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4MYB
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BU of 4myb by Molmil
Crystal Structure of Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)
Descriptor: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Authors:Noble, S.M, Tsang, A.K, Couch, R.D.
Deposit date:2013-09-27
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)
To be Published
6O5H
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BU of 6o5h by Molmil
The effect of modifier structure on the activation of leukotriene A4 hydrolase aminopeptidase activity.
Descriptor: 4-{4-[(4-methoxyphenyl)methyl]phenyl}-1,3-thiazol-2-amine, Leukotriene A-4 hydrolase, ZINC ION
Authors:Noble, S.M, Lee, K.H, Paige, M.
Deposit date:2019-03-03
Release date:2019-12-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Effect of Modifier Structure on the Activation of Leukotriene A4Hydrolase Aminopeptidase Activity.
J.Med.Chem., 62, 2019
7S04
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BU of 7s04 by Molmil
1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Acinetobacter baumannii in complex with FR900098, NADPH, and a magnesium ion
Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[ethanoyl(hydroxy)amino]propylphosphonic acid, MAGNESIUM ION, ...
Authors:Noble, S.M, Ball, H.S, Couch, R.D.
Deposit date:2021-08-28
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Characterization and Inhibition of 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase: A Promising Drug Target in Acinetobacter baumannii and Klebsiella pneumoniae .
Acs Infect Dis., 7, 2021
7LLQ
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BU of 7llq by Molmil
Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity
Descriptor: 1-benzyl-4-methoxybenzene, 1-{4-oxo-4-[(2S)-pyrrolidin-2-yl]butanoyl}-L-proline, Leukotriene A-4 hydrolase, ...
Authors:Lee, K.H, Lee, S.H, Shim, Y.M, Paige, M, Noble, S.M.
Deposit date:2021-02-04
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation.
Sci Rep, 12, 2022
7KZE
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BU of 7kze by Molmil
Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity
Descriptor: 1-benzyl-4-methoxybenzene, Leukotriene A-4 hydrolase, TRIETHYLENE GLYCOL, ...
Authors:Lee, K.H, Shim, Y, Paige, M, Noble, S.M.
Deposit date:2020-12-10
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation.
Sci Rep, 12, 2022
1M13
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BU of 1m13 by Molmil
Crystal Structure of the Human Pregane X Receptor Ligand Binding Domain in Complex with Hyperforin, a Constituent of St. John's Wort
Descriptor: 4-HYDROXY-5-ISOBUTYRYL-6-METHYL-1,3,7-TRIS-(3-METHYL-BUT-2-ENYL)-6-(4-METHYL-PENT-3-ENYL)-BICYCLO[3.3.1]NON-3-ENE-2,9-DIONE, Orphan Nuclear Receptor PXR
Authors:Watkins, R.E, Maglich, J.M, Moore, L.B, Wisely, G.B, Noble, S.M, Davis-Searles, P.R, Lambert, M.H, Kliewer, S.A, Redinbo, M.R.
Deposit date:2002-06-17
Release date:2003-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:2.1 A Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin
Biochemistry, 42, 2003

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