Author results

2OGQ
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MOLECULAR AND STRUCTURAL BASIS OF PLK1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION
Descriptor:Serine/threonine-protein kinase PLK1
Authors:Garcia-Alvarez, B., de Carcer, G., Ibanez, S., Bragado-Nilsson, E., Montoya, G.
Deposit date:2007-01-08
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OJX
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MOLECULAR AND STRUCTURAL BASIS OF POLO-LIKE KINASE 1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION
Descriptor:Serine/threonine-protein kinase PLK1, Synthetic peptide
Authors:Garcia-Alvarez, B., de Carcer, G., Ibanez, S., Bragado-Nilsson, E., Montoya, G.
Deposit date:2007-01-15
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2WGT
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STRUCTURE OF HUMAN ADENOVIRUS SEROTYPE 37 FIBRE HEAD IN COMPLEX WITH A SIALIC ACID DERIVATIVE, O-METHYL 5-N-PROPAONYL-3,5-DIDEOXY-D- GLYCERO-A-D-GALACTO-2-NONULOPYRANOSYLONIC ACID
Descriptor:FIBER PROTEIN, 3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC ACID, ZINC ION
Authors:Johansson, S., Nilsson, E., Qian, W., Guilligay, D., Crepin, T., Cusack, S., Arnberg, N., Elofsson, M.
Deposit date:2009-04-27
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis.
J.Med.Chem., 52, 2009
2WGU
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STRUCTURE OF HUMAN ADENOVIRUS SEROTYPE 37 FIBRE HEAD IN COMPLEX WITH A SIALIC ACID DERIVATIVE, O-METHYL 5-N- METHOXYCARBONYL -3,5-DIDEOXY- D-GLYCERO-A-D-GALACTO-2-NONULOPYRANOSYLONIC ACID
Descriptor:FIBER PROTEIN, 3,5-dideoxy-5-[(methoxycarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ZINC ION
Authors:Johansson, S., Nilsson, E., Qian, W., Guilligay, D., Crepin, T., Cusack, S., Arnberg, N., Elofsson, M.
Deposit date:2009-04-27
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis.
J.Med.Chem., 52, 2009
2XSM
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CRYSTAL STRUCTURE OF THE MAMMALIAN CYTOSOLIC CHAPERONIN CCT IN COMPLEX WITH TUBULIN
Descriptor:CCT
Authors:Munoz, I.G., Yebenes, H., Zhou, M., Mesa, P., Serna, M., Bragado-Nilsson, E., Beloso, A., Robinson, C.V., Valpuesta, J.M., Montoya, G.
Deposit date:2010-10-29
Release date:2010-12-15
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structure of the Open Conformation of the Mammalian Chaperonin Cct in Complex with Tubulin.
Nat.Struct.Mol.Biol., 18, 2011
3BZI
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MOLECULAR AND STRUCTURAL BASIS OF POLO-LIKE KINASE 1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION
Descriptor:Serine/threonine-protein kinase PLK1, 9 mer peptide from M-phase inducer phosphatase 3, FORMIC ACID
Authors:Garcia-Alvarez, B., de Carcer, G., Ibanez, S., Bragado-Nilsson, E., Montoya, G.
Deposit date:2008-01-18
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4QE6
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FXR WITH CDCA AND NCOA-2 PEPTIDE
Descriptor:Bile acid receptor, Nuclear receptor coactivator 2, CHENODEOXYCHOLIC ACID, ...
Authors:Kudlinzki, D., Merk, D., Linhard, V.L., Saxena, K., Sreeramulu, S., Nilsson, E., Dekker, N., Wissler, L., Bamberg, K., Schubert-Zsilavecz, M., Schwalbe, H.
Deposit date:2014-05-15
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.648 Å)
Cite:FXR with CDCA and NCoA-2 peptide
To be Published
4QE8
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FXR WITH DM175 AND NCOA-2 PEPTIDE
Descriptor:Bile acid receptor, Nuclear receptor coactivator 2, 4-({2-[(4-tert-butylbenzoyl)amino]benzoyl}amino)benzoic acid, ...
Authors:Kudlinzki, D., Merk, D., Linhard, V.L., Saxena, K., Sreeramulu, S., Nilsson, E., Dekker, N., Wissler, L., Bamberg, K., Schubert-Zsilavecz, M., Schwalbe, H.
Deposit date:2014-05-15
Release date:2015-08-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:FXR with DM175 and NCoA-2 peptide
To be Published
4UDA
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MR IN COMPLEX WITH DEXAMETHASONE
Descriptor:MINERALOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 1, GLYCEROL, ...
Authors:Edman, K., Hogner, A., Hussein, A., Bjursell, M., Aagaard, A., Backstrom, S., Bodin, C., Wissler, L., Jellesmark-Jensen, T., Cavallin, A., Karlsson, U., Nilsson, E., Lecina, D., Takahashi, R., Grebner, C., Lepisto, M., Guallar, V.
Deposit date:2014-12-09
Release date:2015-11-25
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints.
Structure, 23, 2015
4UDB
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MR IN COMPLEX WITH DESISOBUTYRYLCICLESONIDE
Descriptor:MINERALOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 1, DIMETHYL SULFOXIDE, ...
Authors:Edman, K., Hogner, A., Hussein, A., Aagaard, A., Backstrom, S., Bodin, C., Wissler, L., JellesmarkJensen, T., Cavallin, A., Nilsson, E., Lepisto, M., Guallar, V.
Deposit date:2014-12-09
Release date:2015-11-25
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints.
Structure, 23, 2015
4UDC
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GR IN COMPLEX WITH DEXAMETHASONE
Descriptor:GLUCOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 2, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ...
Authors:Edman, K., Hogner, A., Hussein, A., Bjursell, M., Aagaard, A., Backstrom, S., Bodin, C., Wissler, L., Jellesmark-Jensen, T., Cavallin, A., Karlsson, U., Nilsson, E., Lecina, D., Takahashi, R., Grebner, C., Lepisto, M., Guallar, V.
Deposit date:2014-12-09
Release date:2015-11-25
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints.
Structure, 23, 2015
4UDD
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GR IN COMPLEX WITH DESISOBUTYRYLCICLESONIDE
Descriptor:GLUCOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 2, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ...
Authors:Edman, K., Hogner, A., Hussein, A., Bjursell, M., Aagaard, A., Backstrom, S., Bodin, C., Wissler, L., Jellesmark-Jensen, T., Cavallin, A., Karlsson, U., Nilsson, E., Lecina, D., Takahashi, R., Grebner, C., Lepisto, M., Guallar, V.
Deposit date:2014-12-09
Release date:2015-11-25
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints.
Structure, 23, 2015
5FX5
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NOVEL INHIBITORS OF HUMAN RHINOVIRUS 3C PROTEASE
Descriptor:RHINOVIRUS 3C PROTEASE, GLYCEROL, TETRAETHYLENE GLYCOL, ...
Authors:Kawatkar, S., Ek, M., Hoesch, V., Gagnon, M., Nilsson, E., Lister, T., Olsson, L., Patel, J., Yu, Q.
Deposit date:2016-02-24
Release date:2016-06-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
5FX6
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NOVEL INHIBITORS OF HUMAN RHINOVIRUS 3C PROTEASE
Descriptor:RHINOVIRUS 3C PROTEASE, ethyl (4R)-4-[[(2S,4S)-1-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]butanoyl]-4-phenyl-pyrrolidin-2-yl]carbonylamino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate
Authors:Kawatkar, S., Ek, M., Hoesch, V., Gagnon, M., Nilsson, E., Lister, T., Olsson, L., Patel, J., Yu, Q.
Deposit date:2016-02-24
Release date:2016-06-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
2JA4
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CRYSTAL STRUCTURE OF CD5 DOMAIN III REVEALS THE FOLD OF A GROUP B SCAVENGER CYSTEINE-RICH RECEPTOR
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD5
Authors:Rodamilans, B., Munoz, I.G., Sarrias, M.R., Lozano, F., Blanco, F.J., Montoya, G.
Deposit date:2006-11-21
Release date:2007-03-06
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of the Third Extracellular Domain of Cd5 Reveals the Fold of a Group B Scavenger Cysteine-Rich Receptor Domain.
J.Biol.Chem., 282, 2007
2OTT
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CRYSTAL STRUCTURE OF CD5_DIII
Descriptor:T-cell surface glycoprotein CD5
Authors:Rodamilans, B.
Deposit date:2007-02-09
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain.
J.Biol.Chem., 282, 2007
2VCQ
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COMPLEX STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE AT 1.95A.
Descriptor:GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, GLUTATHIONE, 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole
Authors:Hohwy, M., Spadola, L., Lundquist, B., von Wachenfeldt, K., Persdotter, S., Hawtin, P., Dahmen, J., Groth-Clausen, I., Folmer, R.H.A., Edman, K.
Deposit date:2007-09-26
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
2VCW
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COMPLEX STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE AT 1.95A.
Descriptor:GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, GLUTATHIONE, 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Authors:Hohwy, M., Spadola, L., Lundquist, B., von Wachenfeldt, K., Persdotter, S., Hawtin, P., Dahmen, J., Groth-Clausen, I., Folmer, R.H.A., Edman, K.
Deposit date:2007-09-27
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
2VCX
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COMPLEX STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE AT 2.1A.
Descriptor:GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, MAGNESIUM ION, GLUTATHIONE, ...
Authors:Hohwy, M., Spadola, L., Lundquist, B., von Wachenfeldt, K., Persdotter, S., Hawtin, P., Dahmen, J., Groth-Clausen, I., Folmer, R.H.A., Edman, K.
Deposit date:2007-09-27
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
2VCZ
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COMPLEX STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE AT 1.95A.
Descriptor:GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, GLUTATHIONE, 3-(4-nitrophenyl)-1H-pyrazole
Authors:Hohwy, M., Spadola, L., Lundquist, B., von Wachenfeldt, K., Persdotter, S., Hawtin, P., Dahmen, J., Groth-Clausen, I., Folmer, R.H.A., Edman, K.
Deposit date:2007-09-28
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
2VD0
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COMPLEX STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE AT 2.2A.
Descriptor:GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, GLUTATHIONE, 2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid, ...
Authors:Hohwy, M., Spadola, L., Lundquist, B., von Wachenfeldt, K., Persdotter, S., Hawtin, P., Dahmen, J., Groth-Clausen, I., Folmer, R.H.A., Edman, K.
Deposit date:2007-09-28
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
2VD1
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COMPLEX STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE AT 2.25A.
Descriptor:GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, GLUTATHIONE, 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid, ...
Authors:Hohwy, M., Spadola, L., Lundquist, B., von Wachenfeldt, K., Persdotter, S., Hawtin, P., Dahmen, J., Groth-Clausen, I., Folmer, R.H.A., Edman, K.
Deposit date:2007-09-28
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
4XL8
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CRYSTAL STRUCTURE OF HUMAN ADENOVIRUS 52 SHORT FIBER KNOB IN COMPLEX WITH 2-O-METHYL-5-N-ACETYLNEURAMINIC ACID
Descriptor:Fiber-1, 2-O-METHYL-5-N-ACETYL-ALPHA-D- NEURAMINIC ACID, GLYCEROL, ...
Authors:Stehle, T., Liaci, A.M.
Deposit date:2015-01-13
Release date:2015-01-21
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells.
Plos Pathog., 11, 2015
4B2T
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THE CRYSTAL STRUCTURES OF THE EUKARYOTIC CHAPERONIN CCT REVEAL ITS FUNCTIONAL PARTITIONING
Descriptor:T-COMPLEX PROTEIN 1 SUBUNIT ALPHA, T-COMPLEX PROTEIN 1 SUBUNIT BETA, T-COMPLEX PROTEIN 1 SUBUNIT DELTA, ...
Authors:Kalisman, N., Schroeder, G.F., Levitt, M.
Deposit date:2012-07-17
Release date:2013-03-20
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning
Structure, 21, 2013