Author results

1UMG
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CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATASE
Descriptor:385aa long conserved hypothetical protein, MAGNESIUM ION, 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), ...
Authors:Nishimasu, H., Fushinobu, S., Shoun, H., Wakagi, T.
Deposit date:2003-09-30
Release date:2004-07-13
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The first crystal structure of the novel class of fructose-1,6-bisphosphatase present in thermophilic archaea.
Structure, 12, 2004
2E2N
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CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN THE APO FORM
Descriptor:HEXOKINASE, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Nishimasu, H., Fushinobu, S., Shoun, H., Wakagi, T.
Deposit date:2006-11-15
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii.
J.Biol.Chem., 282, 2007
2E2O
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CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN COMPLEX WITH GLUCOSE
Descriptor:HEXOKINASE, BETA-D-GLUCOSE
Authors:Nishimasu, H., Fushinobu, S., Shoun, H., Wakagi, T.
Deposit date:2006-11-15
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii.
J.Biol.Chem., 282, 2007
2E2P
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CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN COMPLEX WITH ADP
Descriptor:HEXOKINASE, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Nishimasu, H., Fushinobu, S., Shoun, H., Wakagi, T.
Deposit date:2006-11-15
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii.
J.Biol.Chem., 282, 2007
2E2Q
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CRYSTAL STRUCTURE OF SULFOLOBUS TOKODAII HEXOKINASE IN COMPLEX WITH XYLOSE, MG2+, AND ADP
Descriptor:HEXOKINASE, BETA-D-XYLOPYRANOSE, MAGNESIUM ION, ...
Authors:Nishimasu, H., Fushinobu, S., Shoun, H., Wakagi, T.
Deposit date:2006-11-15
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii.
J.Biol.Chem., 282, 2007
3G5Q
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRMFO
Descriptor:Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO, FLAVIN-ADENINE DINUCLEOTIDE, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Nishimasu, H., Ishitani, R., Hori, H., Nureki, O.
Deposit date:2009-02-05
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Proc.Natl.Acad.Sci.USA, 106, 2009
3G5R
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRMFO IN COMPLEX WITH TETRAHYDROFOLATE
Descriptor:Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO, FLAVIN-ADENINE DINUCLEOTIDE, (6S)-5,6,7,8-TETRAHYDROFOLATE, ...
Authors:Nishimasu, H., Ishitani, R., Hori, H., Nureki, O.
Deposit date:2009-02-05
Release date:2009-05-19
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Proc.Natl.Acad.Sci.USA, 106, 2009
3G5S
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS TRMFO IN COMPLEX WITH GLUTATHIONE
Descriptor:Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, ...
Authors:Nishimasu, H., Ishitani, R., Hori, H., Nureki, O.
Deposit date:2009-02-05
Release date:2009-05-19
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Proc.Natl.Acad.Sci.USA, 106, 2009
4GEL
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CRYSTAL STRUCTURE OF ZUCCHINI
Descriptor:Mitochondrial cardiolipin hydrolase, ZINC ION, PHOSPHATE ION, ...
Authors:Nishimasu, H., Fukuhara, S., Ishitani, R., Nureki, O.
Deposit date:2012-08-02
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.756 Å)
Cite:Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GEM
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CRYSTAL STRUCTURE OF ZUCCHINI (K171A)
Descriptor:Mitochondrial cardiolipin hydrolase, ZINC ION, 1,2-ETHANEDIOL
Authors:Nishimasu, H., Fukuhara, S., Ishitani, R., Nureki, O.
Deposit date:2012-08-02
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GEN
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CRYSTAL STRUCTURE OF ZUCCHINI (MONOMER)
Descriptor:Mitochondrial cardiolipin hydrolase, CHLORIDE ION
Authors:Nishimasu, H., Fukuhara, S., Ishitani, R., Nureki, O.
Deposit date:2012-08-02
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
6AI6
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CRYSTAL STRUCTURE OF SPCAS9-NG
Descriptor:CRISPR-associated endonuclease Cas9/Csn1, RNA (81-MER), DNA (28-MER), ...
Authors:Nishimasu, H., Hirano, S., Ishitani, R., Nureki, O.
Deposit date:2018-08-21
Release date:2018-10-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Engineered CRISPR-Cas9 nuclease with expanded targeting space
Science, 361, 2018
3NKM
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKN
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 14:0-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKO
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 16:0-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKP
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:1-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKQ
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:3-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKR
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 22:6-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.704 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
4OO8
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES CAS9 IN COMPLEX WITH GUIDE RNA AND TARGET DNA
Descriptor:CRISPR-associated endonuclease Cas9/Csn1, RNA (97-MER), DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3')
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2014-01-31
Release date:2014-02-26
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Cas9 in complex with guide RNA and target DNA
Cell(Cambridge,Mass.), 156, 2014
5AXW
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CAS9 IN COMPLEX WITH SGRNA AND TARGET DNA (TTGGGT PAM)
Descriptor:CRISPR-associated endonuclease Cas9, RNA (73-MER), DNA (28-MER), ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2015-08-01
Release date:2015-09-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Staphylococcus aureus Cas9
Cell(Cambridge,Mass.), 162, 2015
5CZZ
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS CAS9 IN COMPLEX WITH SGRNA AND TARGET DNA (TTGAAT PAM)
Descriptor:CRISPR-associated endonuclease Cas9, RNA (73-MER), DNA (28-MER), ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2015-08-01
Release date:2015-09-02
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Staphylococcus aureus Cas9
Cell(Cambridge,Mass.), 162, 2015
5XH6
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CRYSTAL STRUCTURE OF THE ACIDAMINOCOCCUS SP. BV3L6 CPF1 RVR VARIANT IN COMPLEX WITH CRRNA AND TARGET DNA (TATA PAM)
Descriptor:CRISPR-associated endonuclease Cpf1, crRNA, Target DNA strand, ...
Authors:Nishimasu, H., Yamano, T., Ishitani, R., Nureki, O.
Deposit date:2017-04-19
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol. Cell, 67, 2017
5XH7
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CRYSTAL STRUCTURE OF THE ACIDAMINOCOCCUS SP. BV3L6 CPF1 RR VARIANT IN COMPLEX WITH CRRNA AND TARGET DNA (TCCA PAM)
Descriptor:CRISPR-associated endonuclease Cpf1, crRNA, Target DNA strand, ...
Authors:Nishimasu, H., Yamano, T., Ishitani, R., Nureki, O.
Deposit date:2017-04-19
Release date:2017-06-14
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol. Cell, 67, 2017
3WAV
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH COMPOUND 10
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
3WAW
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 2BOA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
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