Author results

6GC4
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 3
Descriptor:50S ribosomal protein L25, 23S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-07-04
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC6
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 2
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-07-04
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GBZ
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 5
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC0
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 4
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC7
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 1
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC8
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE - 50S REC*
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
4CXG
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4CXH
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4UJE
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:TRNA-LYS, TRNA-PHE, Messenger RNA, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-05
Release date:2014-07-16
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4V6T
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STRUCTURE OF THE BACTERIAL RIBOSOME COMPLEXED BY TMRNA-SMPB AND EF-G DURING TRANSLOCATION AND MLD-LOADING
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Ramrath, D.J.F., Yamamoto, H., Rother, K., Wittek, D., Pech, M., Mielke, T., Loerke, J., Scheerer, P., Ivanov, P., Teraoka, Y., Shpanchenko, O., Nierhaus, K.H., Spahn, C.M.T.
Deposit date:2012-01-27
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
Nature, 485, 2012
3J0L
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 9.8A CRYO-EM MAP: CLASSIC PRE STATE 1
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S5, Ribosomal protein S14, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-04
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0O
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 9A CRYO-EM MAP: CLASSIC PRE STATE 2
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S5, Ribosomal protein S14, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-05
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0P
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 10.6A CRYO-EM MAP: ROTATED PRE STATE 1
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S15, Ribosomal protein S23, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-06
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0Q
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 10.6A CRYO-EM MAP: ROTATED PRE STATE 2
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S15, Ribosomal protein S23, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-11
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3DEG
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COMPLEX OF ELONGATING ESCHERICHIA COLI 70S RIBOSOME AND EF4(LEPA)-GMPPNP
Descriptor:A/L-tRNA, P-tRNA, 30S RNA helix 8, ...
Authors:Connell, S.R., Topf, M., Qin, Y., Wilson, D.N., Mielke, T., Fucini, P., Nierhaus, K.H., Spahn, C.M.T.
Deposit date:2008-06-10
Release date:2008-08-19
Last modified:2014-04-16
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
2HHH
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CRYSTAL STRUCTURE OF KASUGAMYCIN BOUND TO THE 30S RIBOSOMAL SUBUNIT
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Schluenzen, F.
Deposit date:2006-06-28
Release date:2006-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006
1ZC8
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COORDINATES OF TMRNA, SMPB, EF-TU AND H44 FITTED INTO CRYO-EM MAP OF THE 70S RIBOSOME AND TMRNA COMPLEX
Descriptor:TLD 16S ribosomal RNA, H2 16S rRNA, H2b d mRNA, ...
Authors:Valle, M., Gillet, R., Kaur, S., Henne, A., Ramakrishnan, V., Frank, J.
Deposit date:2005-04-11
Release date:2005-04-19
Last modified:2013-12-11
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Visualizing tmRNA Entry into a Stalled Ribosome
Science, 300, 2003
1OMS
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STRUCTURE DETERMINATION BY MAD: E.COLI TRIGGER FACTOR BINDING AT THE RIBOSOMAL EXIT TUNNEL.
Descriptor:Trigger Factor, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Kristensen, O., Gajhede, M.
Deposit date:2003-02-26
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Chaperone binding at the ribosomal exit tunnel.
Structure, 11, 2003
1P9Y
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RIBOSOME BINDING OF E. COLI TRIGGER FACTOR MUTANT F44L.
Descriptor:Trigger factor, ACETIC ACID
Authors:Kristensen, O., Gajhede, M.
Deposit date:2003-05-13
Release date:2003-12-16
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Chaperone binding at the ribosomal exit tunnel.
Structure, 11, 2003
1LS2
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FITTING OF EF-TU AND TRNA IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:Phenylalanine transfer RNA, Elongation Factor Tu
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1LU3
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SEPARATE FITTING OF THE ANTICODON LOOP REGION OF TRNA (NUCLEOTIDE 26-42) IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:PHENYLALANINE TRANSFER RNA
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-21
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1JQM
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FITTING OF L11 PROTEIN AND ELONGATION FACTOR G (EF-G) IN THE CRYO-EM MAP OF E. COLI 70S RIBOSOME BOUND WITH EF-G, GDP AND FUSIDIC ACID
Descriptor:50S Ribosomal protein L11, Elongation Factor G
Authors:Agrawal, R.K., Linde, J., Segupta, J., Nierhaus, K.H., Frank, J.
Deposit date:2001-08-07
Release date:2001-09-07
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation.
J.Mol.Biol., 311, 2001
1JQS
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FITTING OF L11 PROTEIN AND ELONGATION FACTOR G (DOMAIN G' AND V) IN THE CRYO-EM MAP OF E. COLI 70S RIBOSOME BOUND WITH EF-G AND GMPPCP, A NONHYDROLYSABLE GTP ANALOG
Descriptor:50S Ribosomal protein L11, Elongation Factor G
Authors:Agrawal, R.K., Linde, J., Segupta, J., Nierhaus, K.H., Frank, J.
Deposit date:2001-08-07
Release date:2001-09-07
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation.
J.Mol.Biol., 311, 2001
1JQT
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FITTING OF L11 PROTEIN IN THE LOW RESOLUTION CRYO-EM MAP OF E.COLI 70S RIBOSOME
Descriptor:50S Ribosomal protein L11
Authors:Agrawal, R.K., Linde, J., Segupta, J., Nierhaus, K.H., Frank, J.
Deposit date:2001-08-07
Release date:2001-09-07
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation.
J.Mol.Biol., 311, 2001
1FCW
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TRNA POSITIONS DURING THE ELONGATION CYCLE
Descriptor:TRNAPHE
Authors:Agrawal, R.K., Spahn, C.M.T., Penczek, P., Grassucci, R.A., Nierhaus, K.H., Frank, J.
Deposit date:2000-07-19
Release date:2000-08-11
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle.
J.Cell Biol., 150, 2000