, 2007
2P2N
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CRYSTAL STRUCTURE AND ALLOSTERIC REGULATION OF THE CYTOPLASMIC ESCHERICHIA COLI L-ASPARAGINASE I
Descriptor:L-ASPARAGINASE I, CHLORIDE ION, ASPARTIC ACID, ...
Authors:Yun, M.-K., Nourse, A., White, S.W., Rock, C.O., Heath, R.J.
Deposit date:2007-03-07
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia colil-Asparaginase I
J.Mol.Biol., 369, 2007
3H5A
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CRYSTAL STRUCTURE OF E. COLI MCCB
Descriptor:MccB protein, ZINC ION
Authors:Regni, C.A., Roush, R.F., Miller, D., Nourse, A., Walsh, C.T., Schulman, B.A.
Deposit date:2009-04-21
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H5N
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CRYSTAL STRUCTURE OF E. COLI MCCB + ATP
Descriptor:MccB protein, ZINC ION, MAGNESIUM ION, ...
Authors:Regni, C.A., Roush, R.F., Miller, D., Nourse, A., Walsh, C.T., Schulman, B.A.
Deposit date:2009-04-22
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H5R
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CRYSTAL STRUCTURE OF E. COLI MCCB + SUCCINIMIDE
Descriptor:MccB protein, Microcin C7 analog, ZINC ION, ...
Authors:Regni, C.A., Roush, R.F., Miller, D., Nourse, A., Walsh, C.T., Schulman, B.A.
Deposit date:2009-04-22
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H9G
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CRYSTAL STRUCTURE OF E. COLI MCCB + MCCA-N7ISOASN
Descriptor:MccB protein, Microcin C7 analog, ZINC ION, ...
Authors:Regni, C.A., Roush, R.F., Miller, D., Nourse, A., Walsh, C.T., Schulman, B.A.
Deposit date:2009-04-30
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H9J
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CRYSTAL STRUCTURE OF E. COLI MCCB + AMPCPP + SEMET MCCA
Descriptor:MccB protein, Microcin C7 ANALOG, ZINC ION, ...
Authors:Regni, C.A., Roush, R.F., Miller, D., Nourse, A., Walsh, C.T., Schulman, B.A.
Deposit date:2009-04-30
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H9Q
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CRYSTAL STRUCTURE OF E. COLI MCCB + SEMET MCCA
Descriptor:MccB protein, Microcin C7 ANALOG, ZINC ION, ...
Authors:Regni, C.A., Roush, R.F., Miller, D., Nourse, A., Walsh, C.T., Schulman, B.A.
Deposit date:2009-04-30
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
4N8M
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STRUCTURAL POLYMORPHISM IN THE N-TERMINAL OLIGOMERIZATION DOMAIN OF NPM1
Descriptor:Nucleophosmin, COBALT (II) ION
Authors:Mitrea, D., Royappa, G., Buljan, M., Yun, M., Pytel, N., Satumba, J., Nourse, A., Park, C., Babu, M.M., White, S.W., Kriwacki, R.W.
Deposit date:2013-10-17
Release date:2014-03-12
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural polymorphism in the N-terminal oligomerization domain of NPM1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4R2Y
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CRYSTAL STRUCTURE OF APC11 RING DOMAIN
Descriptor:Anaphase-promoting complex subunit 11, ZINC ION
Authors:Brown, N.G., Watson, E.R., Weissmann, F., Jarvis, M.A., Vanderlinden, R., Grace, C.R.R., Frye, J.J., Dube, P., Qiao, R., Petzold, G., Cho, S.E., Alsharif, O., Bao, J., Zheng, J., Nourse, A., Kurinov, I., Peters, J.M., Stark, H., Schulman, B.A.
Deposit date:2014-08-13
Release date:2014-10-29
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.755 Å)
Cite:Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Mol.Cell, 56, 2014
4R32
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CRYSTAL STRUCTURE ANALYSIS OF PYK2 AND PAXILLIN LD MOTIFS
Descriptor:Protein-tyrosine kinase 2-beta, Paxillin
Authors:Vanarotti, M., Miller, D.J., Guibao, C.D., Nourse, A., Zheng, J.J.
Deposit date:2014-08-13
Release date:2014-09-17
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (3.505 Å)
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
4X9X
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BIOCHEMICAL ROLES FOR CONSERVED RESIDUES IN THE BACTERIAL FATTY ACID BINDING PROTEIN FAMILY
Descriptor:DegV domain-containing protein MW1315, OLEIC ACID, 1,2-ETHANEDIOL
Authors:Broussard, T.C., Miller, D.J., Jackson, P., Nourse, A., Rock, C.O.
Deposit date:2014-12-11
Release date:2016-01-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Biochemical Roles for Conserved Residues in the Bacterial Fatty Acid-binding Protein Family.
J.Biol.Chem., 291, 2016
1H4B
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SOLUTION STRUCTURE OF THE BIRCH POLLEN ALLERGEN BET V 4
Descriptor:POLCALCIN BET V 4, CALCIUM ION
Authors:Neudecker, P., Nerkamp, J., Eisenmann, A., Lauber, T., Lehmann, K., Schweimer, K., Roesch, P.
Deposit date:2003-02-26
Release date:2004-02-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure, Dynamics, and Hydrodynamics of the Calcium-Bound Cross-Reactive Birch Pollen Allergen Bet V 4 Reveal a Canonical Monomeric Two EF-Hand Assembly with a Regulatory Function
J.Mol.Biol., 336, 2004
6B1G
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SOLUTION STRUCTURE OF TDP-43 N-TERMINAL DOMAIN DIMER.
Descriptor:TAR DNA-binding protein 43, S48E Mutant, Y4R Mutant
Authors:Naik, M.T., Wang, A., Conicella, A., Fawzi, N.L.
Deposit date:2017-09-18
Release date:2018-02-28
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
EMBO J., 37, 2018
2M03
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SOLUTION STRUCTURE OF BCL-XL DETERMINED WITH SELECTIVE ISOTOPE LABELLING OF I,L,V SIDECHAINS
Descriptor:Bcl-2-like protein 1
Authors:Viacava Follis, A., Royappa, G., Kriwacki, R.W.
Deposit date:2012-10-19
Release date:2013-01-30
Last modified:2013-03-06
Method:SOLUTION NMR
Cite:PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat.Chem.Biol., 9, 2013
2M04
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SOLUTION STRUCTURE OF BCL-XL IN COMPLEX WITH PUMA BH3 PEPTIDE
Descriptor:Bcl-2-like protein 1, Bcl-2-binding component 3
Authors:Viacava Follis, A., Royappa, G., Kriwacki, R.W.
Deposit date:2012-10-19
Release date:2013-01-30
Last modified:2013-03-06
Method:SOLUTION NMR
Cite:PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat.Chem.Biol., 9, 2013
2EKE
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STRUCTURE OF A SUMO-BINDING-MOTIF MIMIC BOUND TO SMT3P-UBC9P: CONSERVATION OF A NONCOVALENT UBIQUITIN-LIKE PROTEIN-E2 COMPLEX AS A PLATFORM FOR SELECTIVE INTERACTIONS WITHIN A SUMO PATHWAY
Descriptor:SUMO-conjugating enzyme UBC9, Ubiquitin-like protein SMT3
Authors:Duda, D.M., Schulman, B.A.
Deposit date:2007-03-23
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway
J.Mol.Biol., 369, 2007
2LK4
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STRUCTURAL AND MECHANISTIC INSIGHTS INTO THE INTERACTION BETWEEN PAT PYK2 AND PAXILLIN LD MOTIF
Descriptor:Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M., Miller, D., Guibao, C., Zheng, J.
Deposit date:2011-10-04
Release date:2012-10-10
Last modified:2014-12-31
Method:SOLUTION NMR
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
2M5B
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THE NMR STRUCTURE OF THE BID-BAK COMPLEX
Descriptor:Bcl-2 homologous antagonist/killer, human_BID_BH3_SAHB
Authors:Moldoveanu, T., Grace, C.R., Kriwacki, R.W., Green, D.R.
Deposit date:2013-02-19
Release date:2013-04-17
Last modified:2013-05-22
Method:SOLUTION NMR
Cite:BID-induced structural changes in BAK promote apoptosis.
Nat.Struct.Mol.Biol., 20, 2013
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