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Crystal Structure of TrkA kinase with ligand
Descriptor:	1-[(3S,4R)-4-[3,4-bis(fluoranyl)phenyl]-1-(2-methoxyethyl)pyrrolidin-3-yl]-3-(5-ethoxy-4-methyl-2-phenyl-pyrazol-3-yl)urea, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, High affinity nerve growth factor receptor, ...
Authors:	Noritaka, F.
Deposit date:	2016-10-26
Release date:	2017-02-22
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	The juxtamembrane region of TrkA kinase is critical for inhibitor selectivity Bioorg. Med. Chem. Lett., 27, 2017

Crystal structure of TrkA kinase with ligand
Descriptor:	4-[[4-azanyl-3-(4-cyclohexylpiperazin-1-yl)-9,10-bis(oxidanylidene)anthracen-1-yl]amino]benzoic acid, High affinity nerve growth factor receptor
Authors:	Noritaka, F.
Deposit date:	2018-11-08
Release date:	2020-01-22
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2.54 Å)
Cite:	An isoform-selective inhibitor of tropomyosin receptor kinase A behaves as molecular glue. Bioorg.Med.Chem.Lett., 30, 2020