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hRXRalpha & mLXRalpha with an indole Pharmacophore, SB786875
Descriptor:	Nr1h3 protein, RETINOIC ACID, Retinoic acid receptor RXR-alpha, ...
Authors:	Washburn, D.G, Hoang, T.H, Campobasso, N, Smallwood, A, Parks, D.J, Webb, C.L, Frank, K, Nord, M, Duraiswami, C, Evans, C, Jaye, M, Thompson, S.K.
Deposit date:	2008-11-21
Release date:	2009-02-10
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.063 Å)
Cite:	Synthesis and SAR of potent LXR agonists containing an indole pharmacophore. Bioorg.Med.Chem.Lett., 19, 2009

Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2
Descriptor:	Serine/threonine-protein kinase Sgk1, [4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid
Authors:	Zhao, B, Hammond, M.
Deposit date:	2009-05-07
Release date:	2009-06-30
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009

Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 1
Descriptor:	4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, Serine/threonine-protein kinase Sgk1
Authors:	Zhao, B, Hammond, M.
Deposit date:	2009-05-07
Release date:	2009-06-30
Last modified:	2021-10-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009